MCA_03430_1

Protein

Length

1,999 amino acids

Gene name: RIM15

Description: Serine/threonine-protein kinase Rim15; in S. cerevisiae involved in cell proliferation in response to nutrients.

Browser: contigB:4403276-4409459-

RNA-seq: read pairs 546, FPKM 3.4, percentile rank 14.5% (100% = highest expression)

Protein function

Annotation:		RIM15	Serine/threonine-protein kinase Rim15; in S. cerevisiae involved in cell proliferation in response to nutrients.
KEGG:	K12767	RIM15	serine/threonine-protein kinase RIM15 [EC:2.7.11.1]
EGGNOG:	0QED5	RIM15	serine threonine protein kinase
SGD closest match:	S000001861	RIM15	Serine/threonine-protein kinase RIM15
CGD closest match:	CAL0000180445	RIM15	Protein kinase

Protein alignments

	%id	Aln length	E-value
A0A0J9XDU6_GEOCN	52.05%	707	0.0	Similar to Saccharomyces cerevisiae YFL033C RIM15 Glucose-repressible protein kinase involved in signal transduction during cell proliferation in response to nutrients OS=Geotrichum candidum GN=BN980_GECA11s01363g PE=4 SV=1
UniRef50_A0A0J9XDU6	52.05%	707	0.0	Similar to Saccharomyces cerevisiae YFL033C RIM15 Glucose-repressible protein kinase involved in signal transduction during cell proliferation in response to nutrients n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XDU6_GEOCN
MIA_04240_1	53.65%	425	5e-108	MIA_04240_1
A0A060T1U4_BLAAD	58.95%	285	1e-91	ARAD1C27148p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C27148g PE=4 SV=1
A0A161HF00_9ASCO	72.77%	191	6e-84	Protein kinase RIM15 OS=Sugiyamaella lignohabitans GN=RIM15 PE=4 SV=1
Q6C1N7_YARLI	74.25%	167	2e-76	YALI0F14707p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F14707g PE=4 SV=1
A0A1D8PQP3_CANAL	67.76%	183	3e-74	Protein kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=RIM15 PE=4 SV=1
RIM15_YEAST	66.67%	177	4e-71	Serine/threonine-protein kinase RIM15 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RIM15 PE=1 SV=1
A0A1E4TF46_9ASCO	74.17%	151	2e-72	Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_12401 PE=4 SV=1
A0A1E3PH49_9ASCO	66.88%	154	1e-61	Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83629 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0066

Protein family membership

None predicted.

Domains and repeats

Domain
92 - 158
PAS domain (IPR000014)
1,425 - 1,503
AGC-kinase, C-terminal (IPR000961)
1,793 - 1,915
CheY-like superfamily (IPR011006)
Signal transduction response regulator, receiver domain (IPR001789)
Domain
929 - 1,456
Protein kinase-like domain (IPR011009)
Protein kinase domain (IPR000719)

1 200 400 600 800 1000 1200 1400 1600 1800 1999

Detailed signature matches

IPR000014

PAS domain
1. SSF55785 (PYP-like ...)
  
  92 - 158
  
  SUPERFAMILY
  SSF55785 (PYP-like sensor domain (PAS domain))
2. PS50112 (PAS)
  
  98 - 148
  
  PROSITE profiles
  PS50112 (PAS)
IPR011009

Protein kinase-like domain
1. SSF56112 (Protein k...)
  
  1,306 - 1,456
  
  SUPERFAMILY
  SSF56112 (Protein kinase-like (PK-like))
  
  929 - 1,092
  
  SUPERFAMILY
  SSF56112 (Protein kinase-like (PK-like))
IPR000719

Protein kinase domain
1. PS50011 (PROTEIN_KI...)
  
  946 - 1,424
  
  PROSITE profiles
  PS50011 (PROTEIN_KINASE_DOM)
2. PF00069 (Pkinase)
  
  1,311 - 1,424
  
  Pfam
  PF00069 (Pkinase)
  
  946 - 1,094
  
  Pfam
  PF00069 (Pkinase)
3. SM00220 (serkin_6)
  
  946 - 1,424
  
  SMART
  SM00220 (serkin_6)
IPR000961

AGC-kinase, C-terminal
1. PS51285 (AGC_KINASE...)
  
  1,425 - 1,503
  
  PROSITE profiles
  PS51285 (AGC_KINASE_CTER)
IPR011006

CheY-like superfamily
1. SSF52172 (CheY-like)
  
  1,793 - 1,915
  
  SUPERFAMILY
  SSF52172 (CheY-like)
IPR001789

Signal transduction response regulator, receiver domain
1. PS50110 (RESPONSE_R...)
  
