MCA_03549_1

Protein

Length

550 amino acids

RNA-seq: read pairs 12, FPKM 0.3, percentile rank 5.4% (100% = highest expression)

Protein function

EGGNOG:	0QE3B	FG03772.1	MFS transporter of unkown specificity
SGD closest match:	S000005905	YOR378W	Drug resistance protein YOR378W
CGD closest match:	CAL0000192014	orf19.2350	Uncharacterized protein

Protein alignments

	%id	Aln length	E-value
MIA_04894_1	60.50%	476	0.0	MIA_04894_1
Q59WF2_CANAL	46.39%	526	5e-155	Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.2350 PE=4 SV=1
UniRef50_Q59WF2	46.39%	526	1e-151	Uncharacterized protein n=21 Tax=Saccharomycetales TaxID=4892 RepID=Q59WF2_CANAL
YO378_YEAST	48.81%	463	3e-142	Drug resistance protein YOR378W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YOR378W PE=1 SV=1
A0A060T9P2_BLAAD	44.12%	485	8e-124	ARAD1D20108p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D20108g PE=4 SV=1
A0A161HK49_9ASCO	38.42%	531	6e-115	Amf1p OS=Sugiyamaella lignohabitans GN=AMF1 PE=4 SV=1
A0A1E3PEI3_9ASCO	29.79%	423	1e-48	Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_71964 PE=4 SV=1
Q6C2L1_YARLI	28.05%	467	1e-42	YALI0F06908p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F06908g PE=4 SV=1
A0A0J9XHK3_GEOCN	27.58%	475	2e-37	Similar to Saccharomyces cerevisiae YOR378W Putative paralog of ATR1, member of the DHA2 family of drug:H+ antiporters OS=Geotrichum candidum GN=BN980_GECA18s01737g PE=4 SV=1
A0A1E4TJU9_9ASCO	28.04%	428	6e-33	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_80956 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0030

Protein family membership

Major facilitator superfamily (IPR011701)

Domains and repeats

Domain
68 - 535
Major facilitator superfamily domain (IPR020846)

1 100 200 300 400 500 550

Detailed signature matches

IPR011701

Major facilitator superfamily
1. PF07690 (MFS_1)
  
  71 - 477
  
  Pfam
  PF07690 (MFS_1)
IPR020846

Major facilitator superfamily domain
1. PS50850 (MFS)
  
  68 - 525
  
  PROSITE profiles
  PS50850 (MFS)
2. SSF103473 (MFS gene...)
  
  317 - 535
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)
  
  69 - 262
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)
3. cd06174 (MFS)
  
  69 - 521
  
  CDD
  cd06174 (MFS)

no IPR

Unintegrated signatures

CYTOPLASMIC_D... (C...)

317 - 335

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

189 - 194

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

440 - 459

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

1 - 65

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

523 - 550

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

393 - 398

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

248 - 266

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

124 - 134

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)
Coil

26 - 46

COILS
Coil (Coil)
G3DSA:1.20.12...

62 - 265

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

334 - 547

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)
NON_CYTOPLASM... (N...)

216 - 226

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

418 - 422

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

355 - 373

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

483 - 501

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

86 - 104

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

287 - 297

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

156 - 166

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)
TMhelix

225 - 247

TMHMM
TMhelix (TMhelix)

68 - 90

TMHMM
TMhelix (TMhelix)

462 - 484

TMHMM
TMhelix (TMhelix)

267 - 286

TMHMM
TMhelix (TMhelix)

399 - 418

TMHMM
TMhelix (TMhelix)

195 - 215

TMHMM
TMhelix (TMhelix)

504 - 526

TMHMM
TMhelix (TMhelix)

296 - 315

TMHMM
TMhelix (TMhelix)

105 - 127

TMHMM
TMhelix (TMhelix)

370 - 392

TMHMM
TMhelix (TMhelix)

428 - 450

TMHMM
TMhelix (TMhelix)

336 - 355

TMHMM
TMhelix (TMhelix)

134 - 156

TMHMM
TMhelix (TMhelix)

166 - 188

TMHMM
TMhelix (TMhelix)
TRANSMEMBRANE (Tran...)

502 - 522

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

399 - 417

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

167 - 188

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

374 - 392

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

298 - 316

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

336 - 354

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

135 - 155

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

66 - 85

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

105 - 123

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

267 - 286

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

460 - 482

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

227 - 247

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

195 - 215

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

423 - 439

PHOBIUS
TRANSMEMBRANE (Transmembrane region)
mobidb-lite (disord...)

1 - 35

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

putative substrate...

83T

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

86T

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

87I

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

88V

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

90F

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

91K

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

109S

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

112F

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

113S

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

116V

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

120I

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

121L

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

123A

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

124G

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

173P

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

174A

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

177M

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

178P

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

181V

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

182G

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

185G

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

198M

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

199C

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

202A

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

203A

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

209F

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

287N

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

348F

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

349G

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

352V

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

353Y

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

356H

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

370M

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

374F

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

378A

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

381G

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

385G

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

436G

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

439M

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

440E

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

443F

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

447T

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

448V

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

451S

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

462A

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

463A

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

466V

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

467N

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

470V

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

471N

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

474I

putative substrate translocation pore
83T, 86T, 87I, 88V, 90F, 91K, 109S, 112F, 113S, 116V, 120I, 121L, 123A, 124G, 173P, 174A, 177M, 178P, 181V, 182G, 185G, 198M, 199C, 202A, 203A, 209F, 287N, 348F, 349G, 352V, 353Y, 356H, 370M, 374F, 378A, 381G, 385G, 436G, 439M, 440E, 443F, 447T, 448V, 451S, 462A, 463A, 466V, 467N, 470V, 471N, 474I
CDD
cd06174 (MFS)

Protein sequence

>MCA_03549_1
MEKNIDDTYDNDQKIKPFNESSIEIQEEKEEEKNGLEKTISKASSHIEGMLDPSIPYDQISLPREILFIFLLCLGQLFTQ
ASTAQTIVPFKYEAETFRTHNPGEISWFSAGFSLTVGTFILIAGRLGDMYGLKNMLLLGFAWYSVWSIVAGLSSYSHSHI
FFATARALQGIGPAFVMPNAVGIIGSYYPVGTRRIIAMCCFAAISPAGFVVGSVFSSMTAQLATWQWGFYCMGIACFVVG
VLSYFVIPENIGVQKVNGDGEEEKQTFDIWGAVTGVSGLFLFNFAWNQGPVVGWNVPYVYVLLIVGVLIIISFFVIERRV
KDPIVPQEILRGETGAILGCIAAGWSCFGIWVYYTHQFGIEIEGRTALDMSARFAPVAIFGCMVGVSVAVLLRYAPSSII
IFLSMVAFCGGTIIMGLRPVNEIYWAQMFVAQLVMGYGMEMSFPAGTVILSQKLPQNKQGVAASIVNTVVNYSISIGLGI
AGTVEYYSIKHGQSKLQSIRNAFYTGMALSAVGVLLGLYFIYNQVIAPKYLKNKNLQKENQEPEEEQKIA

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

None predicted.

Cellular Component

GO:0016021 integral component of membrane

Filter view on

Entry type

Status

Per-residue features