Protein

MCA_03464_1

Length
842 amino acids


Description: Protein with copper fist DNA-binding domain

Browser: contigC:45746-48424+

RNA-seq: read pairs 5196, FPKM 76.2, percentile rank 74.4% (100% = highest expression)

Protein function

Annotation:Protein with copper fist DNA-binding domain
EGGNOG:0PMZKPGUG_05595copper ion binding
SGD closest match:S000006212HAA1Transcriptional activator HAA1
CGD closest match:CAL0000185450CUP2Cup2p

Protein alignments

%idAln lengthE-value
MIA_06207_181.40%863e-44MIA_06207_1
A0A0J9XDM0_GEOCN79.07%863e-42Uncharacterized protein OS=Geotrichum candidum GN=BN980_GECA10s04113g PE=4 SV=1
UniRef50_A0A0J9XDM079.07%866e-39Uncharacterized protein n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XDM0_GEOCN
A0A060T3L4_BLAAD67.44%862e-35ARAD1C34672p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C34672g PE=4 SV=1
CRF1_YARLI75.32%777e-34Copper resistance protein CRF1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=CRF1 PE=4 SV=1
A0A161HKY0_9ASCO65.17%893e-33Haa1p OS=Sugiyamaella lignohabitans GN=HAA1 PE=4 SV=1
Q5AKX6_CANAL63.53%853e-29Cup2p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CUP2 PE=4 SV=1
A0A1E3PDE3_9ASCO63.33%902e-30Copper-fist-domain-containing protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_38687 PE=4 SV=1
HAA1_YEAST51.61%932e-23Transcriptional activator HAA1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HAA1 PE=1 SV=1
A0A1E4THJ2_9ASCO50.60%835e-23Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_31938 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2700

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 842

Detailed signature matches

    1. SM00412 (copper1)
    2. SM01090 (Copper_fist_2)
    3. PF00649 (Copper-fist)
    4. PR00617 (COPPERFIST)
    5. SSF57879 (Zinc doma...)
    6. PS50073 (COPPER_FIST_2)
Unintegrated signatures no IPR
Unintegrated signatures
  1. mobidb-lite (disord...)

Protein sequence

>MCA_03464_1
MVYIDGVKYACERCIRGHRVTGCNHTNMPLTMIKPKGRPATQCAHCREARKNKQSHVKCKCGTGLSSNGKHSATCPCTLD
KELCTCSKNKNKSNNNKNTQICSSSSNKAKKSSLDSVSTKKSMASITKSKKHAKSNSSASISSITSSSSNANTTSTPPLP
IPLIPSTTSISSLLDATSLSPSLTNTGGALSGIFSSSPSMPPYMSSPTMTGSSPSSSSILKSVSSCASLASLNNSGSTNN
TNGSRRARKTLAASRGPIIHPASSASLSAKINALNHLDPTPSPPDDGLDAVSFYSDNSSSINSNTNNNNISLNMNNNNSN
NNINKNDNSDQVTMFFNLINSEPTSKPNGDLLNSLDSIPFNNNLPTNAANDGSNYYENMNKISSNTLIPSSSSSSLAQEY
SFQSNNTSSQLGGNYSNSPFSSSFMTEARYDGYVSDADPPLQFNVAHKYRLPQSDRKPNNQSNNNNNNSKLDNEILEPLR
NKTLANSFTGSISTSNNSNNSNNNNNSHIGEVIVRPGVMDDFTLLSPDDNYEVLKNSATSKGLLDLVDENSPNSFNGSSS
VSSSDAGSLFDYTSKGNNNNNNYNTNEFEKQTSFYNNDSNFMMIPPNTAESSVPLYPILTANRPQKKETDLTLVLKTNGG
DSENFNYNNNNNKNDGSLFLSSNIPYSSSSSSSSPSSNNNNNNNNQIFNNNNNGDAFSSNSTATSTSLSTTPQTPEQFDL
VRTQNQIFNNFADNNNNNNGNNSLSNNGAAPDDFFPLNLDISDLTSAPLEQFQQQIRKQNLNSIKPKMTADDTIDFDLAA
DEGNDMNFLNNNTNNNNAMILNGFTNDNNDNNGLYDLVTFKD

GO term prediction

Biological Process

GO:0006355 regulation of transcription, DNA-templated

Molecular Function

GO:0003677 DNA binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0005507 copper ion binding

Cellular Component

GO:0005634 nucleus