  1,796 - 1,914
  
  PROSITE profiles
  PS50110 (RESPONSE_REGULATORY)
2. PF00072 (Response_reg)
  
  1,797 - 1,910
  
  Pfam
  PF00072 (Response_reg)
3. cd00156 (REC)
  
  1,798 - 1,913
  
  CDD
  cd00156 (REC)
4. SM00448 (REC_2)
  
  1,795 - 1,910
  
  SMART
  SM00448 (REC_2)
IPR008271

Serine/threonine-protein kinase, active site
1. PS00108 (PROTEIN_KI...)
  
  1,066 - 1,078
  
  PROSITE patterns
  PS00108 (PROTEIN_KINASE_ST)

no IPR

Unintegrated signatures

Coil

64 - 84

COILS
Coil (Coil)

558 - 578

COILS
Coil (Coil)
G3DSA:1.10.51...

1,043 - 1,505

GENE3D
G3DSA:1.10.510.10 (G3DSA:1.10.510.10)
G3DSA:3.30.20...

879 - 1,042

GENE3D
G3DSA:3.30.200.20 (G3DSA:3.30.200.20)
G3DSA:3.30.45...

74 - 589

GENE3D
G3DSA:3.30.450.20 (G3DSA:3.30.450.20)
G3DSA:3.40.50...

1,777 - 1,920

GENE3D
G3DSA:3.40.50.2300 (G3DSA:3.40.50.2300)
cd05579 (STKc_MAST_...)

952 - 1,429

CDD
cd05579 (STKc_MAST_like)
mobidb-lite (disord...)

1,200 - 1,228

MobiDB Lite
mobidb-lite (disorder_prediction)

412 - 464

MobiDB Lite
mobidb-lite (disorder_prediction)

1 - 52

MobiDB Lite
mobidb-lite (disorder_prediction)

538 - 594

MobiDB Lite
mobidb-lite (disorder_prediction)

1,245 - 1,303

MobiDB Lite
mobidb-lite (disorder_prediction)

818 - 904

MobiDB Lite
mobidb-lite (disorder_prediction)

667 - 689

MobiDB Lite
mobidb-lite (disorder_prediction)

480 - 499

MobiDB Lite
mobidb-lite (disorder_prediction)

1,438 - 1,552

MobiDB Lite
mobidb-lite (disorder_prediction)

1,940 - 1,999

MobiDB Lite
mobidb-lite (disorder_prediction)

1,584 - 1,708

MobiDB Lite
mobidb-lite (disorder_prediction)

1,720 - 1,741

MobiDB Lite
mobidb-lite (disorder_prediction)

175 - 228

MobiDB Lite
mobidb-lite (disorder_prediction)

1,106 - 1,176

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

ATP binding site c...

952I

ATP binding site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,025E, 1,026Y, 1,027L, 1,031D, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D
CDD
cd05579 (STKc_MAST_like)

953S

ATP binding site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,025E, 1,026Y, 1,027L, 1,031D, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D
CDD
cd05579 (STKc_MAST_like)

954R

ATP binding site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,025E, 1,026Y, 1,027L, 1,031D, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D
CDD
cd05579 (STKc_MAST_like)

955G

ATP binding site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,025E, 1,026Y, 1,027L, 1,031D, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D
CDD
cd05579 (STKc_MAST_like)

956A

ATP binding site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,025E, 1,026Y, 1,027L, 1,031D, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D
CDD
cd05579 (STKc_MAST_like)

960V

ATP binding site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,025E, 1,026Y, 1,027L, 1,031D, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D
CDD
cd05579 (STKc_MAST_like)

973A

ATP binding site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,025E, 1,026Y, 1,027L, 1,031D, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D
CDD
cd05579 (STKc_MAST_like)

975K

ATP binding site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,025E, 1,026Y, 1,027L, 1,031D, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D
CDD
cd05579 (STKc_MAST_like)

1,008A

ATP binding site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,025E, 1,026Y, 1,027L, 1,031D, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D
CDD
cd05579 (STKc_MAST_like)

1,025E

ATP binding site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,025E, 1,026Y, 1,027L, 1,031D, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D
CDD
cd05579 (STKc_MAST_like)

1,026Y

ATP binding site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,025E, 1,026Y, 1,027L, 1,031D, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D
CDD
cd05579 (STKc_MAST_like)

1,027L

ATP binding site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,025E, 1,026Y, 1,027L, 1,031D, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D
CDD
cd05579 (STKc_MAST_like)

1,031D

ATP binding site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,025E, 1,026Y, 1,027L, 1,031D, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D
CDD
cd05579 (STKc_MAST_like)

1,070D

ATP binding site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,025E, 1,026Y, 1,027L, 1,031D, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D
CDD
cd05579 (STKc_MAST_like)

1,072K

ATP binding site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,025E, 1,026Y, 1,027L, 1,031D, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D
CDD
cd05579 (STKc_MAST_like)

