MCA_03536_1

Protein

Length

621 amino acids

RNA-seq: read pairs 33, FPKM 0.7, percentile rank 7.8% (100% = highest expression)

Protein function

EGGNOG:	0PFST	FG03636.1	MFS transporter (Seo1)
SGD closest match:	S000000062	SEO1	Probable transporter SEO1
CGD closest match:	CAL0000175721	CAALFM_CR06790CA	Uncharacterized protein

Protein alignments

	%id	Aln length	E-value
MIA_00276_1	73.32%	566	0.0	MIA_00276_1
UniRef50_F2QQK0	59.89%	556	0.0	Biotin symporter n=11 Tax=Saccharomycetales TaxID=4892 RepID=F2QQK0_KOMPC
A0A0J9XCA2_GEOCN	59.00%	561	0.0	Similar to Saccharomyces cerevisiae YAL067C SEO1 Putative permease OS=Geotrichum candidum GN=BN980_GECA09s00208g PE=4 SV=1
A0A1E3PMS6_9ASCO	58.98%	490	0.0	MFS general substrate transporter OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46126 PE=4 SV=1
A0A060SWU6_BLAAD	57.59%	507	0.0	ARAD1A08228p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A08228g PE=4 SV=1
Q6C1T2_YARLI	53.75%	506	0.0	YALI0F13607p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F13607g PE=4 SV=1
Q59MT5_CANAL	49.81%	516	3e-177	Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CAALFM_CR06790CA PE=4 SV=1
SEO1_YEAST	50.90%	501	8e-177	Probable transporter SEO1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SEO1 PE=1 SV=1
A0A161HL86_9ASCO	29.96%	514	2e-53	Putative permease SEO1 OS=Sugiyamaella lignohabitans GN=SEO1 PE=4 SV=1
A0A1E4TD78_9ASCO	24.83%	451	9e-23	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_142936 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2202

Protein family membership

Major facilitator superfamily (IPR011701)

Domains and repeats

Domain
106 - 549
Major facilitator superfamily domain (IPR020846)

1 100 200 300 400 500 621

Detailed signature matches

IPR011701

Major facilitator superfamily
1. PF07690 (MFS_1)
  
  132 - 500
  
  Pfam
  PF07690 (MFS_1)
IPR020846

Major facilitator superfamily domain
1. SSF103473 (MFS gene...)
  
  106 - 549
  
  SUPERFAMILY
  SSF103473 (MFS general substrate transporter)
2. cd06174 (MFS)
  
  128 - 538
  
  CDD
  cd06174 (MFS)

no IPR

Unintegrated signatures

CYTOPLASMIC_D... (C...)

1 - 118

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

476 - 486

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

416 - 426

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

187 - 192

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

543 - 621

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

310 - 361

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)

244 - 254

PHOBIUS
CYTOPLASMIC_DOMAIN (Cytoplasmic domain)
G3DSA:1.20.12...

349 - 554

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)

115 - 319

GENE3D
G3DSA:1.20.1250.20 (G3DSA:1.20.1250.20)
NON_CYTOPLASM... (N...)

138 - 168

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

448 - 452

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

387 - 397

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

510 - 520

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

276 - 286

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)

212 - 222

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)
TMhelix

164 - 186

TMHMM
TMhelix (TMhelix)

401 - 423

TMHMM
TMhelix (TMhelix)

191 - 208

TMHMM
TMhelix (TMhelix)

253 - 275

TMHMM
TMhelix (TMhelix)

453 - 475

TMHMM
TMhelix (TMhelix)

218 - 240

TMHMM
TMhelix (TMhelix)

520 - 542

TMHMM
TMhelix (TMhelix)

488 - 510

TMHMM
TMhelix (TMhelix)

290 - 309

TMHMM
TMhelix (TMhelix)

119 - 137

TMHMM
TMhelix (TMhelix)
TRANSMEMBRANE (Tran...)

487 - 509

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

427 - 447

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

223 - 243

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

255 - 275

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

169 - 186

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

193 - 211

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

398 - 415

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

521 - 542

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

362 - 386

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

287 - 309

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

119 - 137

PHOBIUS
TRANSMEMBRANE (Transmembrane region)

453 - 475

PHOBIUS
TRANSMEMBRANE (Transmembrane region)
mobidb-lite (disord...)

567 - 621

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

putative substrate...

142Q

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

145L

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

146N

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

147N

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

149Y

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

150V

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

168Q

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

171Y

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

172T

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

175S

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

179Q

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

180I

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

182F

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

183M

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

229E

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

230S

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

233Y

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

234P

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

237H

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

238Y

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

241G

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

253G

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

254G

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

257Y

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

258F

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

264I

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

373W

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

376N

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

377N

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

380S

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

381G

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

384L

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

398V

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

402S

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

406P

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

409G

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

413I

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

461Q

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

464G

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

465W

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

468S

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

472Y

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

473S

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

476A

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

489T

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

490V

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

493M

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

494N

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

497G

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

498Q

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

501T

putative substrate translocation pore
142Q, 145L, 146N, 147N, 149Y, 150V, 168Q, 171Y, 172T, 175S, 179Q, 180I, 182F, 183M, 229E, 230S, 233Y, 234P, 237H, 238Y, 241G, 253G, 254G, 257Y, 258F, 264I, 373W, 376N, 377N, 380S, 381G, 384L, 398V, 402S, 406P, 409G, 413I, 461Q, 464G, 465W, 468S, 472Y, 473S, 476A, 489T, 490V, 493M, 494N, 497G, 498Q, 501T
CDD
cd06174 (MFS)

Protein sequence

>MCA_03536_1
MGLDFLKKYKLPSIHLPQLPSLPPKIRKCFPHYKVIDEAAIAQVLAERNRQRRLAKGEKEEDIRITTYEEEEEDWEIRDE
ANRSKWNVFNEYEYKRASKTKHKWYHWFDQDDTPEERRLVIKLDIILTFFAFCMYWVKYLDQSNLNNAYVSGMKEDLGMK
GNDLVNTQAVYTVGSVVFQIPFMYMVHKYPTHIILPVMDIGWGFFTLAQYRAQSVGELQAYRFFVGVFESAFYPTIHYLF
GSWYKTNEYARRGGIYYFGQMLGILTAGLLQGAAYQNLHMTNGLEGWRWMMIINAIITIPIGIIGYWSLPGTPKDCYSIV
LNDEDLYVARKRFRDANIALEAEGPDFFSLSLWKGILSDWKFYGYVILNVFSWNTNNGTSGAYLLWLKSLNKYSVTKVNQ
LSAITPALGIVWIFLTGSFADLLRSRWGALMFSQSLNLLGNVMLAVWELPEGAIWFAFCLQYFGWAASCVNYSWAADGTR
HNPQVRAITVINMNMLGQASTAVTSVLVWKTVEAPRYLKGYSFTASATFAMMICACVILPLYKRDERKHAAENGILVYNS
ALGEEPPQIPTKSITNSNQIDNEKTGISTPDVVDVYSTSNSSSNNNNNDYSKDTIQYNDKI

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

None predicted.

Cellular Component

GO:0016021 integral component of membrane

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Entry type

Status

Per-residue features