Protein

MCA_03474_1

Length
660 amino acids

Gene name: CBK1

Description: Serine/threonine-protein kinase Cbk1; in S. cerevisiae it is involved in regulation of cellular morphogenesis, polarized growth, and septum destruction.

Browser: contigC:66977-68960+

RNA-seq: read pairs 5537, FPKM 103.5, percentile rank 79.4% (100% = highest expression)

Protein function

Annotation:CBK1Serine/threonine-protein kinase Cbk1; in S. cerevisiae it is involved in regulation of cellular morphogenesis, polarized growth, and septum destruction.
KEGG:K08286E2.7.11.- protein-serine/threonine kinase [EC:2.7.11.-]
EGGNOG:0PIR4CBK1serine threonine-protein kinase
SGD closest match:S000005105CBK1Serine/threonine-protein kinase CBK1
CGD closest match:CAL0000198853CBK1Serine/threonine-protein kinase CBK1

Protein alignments

%idAln lengthE-value
MIA_00183_187.84%4770.0MIA_00183_1
A0A0J9XD26_GEOCN86.95%4750.0Similar to Saccharomyces cerevisiae YNL161W CBK1 Serine/threonine protein kinase that regulates cell morphogenesis pathways OS=Geotrichum candidum GN=BN980_GECA10s01297g PE=4 SV=1
A0A167EP29_9ASCO78.16%4990.0Serine/threonine protein kinase CBK1 OS=Sugiyamaella lignohabitans GN=CBK1 PE=4 SV=1
A0A060TCS2_BLAAD80.21%4800.0ARAD1D38236p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D38236g PE=4 SV=1
CBK1_CANAL72.45%4900.0Serine/threonine-protein kinase CBK1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CBK1 PE=1 SV=2
UniRef50_Q5AP5372.45%4900.0Serine/threonine-protein kinase CBK1 n=87 Tax=Dikarya TaxID=451864 RepID=CBK1_CANAL
CBK1_YEAST69.57%4930.0Serine/threonine-protein kinase CBK1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CBK1 PE=1 SV=1
A0A1E4TAL5_9ASCO73.08%4830.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_28758 PE=4 SV=1
CBK1_YARLI68.05%4820.0Serine/threonine-protein kinase CBK1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=CBK1 PE=3 SV=1
A0A1E3PIH4_9ASCO73.39%3870.0YNL161Wp-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_35068 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0080

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 660

Detailed signature matches

  1. Domain IPR011009
    Protein kinase-like domain
    1. SSF56112 (Protein k...)
  2. Domain IPR000719
    Protein kinase domain
    1. PS50011 (PROTEIN_KI...)
    2. SM00220 (serkin_6)
    3. PF00069 (Pkinase)
  3. Domain IPR000961
    AGC-kinase, C-terminal
    1. SM00133 (pkinase_C_6)
    2. PS51285 (AGC_KINASE...)
  4. SITE IPR017441
    Protein kinase, ATP binding site
    1. PS00107 (PROTEIN_KI...)
  5. SITE IPR008271
    Serine/threonine-protein kinase, active site
    1. PS00108 (PROTEIN_KI...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:1.10.51...
  3. G3DSA:3.30.20...
  4. PF12330 (Haspin_kinase)
  5. PIRSF000654 (ILK)
  6. mobidb-lite (disord...)

Protein sequence

>MCA_03474_1
MYQQQGNNSGFFYQQQQQQGQPQAQQQFYSTVAPPPSAYTQFYKQQPSQASSHSLTSNPNNNGLGQQNAGINAPPAPFLQ
VPTPSQTALLTNQRIAQGYTQQPMYYTPQQLHEQQMLIQQQQQRLYQQQQQQQYQYQQQQQQQQQQLLKQQQQQQQQQQQ
QQQQQQQQQQQQKTAEQQRNQQKPEINGDYVYLERHPEQFSKATQEKANAVKAKIEHYFQINVAHAVERNQRRVMCEQSL
AQERSSEERKNRTLASLGKKESNFLRLRRTRLSLDDFITVKVIGKGAFGEVRLVQKRDTGKIYAMKTLLKSEMYSKDQLA
HVKAERDVLAGADSPWVVALYYSFQDSQYLYLIMEFLPGGDLMTMLIKYDVFSEDITRFYIAECVLAIEAIHNLGFIHRD
IKPDNILIDKTGHIKLSDFGLSTGLQKQHDSNYYRKLLDKDPPANQRNSLMVDPIHLTISNRQQISTWRKSRRMMAYSTV
GTPDYIAPEIFIHQGYSQECDWWSLGAIMFECLVGWPPFCSETPQETYRKIIHWQESLQFPDDVHLSQESEDLIRQFLTS
ADRRIGRNGAAEIKAHPFFRGVDWDSIREFNAPFIPKLSSITDTSYFSTEEFDQIPDGPPSNPAGNAGDSNGDGRDARID
LPFIGYTFSRFDYLTKKNAL

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding

Cellular Component

None predicted.