1,074D

ATP binding site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,025E, 1,026Y, 1,027L, 1,031D, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D
CDD
cd05579 (STKc_MAST_like)

1,075N

ATP binding site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,025E, 1,026Y, 1,027L, 1,031D, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D
CDD
cd05579 (STKc_MAST_like)

1,077L

ATP binding site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,025E, 1,026Y, 1,027L, 1,031D, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D
CDD
cd05579 (STKc_MAST_like)

1,087T

ATP binding site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,025E, 1,026Y, 1,027L, 1,031D, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D
CDD
cd05579 (STKc_MAST_like)

1,088D

ATP binding site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,025E, 1,026Y, 1,027L, 1,031D, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D
CDD
cd05579 (STKc_MAST_like)
active site cd05579

952I

active site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,024M, 1,025E, 1,027L, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)

953S

active site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,024M, 1,025E, 1,027L, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)

954R

active site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,024M, 1,025E, 1,027L, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)

955G

active site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,024M, 1,025E, 1,027L, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)

956A

active site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,024M, 1,025E, 1,027L, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)

960V

active site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,024M, 1,025E, 1,027L, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)

973A

active site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,024M, 1,025E, 1,027L, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)

975K

active site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,024M, 1,025E, 1,027L, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)

1,008A

active site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,024M, 1,025E, 1,027L, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)

1,024M

active site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,024M, 1,025E, 1,027L, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)

1,025E

active site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,024M, 1,025E, 1,027L, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)

1,027L

active site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,024M, 1,025E, 1,027L, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)

1,031D

active site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,024M, 1,025E, 1,027L, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)

1,033A

active site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,024M, 1,025E, 1,027L, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)

1,070D

active site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,024M, 1,025E, 1,027L, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)

1,072K

active site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,024M, 1,025E, 1,027L, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)

1,074D

active site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,024M, 1,025E, 1,027L, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)

1,075N

active site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,024M, 1,025E, 1,027L, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)

1,077L

active site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,024M, 1,025E, 1,027L, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)

1,087T

active site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,024M, 1,025E, 1,027L, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)

1,088D

active site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,024M, 1,025E, 1,027L, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)

1,096L

active site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,024M, 1,025E, 1,027L, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)

1,317F

active site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,024M, 1,025E, 1,027L, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)

1,318V

active site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,024M, 1,025E, 1,027L, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)

1,319G

active site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,024M, 1,025E, 1,027L, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)

1,320T

active site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,024M, 1,025E, 1,027L, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)

1,321P

active site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,024M, 1,025E, 1,027L, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)

1,322D

active site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,024M, 1,025E, 1,027L, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)

1,349E

active site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,024M, 1,025E, 1,027L, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)

1,355P

active site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,024M, 1,025E, 1,027L, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)

1,358H

active site
952I, 953S, 954R, 955G, 956A, 960V, 973A, 975K, 1,008A, 1,024M, 1,025E, 1,027L, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,075N, 1,077L, 1,087T, 1,088D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)
polypeptide substr...

956A

polypeptide substrate binding site
956A, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)

1,031D

polypeptide substrate binding site
956A, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)

1,033A

polypeptide substrate binding site
956A, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)

1,070D

polypeptide substrate binding site
956A, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)

1,072K

polypeptide substrate binding site
956A, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)

1,074D

polypeptide substrate binding site
956A, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)

1,096L

polypeptide substrate binding site
956A, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)

1,317F

polypeptide substrate binding site
956A, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)

1,318V

polypeptide substrate binding site
956A, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)

1,319G

polypeptide substrate binding site
956A, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)

1,320T

polypeptide substrate binding site
956A, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)

1,321P

polypeptide substrate binding site
956A, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)

1,322D

polypeptide substrate binding site
956A, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)

1,349E

polypeptide substrate binding site
956A, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)

1,355P

polypeptide substrate binding site
956A, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)

1,358H

polypeptide substrate binding site
956A, 1,031D, 1,033A, 1,070D, 1,072K, 1,074D, 1,096L, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D, 1,349E, 1,355P, 1,358H
CDD
cd05579 (STKc_MAST_like)
activation loop (A...

