Protein

MCA_03475_1

Length
281 amino acids


Gene name: CDC8

Description: Thymidylate kinase

Browser: contigC:69161-70007-

RNA-seq: read pairs 903, FPKM 39.6, percentile rank 60.1% (100% = highest expression)

Protein function

Annotation:CDC8Thymidylate kinase
KEGG:K00943tmk dTMP kinase [EC:2.7.4.9]
EGGNOG:0PNUSCDC8thymidylate kinase
SGD closest match:S000003818CDC8Thymidylate kinase
CGD closest match:CAL0000197535orf19.1137Bifunctional thymidylate/uridylate kinase

Protein alignments

%idAln lengthE-value
MIA_00184_142.50%2406e-46MIA_00184_1
A0A167EP69_9ASCO37.02%2085e-31Bifunctional thymidylate/uridylate kinase OS=Sugiyamaella lignohabitans GN=CDC8 PE=3 SV=1
UniRef50_A0A0F7SFT834.27%2482e-27Thymidylate kinase/adenylate kinase n=1 Tax=Phaffia rhodozyma TaxID=264483 RepID=A0A0F7SFT8_PHARH
A0A1E3PJT5_9ASCO35.57%2533e-30Thymidylate kinase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_50974 PE=3 SV=1
A0A0J9XCE1_GEOCN43.27%2087e-29Similar to Saccharomyces cerevisiae YJR057W CDC8 Thymidylate and uridylate kinase OS=Geotrichum candidum GN=BN980_GECA10s01308g PE=3 SV=1
A0A060THF9_BLAAD32.56%2581e-27ARAD1D38280p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D38280g PE=3 SV=1
A0A1E4TAD4_9ASCO30.89%2598e-27Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_127761 PE=3 SV=1
Q6CC22_YARLI33.82%2072e-26YALI0C13354p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C13354g PE=3 SV=1
Q59TV7_CANAL35.61%2642e-21Bifunctional thymidylate/uridylate kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.1137 PE=3 SV=1
KTHY_YEAST33.97%2093e-21Thymidylate kinase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CDC8 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.6028

Protein family membership

Domains and repeats

1 50 100 150 200 250 281

Detailed signature matches

    1. MF_00165 (Thymidyla...)
    1. SSF52540 (P-loop co...)
    1. PS01331 (THYMIDYLAT...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. PF02223 (Thymidylat...)

Protein sequence

>MCA_03475_1
MIGRGLLILIEGLDRSGKSTQCQMLAESFDSILQEVFTALERDQKEEQLGSNAAALVMRFPNRTTQIGSILNSYLQGSSS
KASSTDNKESSLYISKLSTLRSNHLLFSANRWECLPEIHSTLERGTSIILDRYIYSGIAYSYAAYQALNSEFKKSLIPDG
NHNKNFPGWLHTPDLGLPIPDITLFLTVDQKTAQARAGFGAERYETTDIQRFVAKCFTEILAVSHKEHQDKDLCPWIEIP
TDGCDQEQVHFKIRQIVKELLFNWEKLNDQMKKIQTYETIL

GO term prediction

Biological Process

GO:0006233 dTDP biosynthetic process

Molecular Function

GO:0004798 thymidylate kinase activity
GO:0005524 ATP binding

Cellular Component

None predicted.