Protein

MCA_03435_1

Length
769 amino acids

Gene name: TUL1

Description: subunit of the DSC ubiquitin ligase complex; protein with Zn-finger RING/FYVE/PHD-type domain

Browser: contigB:4418752-4421062+

RNA-seq: read pairs 1371, FPKM 22.0, percentile rank 43.9% (100% = highest expression)

Protein function

Annotation:TUL1subunit of the DSC ubiquitin ligase complex; protein with Zn-finger RING/FYVE/PHD-type domain
EGGNOG:0PISQFG07178.1RING finger ubiquitin ligase
SGD closest match:S000001517TUL1Transmembrane E3 ubiquitin-protein ligase 1
CGD closest match:CAL0000184186orf19.2131Ubiquitin-protein ligase

Protein alignments

%idAln lengthE-value
MIA_00157_155.65%8230.0MIA_00157_1
A0A0J9X606_GEOCN43.79%7810.0Similar to Saccharomyces cerevisiae YKL034W TUL1 Golgi-localized RING-finger ubiquitin ligase (E3) OS=Geotrichum candidum GN=BN980_GECA02s07270g PE=4 SV=1
UniRef50_A0A0J9X60643.79%7810.0Similar to Saccharomyces cerevisiae YKL034W TUL1 Golgi-localized RING-finger ubiquitin ligase (E3) n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X606_GEOCN
A0A161HLC3_9ASCO37.94%7593e-173Ubiquitin-protein ligase TUL1 OS=Sugiyamaella lignohabitans GN=TUL1 PE=4 SV=1
A0A060SZ38_BLAAD36.22%7981e-170ARAD1A17116p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A17116g PE=4 SV=1
A0A1E3PN60_9ASCO36.91%6158e-135Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_69797 PE=4 SV=1
Q6C0G6_YARLI31.46%7283e-106YALI0F24915p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F24915g PE=4 SV=1
A0A1D8PQF4_CANAL29.56%8121e-86Ubiquitin-protein ligase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.2131 PE=4 SV=1
TUL1_YEAST30.72%6252e-86Transmembrane E3 ubiquitin-protein ligase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TUL1 PE=1 SV=1
A0A1E4TBJ1_9ASCO28.53%7089e-84Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_58134 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2757
Predicted cleavage: 46

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 769

Detailed signature matches

  1. Domain IPR013083
    Zinc finger, RING/FYVE/PHD-type
    1. G3DSA:3.30.40.10
  2. Domain IPR001841
    Zinc finger, RING-type
    1. SM00184 (ring_2)
    2. PS50089 (ZF_RING_2)
  3. Domain IPR024766
    Zinc finger, RING-H2-type
    1. PF12678 (zf-rbx1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. NON_CYTOPLASM... (N...)
  3. SIGNAL_PEPTIDE (Sig...)
  4. SIGNAL_PEPTID... (S...)
  5. SIGNAL_PEPTID... (S...)
  6. SIGNAL_PEPTID... (S...)
  7. SSF57850 (RING/U-box)
  8. SignalP-noTM
  9. TMhelix
  10. TRANSMEMBRANE (Tran...)
  11. cd16448 (RING-H2)
  12. mobidb-lite (disord...)

Residue annotation

  1. Zn binding site cd...

Protein sequence

>MCA_03435_1
MEFNRSVFLFLLLFLFFFKPAGNPPRLTTPNERHLISSYISLQRNDTLLLQKSTFGNVPGNITGISMKNGHFVPTSVQSL
AHNILFSETLDNSNHNKHVFYSNYSGIYTGKWSKLKNGQDVSPRKMEIPSIFDLNPSDEDNIFSNNPRMPSKKVLFSEQV
KENITEEDGKFSLSIDEIIPRDRKNPNVTIMKMEIAIQDVEESVQYNLYLTGLHIRPTGNVILSTSSLKYSGLQYLPHLI
MDETYFEESKSLMVRYLNTTLAIFKEDNDYLLFEDEMIAAQSCEFIFYGHFQSSNISKHDLNDIEDEIRNPVGRPHKPIP
QMRFSSLIYSPDCAFVLDSENAKGEKYEIYWKRIRTMIGASVALLVVQAYLMANQMKDTNTPSYLCKVSFYTIAMMSIVD
GSIWVASFASSFIEGLALPFMAIAFLSFALTSMFEMRYLAKIYQSQLTERQADARVRATFSGSNAVPTFVVRPDGSFESP
SPTPQPNAQNSQSPPTSLPTTETQSEIREEDLSERAIGSKIYSWFYFALLGFVICSLVAATWPISYRRKYEFTVIMCLYS
IWVPQIERNIARGFRRSFLWSFIIGTSIVRLIPVLYFTLNKHNILRHHYDPFLAICVSSWLVFQVLILYTQNVFGPRFFL
PRGYLPVLYDYHPILTQGDIETGISDIPSAAKDASAPLLSSSLPVKPLTNSHDHISKPTVDCAICMTPVELVITSKNSSP
ALVSSPALILARRKYMVTPCRHVFHTECMEQWMRTRLQCPICRNPLPPV

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0008270 zinc ion binding

Cellular Component

None predicted.