Protein

MCA_03500_1

Length
515 amino acids

Gene name: ZWF1

Description: Glucose-6-phosphate 1-dehydrogenase

Browser: contigC:134183-135898-

RNA-seq: read pairs 24590, FPKM 588.8, percentile rank 94.9% (100% = highest expression)

Protein function

Annotation:ZWF1Glucose-6-phosphate 1-dehydrogenase
KEGG:K00036G6PD glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]
EGGNOG:0PHEKZWF1glucose-6-phosphate 1-dehydrogenase
SGD closest match:S000005185ZWF1Glucose-6-phosphate 1-dehydrogenase
CGD closest match:CAL0000192089ZWF1Glucose-6-phosphate 1-dehydrogenase

Protein alignments

%idAln lengthE-value
MIA_02877_183.11%5150.0MIA_02877_1
A0A0J9XGH3_GEOCN75.59%5120.0Glucose-6-phosphate 1-dehydrogenase OS=Geotrichum candidum GN=BN980_GECA16s00890g PE=3 SV=1
A0A1E3PSU7_9ASCO65.07%5010.0Glucose-6-phosphate 1-dehydrogenase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_49153 PE=3 SV=1
UniRef50_A0A084QFV864.46%4980.0Glucose-6-phosphate 1-dehydrogenase n=77 Tax=Sordariomycetes TaxID=147550 RepID=A0A084QFV8_9HYPO
Q6C4Y7_YARLI65.85%4920.0Glucose-6-phosphate 1-dehydrogenase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E22649g PE=3 SV=1
A0A167E3I9_9ASCO71.18%4510.0Glucose-6-phosphate 1-dehydrogenase OS=Sugiyamaella lignohabitans GN=ZWF1 PE=3 SV=1
A0A1E4TF38_9ASCO62.67%5010.0Glucose-6-phosphate 1-dehydrogenase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_106049 PE=3 SV=1
A0A060TD85_BLAAD62.27%4930.0Glucose-6-phosphate 1-dehydrogenase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D45936g PE=3 SV=1
A0A1D8PEG2_CANAL61.02%5080.0Glucose-6-phosphate 1-dehydrogenase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ZWF1 PE=3 SV=1
G6PD_YEAST60.00%4900.0Glucose-6-phosphate 1-dehydrogenase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ZWF1 PE=1 SV=4

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.5173

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 400 450 515

Detailed signature matches

  1. Family IPR001282
    Glucose-6-phosphate dehydrogenase
    1. PIRSF000110 (G6PD)
    2. TIGR00871
    3. PR00079 (G6PDHDRGNASE)
    4. MF_00966 (G6PD)
  2. Domain IPR016040
    NAD(P)-binding domain
    1. SSF51735 (NAD(P)-bi...)
  3. Domain IPR022674
    Glucose-6-phosphate dehydrogenase, NAD-binding
    1. PF00479 (G6PD_N)
  4. Domain IPR022675
    Glucose-6-phosphate dehydrogenase, C-terminal
    1. PF02781 (G6PD_C)
  5. SITE IPR019796
    Glucose-6-phosphate dehydrogenase, active site
    1. PS00069 (G6P_DEHYDR...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:3.30.36...
  3. G3DSA:3.40.50...
  4. SSF55347 (Glycerald...)

Protein sequence

>MCA_03500_1
MSLARRRSSSVGLSPVSATELTDSVTIVVFGASGDLAKKKTFPALFGLYKNGLLPKKFRIIGYARTNMSEEEFLDRITGY
IKLSPDDASASTKLEQFKELCSYVSGQYDTDEGFIKLSKKVEELENEMKVETRDRFFYFALPPSVFAEVSTHLKKNVYPG
DKGSVRVIIEKPFGRDLESSRALQSKLADVWEESEMFRIDHYLGKEMVKNILILRFGNIFFSSSWNKNTISNVQISFKEP
FGTEGRGGYFDNIGIIRDVMQNHLLQVLSLIAMERPVSFDSEDIRDEKVKVLKAIAPIEMENVILGQYDKSIDGTKPAYI
DDATVPKDSRAVTFAAISLAIHNERWEGVPFILRAGKALDEAKVEIRIQFKDVPRGIFQSIPRNELVIRVQPEEAIYLKM
NCKYPGLSTRTVPTDMDLTYHSRYANLKIPEAYEALILDALKGDHSNFVRDDELDVSWDLFTPLLKEIDENKSLIPEKYP
YGTRGPKSVSKFLADRGYIRDTAGLYQWPVTRGNL

GO term prediction

Biological Process

GO:0006006 glucose metabolic process
GO:0055114 oxidation-reduction process

Molecular Function

GO:0004345 glucose-6-phosphate dehydrogenase activity
GO:0050661 NADP binding

Cellular Component

None predicted.