Protein

MCA_03592_1

Length
669 amino acids


Gene name: MET30A

Description: F-box protein MET30; F-box protein containing five copies of the WD40 motif; controls cell cycle function, sulfur metabolism, and methionine biosynthesis as part of the ubiquitin ligase complex

Browser: contigC:447779-449789-

RNA-seq: read pairs 1685, FPKM 31.1, percentile rank 53.7% (100% = highest expression)

Protein function

Annotation:MET30AF-box protein MET30; F-box protein containing five copies of the WD40 motif; controls cell cycle function, sulfur metabolism, and methionine biosynthesis as part of the ubiquitin ligase complex
KEGG:K10259MET30 F-box and WD-40 domain protein MET30
EGGNOG:0QDQXSCONBComponent of the SCF(sconB) E3 ubiquitin ligase complex involved in the regulation of sulfur metabolite repression, probably by mediating the inactivation or degradation of the metR transcription factor
SGD closest match:S000001308MET30F-box protein MET30
CGD closest match:CAL0000190294orf19.3301Ubiquitin-binding SDF ubiquitin ligase complex subunit

Protein alignments

%idAln lengthE-value
MIA_03731_169.38%6630.0MIA_03731_1
A0A0J9XDY5_GEOCN54.03%6700.0Similar to Saccharomyces cerevisiae YIL046W MET30 F-box protein containing five copies of the WD40 motif OS=Geotrichum candidum GN=BN980_GECA11s02144g PE=4 SV=1
UniRef50_A0A0J9XDY554.03%6700.0Similar to Saccharomyces cerevisiae YIL046W MET30 F-box protein containing five copies of the WD40 motif n=2 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XDY5_GEOCN
A0A167CRX6_9ASCO52.12%7060.0Met30p OS=Sugiyamaella lignohabitans GN=MET30 PE=4 SV=1
W0TYP9_YARLI51.31%6470.0YALI0B09977p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B09977g PE=4 SV=1
Q5A933_CANAL44.63%6520.0Ubiquitin-binding SDF ubiquitin ligase complex subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.3301 PE=4 SV=1
A0A060TG27_BLAAD56.70%4550.0ARAD1D27610p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D27610g PE=4 SV=1
MET30_YEAST42.11%6468e-169F-box protein MET30 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MET30 PE=1 SV=1
A0A1E3PCN4_9ASCO49.20%4371e-149WD40 repeat-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_84543 PE=4 SV=1
A0A1E4TDM8_9ASCO38.71%6202e-148Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_28039 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0348

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
  3. Repeat
  4. Repeat
1 100 200 300 400 500 600 669

Detailed signature matches

    1. SSF81383 (F-box domain)
    2. PS50181 (FBOX)
    3. SM00256 (fbox_2)
    4. PF12937 (F-box-like)
    1. PF12894 (ANAPC4_WD40)
    1. SSF50978 (WD40 repe...)
    2. PS50294 (WD_REPEATS...)
    1. PF00400 (WD40)
    2. PS50082 (WD_REPEATS_2)
    3. SM00320 (WD40_4)
    1. PR00320 (GPROTEINBRPT)
    1. PS00678 (WD_REPEATS_1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd00200 (WD40)
  2. mobidb-lite (disord...)

Residue annotation

  1. structural tetrad ...

Protein sequence

>MCA_03592_1
MDSSPLSSSTASKDSSVPQQEQSSKASNTSLPVIFEHKPALSKSISEKGMQNYCYRHHPNVLCNRQADATQMKEIQSDLD
KLDDNARTAISHVWSIFSAAPSKQRSLILKGLLAQCCFPQLSQVSSLLDNLIRIDFISALPPEISFKILSYLDSTSLCRA
AQVNKKWKLLADDDVVWHRMCEQHIDKKCTKCGWGLPLLEKKRLRDSRKDIDARVQELNEKTKIENETFNSNNKRPLEAT
ESTSITESNAPKKRKTRPWKEVYRERYNIESNWRNGRYKTLKFQHKSPVLCLQFDDQYLMVGTYDGKVSIWDVETGKMVR
QLEGHSKAVSALKFDNLKLITASRDQTVRVWNYRNGDCVCTFRGHEDAVLCIDCDQRLIASGSADRNIKVWNFATKTCFT
LRGHTDWVQSVRVHSASGTLYSGSEDTTIRMWDLVTKQCVRVFSAPGSQGSHVAQIQSVIPLYIDHLQGDENGCSMPNHR
SDSNAGAFPPPNFGRSQSENPTSSQENSEALSPISTSGGSPAPSEREVETVQRQNSYAVDKFPQSNHGGRADPLSTDERV
KRMNARPTHILSASLDSTIKMWDVKTGQCVRTLFGHIEGIWGIAADNFRVVSASHDKLVKVWDLQSGRNWHTFNDHTSHV
SCVGLSDTRLASGSDDGEVQMLCFDDFKK

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0005515 protein binding

Cellular Component

None predicted.