Protein

MCA_03488_1

Length
551 amino acids

Gene name: ECM14

Description: Putative metallocarboxypeptidase ECM14

Browser: contigC:104297-105953+

RNA-seq: read pairs 5063, FPKM 113.3, percentile rank 80.8% (100% = highest expression)

Protein function

Annotation:ECM14Putative metallocarboxypeptidase ECM14
KEGG:K08783ECM14 extracellular matrix protein 14 [EC:3.4.17.-]
EGGNOG:0PF8XECM14carboxypeptidase that may be involved in cell wall organization and biogenesis (By similarity)
SGD closest match:S000001174ECM14Putative metallocarboxypeptidase ECM14
CGD closest match:CAL0000185255ECM14Putative metallocarboxypeptidase

Protein alignments

%idAln lengthE-value
MIA_03270_165.05%4550.0MIA_03270_1
A0A0J9XI60_GEOCN59.23%4390.0Similar to Saccharomyces cerevisiae YHR132C ECM14 Putative metalloprotease with similarity to the zinc carboxypeptidase family, required for normal cell wall assembly OS=Geotrichum candidum GN=BN980_GECA20s00142g PE=3 SV=1
UniRef50_A0A0J9XI6059.23%4391e-180Similar to Saccharomyces cerevisiae YHR132C ECM14 Putative metalloprotease with similarity to the zinc carboxypeptidase family, required for normal cell wall assembly n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XI60_GEOCN
Q6CES8_YARLI50.22%4582e-148YALI0B13310p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B13310g PE=3 SV=1
A0A1E3PRI9_9ASCO51.03%4375e-145Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81126 PE=3 SV=1
ECM14_YEAST57.23%3186e-114Putative metallocarboxypeptidase ECM14 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ECM14 PE=1 SV=1
A0A1D8PJK3_CANAL42.79%4375e-113Putative metallocarboxypeptidase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ECM14 PE=4 SV=1
A0A167DZV3_9ASCO40.26%4672e-94Ecm14p OS=Sugiyamaella lignohabitans GN=ECM14 PE=4 SV=1
A0A1E4TK40_9ASCO36.95%4523e-90Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_713 PE=3 SV=1
A0A060T4M7_BLAAD34.32%4375e-53ARAD1C42130p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C42130g PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0842

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 551

Detailed signature matches

  1. Domain IPR003146
    Carboxypeptidase, activation peptide
    1. G3DSA:3.30.70...
  2. Domain IPR000834
    Peptidase M14, carboxypeptidase A
    1. PR00765 (CRBOXYPTASEA)
    2. PS00132 (CARBOXYPEP...)
    3. SM00631 (zn_carb)
    4. PF00246 (Peptidase_M14)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.63...
  2. NON_CYTOPLASM... (N...)
  3. SIGNAL_PEPTIDE (Sig...)
  4. SIGNAL_PEPTID... (S...)
  5. SIGNAL_PEPTID... (S...)
  6. SIGNAL_PEPTID... (S...)
  7. SSF53187 (Zn-depend...)
  8. SignalP-noTM
  9. TMhelix
  10. cd06248 (M14_CP_A-B...)

Residue annotation

  1. Zn binding site cd...
  2. putative active si...

Protein sequence

>MCA_03488_1
MVFYSKRALIVLGWLVVLCLATNVAAVSNQMLLVSQQEEISNNNNNNNNDNSETIEKSQSFINQQKSHGFGLFNWLKDTF
FGSIDNEQVILNNNNNNNKHSHTNEEEQQTIENDLNKVVSAMDFSQYENEVVLRFNWTSPREKRAFLKACKTLVLDVWKA
DVVSGDVRLHVSRVKNLLRLLPKSMRDKFSIMIPDLEHAVYATFPEVAAGGSSSSSSGSSNTDFLNKDMEFHAMSELFFK
DYRPLSAIYTWLDILEDTYPSQVRKEIIGKTHEGRDLRVYHLYSSKYDKQEPSGKKKTIIISSGAHAREWISVTTTLYVL
YQLLTNQKRLAERKILENLDFLIVPVLNPDGYQYTWEHDRLWRKNRQSTGVAICNGLDIDSSFPYHWAPSLGTPCSEGYA
GQEPLEALEAYHLTNYINKTSEKHKYFGYLDFHSYSQSILYPYGYSCDEEPRDKENLLELAYGMAKVIRWTSGKIYDVLP
LCHDREYDPEDGSGGCALDFMYKIHAIWAFQLKLRDTGNHGFLLPKKFIDPVGKEIYNSLKYFCDFILNPE

GO term prediction

Biological Process

GO:0006508 proteolysis

Molecular Function

GO:0004180 carboxypeptidase activity
GO:0004181 metallocarboxypeptidase activity
GO:0008270 zinc ion binding

Cellular Component

None predicted.