Protein

MCA_03439_1

Length
551 amino acids

Gene name: SAL1

Description: mitochondrial Mg-ATP/Pi transporter; solute carrier family 25 member 23/24/25/41; protein with calcium-binding domain

Browser: contigB:4429648-4431360-

RNA-seq: read pairs 2295, FPKM 51.4, percentile rank 66.0% (100% = highest expression)

Protein function

Annotation:SAL1mitochondrial Mg-ATP/Pi transporter; solute carrier family 25 member 23/24/25/41; protein with calcium-binding domain
KEGG:K14684SLC25A23S solute carrier family 25 (mitochondrial phosphate transporter), member 23/24/25/41
EGGNOG:0PHDSPGUG_01966Mitochondrial carrier
SGD closest match:S000005027SAL1Truncated non-functional calcium-binding mitochondrial carrier SAL1-1
CGD closest match:CAL0000200520orf19.1403Ca(2+)-binding ATP:ADP antiporter

Protein alignments

%idAln lengthE-value
MIA_05627_170.51%5460.0MIA_05627_1
A0A0J9XER0_GEOCN61.93%5490.0Similar to Saccharomyces cerevisiae YNL083W SAL1 ADP/ATP transporter, member of the Ca2+-binding subfamily of mitochondrial carriers OS=Geotrichum candidum GN=BN980_GECA12s02309g PE=3 SV=1
UniRef50_A0A0J9X3V562.31%5360.0Similar to Saccharomyces cerevisiae YNL083W SAL1 ADP/ATP transporter, member of the Ca2+-binding subfamily of mitochondrial carriers n=3 Tax=Saccharomycetales TaxID=4892 RepID=A0A0J9X3V5_GEOCN
A0A161HGG6_9ASCO60.42%4750.0Ca(2+)-binding ATP:ADP antiporter SAL1 OS=Sugiyamaella lignohabitans GN=SAL1 PE=3 SV=1
Q6C6B6_YARLI50.82%5517e-177YALI0E10813p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E10813g PE=3 SV=1
A0A060T921_BLAAD52.17%5312e-173ARAD1D12078p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D12078g PE=3 SV=1
A0A1E3PFY0_9ASCO49.54%5452e-169Mitochondrial carrier OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_84117 PE=3 SV=1
A0A1E4TIF9_9ASCO48.04%5372e-154Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_72567 PE=3 SV=1
Q59YC3_CANAL44.49%5351e-137Ca(2+)-binding ATP:ADP antiporter OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.1403 PE=3 SV=1
CMC1_YEAST33.69%4635e-76Truncated non-functional calcium-binding mitochondrial carrier SAL1-1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SAL1 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0115

Protein family membership

Domains and repeats

  1. Domain
  2. Repeat
1 100 200 300 400 500 551

Detailed signature matches

  1. Family IPR002067
    Mitochondrial carrier protein
    1. PR00926 (MITOCARRIER)
  2. Domain IPR011992
    EF-hand domain pair
    1. SSF47473 (EF-hand)
  3. Domain IPR002048
    EF-hand domain
    1. PF13499 (EF-hand_7)
    2. cd00051 (EFh)
    3. SM00054 (efh_1)
    4. PS50222 (EF_HAND_2)
    5. PF13833 (EF-hand_8)
  4. Domain IPR023395
    Mitochondrial carrier domain
    1. G3DSA:1.50.40.10
    2. SSF103506 (Mitochon...)
  5. Repeat IPR018108
    Mitochondrial substrate/solute carrier
    1. PS50920 (SOLCAR)
    2. PF00153 (Mito_carr)
  6. SITE IPR018247
    EF-Hand 1, calcium-binding site
    1. PS00018 (EF_HAND_1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. Coil
  3. G3DSA:1.10.23...
  4. NON_CYTOPLASM... (N...)
  5. TMhelix
  6. TRANSMEMBRANE (Tran...)

Residue annotation

  1. Ca2+ binding site ...

Protein sequence

>MCA_03439_1
MHHIAHSEEDQQYLKNMIGHPEERERRTERLFQTLDNSKTGILSSDTLLESFREQYNPLPLSEESIENLISTIAPENRGY
LSYEDFKNYIYSIEQDIVASFKALDTKRDGKLDFEELRDGLERLGIEIDDERAELFFNILDTDEDGFISYEEWVQFLLFV
PLNSDDKVVPLQAAYEFFVEELDLSSEGDFFLSSETLNGFGYFLAGGFAGVVSRTCTAPFDRLKVYLIASSGKVPPVATS
SKPSISPNPKQDIKASTSKALKTALSLQKSSKQLVAEAAEATSAVAAQESQGQLMRALKHLWSQGGIRAFFVGNGLNVIK
VFPESAMKFGTFETVKRFFAQLEGVEDTSEISRLATFISGGLGGVVAQFTVYPIDTLKFRIQCEAQFSKLRGNQLLFETA
SNMWKDGGLRMFYRGIIVGVCGIFPFAALDLGTFAAMKRALIAREAHKRGVDVSEVRLGNLTVLTMGAMSGCVGASVVYP
INLLRTRLQAQGTHAHPYTYTGLIDVYQKTVARDGYRGLWRGLLPNLAKVAPAVSISYLTYENLKSFLNLA

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

GO:0005509 calcium ion binding

Cellular Component

None predicted.