Protein

MCA_03496_1

Length
448 amino acids

Gene name: TYR1

Description: Prephenate dehydrogenase [NADP(+)]

Browser: contigC:125876-127413-

RNA-seq: read pairs 889, FPKM 24.5, percentile rank 47.1% (100% = highest expression)

Protein function

Annotation:TYR1Prephenate dehydrogenase [NADP(+)]
KEGG:K00211TYR1 prephenate dehydrogenase (NADP+) [EC:1.3.1.13]
EGGNOG:0PGS8TYR1prephenate dehydrogenase
SGD closest match:S000000370TYR1Prephenate dehydrogenase [NADP(+)]
CGD closest match:CAL0000201106TYR1Prephenate dehydrogenase (NADP(+))

Protein alignments

%idAln lengthE-value
MIA_02872_179.29%4490.0MIA_02872_1
A0A0J9X4C0_GEOCN74.94%4310.0Similar to Saccharomyces cerevisiae YBR166C TYR1 Prephenate dehydrogenase involved in tyrosine biosynthesis OS=Geotrichum candidum GN=BN980_GECA01s08183g PE=4 SV=1
Q6C1B7_YARLI67.75%4310.0YALI0F17644p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F17644g PE=4 SV=1
A0A1E3PHM1_9ASCO69.66%4350.0Prephenate dehydrogenase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_51509 PE=4 SV=1
A0A060TDP4_BLAAD68.19%4150.0ARAD1D45738p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D45738g PE=4 SV=1
Q5AMP2_CANAL67.23%4120.0Prephenate dehydrogenase (NADP(+)) OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=TYR1 PE=4 SV=1
UniRef50_A0A074YID163.13%4150.0Uncharacterized protein n=13 Tax=Fungi TaxID=4751 RepID=A0A074YID1_9PEZI
TYR1_YEAST62.53%4430.0Prephenate dehydrogenase [NADP(+)] OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TYR1 PE=1 SV=2
A0A1E4TA11_9ASCO51.06%4231e-134Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_125622 PE=4 SV=1
A0A167CGK2_9ASCO67.38%2793e-124Pprephenate dehydrogenase (NADP(+)) OS=Sugiyamaella lignohabitans GN=TYR1 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.4590

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 400 448

Detailed signature matches

  1. Family IPR012385
    Prephenate dehydrogenase, fungal
    1. PIRSF036510 (PDH_fung)
  2. Domain IPR016040
    NAD(P)-binding domain
    1. SSF51735 (NAD(P)-bi...)
  3. Domain IPR003099
    Prephenate dehydrogenase
    1. PF02153 (PDH)
    2. PS51176 (PDH_ADH)
  4. Domain IPR008927
    6-phosphogluconate dehydrogenase C-terminal domain-like
    1. SSF48179 (6-phospho...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.10.36...
  2. G3DSA:3.40.50...

Protein sequence

>MCA_03496_1
MSVIRKGIKEFPPFDENQVQEWKKTKKIGIIGLGDMGRLYVNKFQSAGWKVCACDQESNYEKLKEEFKDSDLEIMKNGHY
VSRSCDFIIYSVEAENINKIVSMYGPSTKINAIVGGQTSCKAPEIKAFETYLPEDVEIITCHSLHGPKVPTEGQPLVLIQ
HRASDESFTFVRSIFREFKSKNVYLSAKEHDKITADTQAVTHAAFLSMGVAWKANQQYPWTVSRLVGGIENAKVNISLRI
YSNKWHVYAGLAITNPYAHPQILQYAQSVTALFKLIIEGKIDELRERLFAAREAIFGKLEKQHSLLLPDELLEKYSLGKL
PSKGSEVLNSHLSLLGIVDSWYQLGIVPYDHMICSTPLFRIWLGVTEYLFCTPGLLEECIEATKFNTFRGDDMEFCIAAR
TWSDIVLHGDFELYRATFEKTQKYFAPMFQEANKIGNEMIKEILKNTN

GO term prediction

Biological Process

GO:0006571 tyrosine biosynthetic process
GO:0055114 oxidation-reduction process

Molecular Function

GO:0004665 prephenate dehydrogenase (NADP+) activity
GO:0008977 prephenate dehydrogenase (NAD+) activity

Cellular Component

None predicted.