1,087T

activation loop (A-loop)
1,087T, 1,088D, 1,089F, 1,095G, 1,096L, 1,135S, 1,136S, 1,137L, 1,138G, 1,139S, 1,215Y, 1,275N, 1,276N, 1,316K, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D
CDD
cd05579 (STKc_MAST_like)

1,088D

activation loop (A-loop)
1,087T, 1,088D, 1,089F, 1,095G, 1,096L, 1,135S, 1,136S, 1,137L, 1,138G, 1,139S, 1,215Y, 1,275N, 1,276N, 1,316K, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D
CDD
cd05579 (STKc_MAST_like)

1,089F

activation loop (A-loop)
1,087T, 1,088D, 1,089F, 1,095G, 1,096L, 1,135S, 1,136S, 1,137L, 1,138G, 1,139S, 1,215Y, 1,275N, 1,276N, 1,316K, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D
CDD
cd05579 (STKc_MAST_like)

1,095G

activation loop (A-loop)
1,087T, 1,088D, 1,089F, 1,095G, 1,096L, 1,135S, 1,136S, 1,137L, 1,138G, 1,139S, 1,215Y, 1,275N, 1,276N, 1,316K, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D
CDD
cd05579 (STKc_MAST_like)

1,096L

activation loop (A-loop)
1,087T, 1,088D, 1,089F, 1,095G, 1,096L, 1,135S, 1,136S, 1,137L, 1,138G, 1,139S, 1,215Y, 1,275N, 1,276N, 1,316K, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D
CDD
cd05579 (STKc_MAST_like)

1,135S

activation loop (A-loop)
1,087T, 1,088D, 1,089F, 1,095G, 1,096L, 1,135S, 1,136S, 1,137L, 1,138G, 1,139S, 1,215Y, 1,275N, 1,276N, 1,316K, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D
CDD
cd05579 (STKc_MAST_like)

1,136S

activation loop (A-loop)
1,087T, 1,088D, 1,089F, 1,095G, 1,096L, 1,135S, 1,136S, 1,137L, 1,138G, 1,139S, 1,215Y, 1,275N, 1,276N, 1,316K, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D
CDD
cd05579 (STKc_MAST_like)

1,137L

activation loop (A-loop)
1,087T, 1,088D, 1,089F, 1,095G, 1,096L, 1,135S, 1,136S, 1,137L, 1,138G, 1,139S, 1,215Y, 1,275N, 1,276N, 1,316K, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D
CDD
cd05579 (STKc_MAST_like)

1,138G

activation loop (A-loop)
1,087T, 1,088D, 1,089F, 1,095G, 1,096L, 1,135S, 1,136S, 1,137L, 1,138G, 1,139S, 1,215Y, 1,275N, 1,276N, 1,316K, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D
CDD
cd05579 (STKc_MAST_like)

1,139S

activation loop (A-loop)
1,087T, 1,088D, 1,089F, 1,095G, 1,096L, 1,135S, 1,136S, 1,137L, 1,138G, 1,139S, 1,215Y, 1,275N, 1,276N, 1,316K, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D
CDD
cd05579 (STKc_MAST_like)

1,215Y

activation loop (A-loop)
1,087T, 1,088D, 1,089F, 1,095G, 1,096L, 1,135S, 1,136S, 1,137L, 1,138G, 1,139S, 1,215Y, 1,275N, 1,276N, 1,316K, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D
CDD
cd05579 (STKc_MAST_like)

1,275N

activation loop (A-loop)
1,087T, 1,088D, 1,089F, 1,095G, 1,096L, 1,135S, 1,136S, 1,137L, 1,138G, 1,139S, 1,215Y, 1,275N, 1,276N, 1,316K, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D
CDD
cd05579 (STKc_MAST_like)

1,276N

activation loop (A-loop)
1,087T, 1,088D, 1,089F, 1,095G, 1,096L, 1,135S, 1,136S, 1,137L, 1,138G, 1,139S, 1,215Y, 1,275N, 1,276N, 1,316K, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D
CDD
cd05579 (STKc_MAST_like)

1,316K

activation loop (A-loop)
1,087T, 1,088D, 1,089F, 1,095G, 1,096L, 1,135S, 1,136S, 1,137L, 1,138G, 1,139S, 1,215Y, 1,275N, 1,276N, 1,316K, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D
CDD
cd05579 (STKc_MAST_like)

1,317F

activation loop (A-loop)
1,087T, 1,088D, 1,089F, 1,095G, 1,096L, 1,135S, 1,136S, 1,137L, 1,138G, 1,139S, 1,215Y, 1,275N, 1,276N, 1,316K, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D
CDD
cd05579 (STKc_MAST_like)

1,318V

activation loop (A-loop)
1,087T, 1,088D, 1,089F, 1,095G, 1,096L, 1,135S, 1,136S, 1,137L, 1,138G, 1,139S, 1,215Y, 1,275N, 1,276N, 1,316K, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D
CDD
cd05579 (STKc_MAST_like)

1,319G

activation loop (A-loop)
1,087T, 1,088D, 1,089F, 1,095G, 1,096L, 1,135S, 1,136S, 1,137L, 1,138G, 1,139S, 1,215Y, 1,275N, 1,276N, 1,316K, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D
CDD
cd05579 (STKc_MAST_like)

1,320T

activation loop (A-loop)
1,087T, 1,088D, 1,089F, 1,095G, 1,096L, 1,135S, 1,136S, 1,137L, 1,138G, 1,139S, 1,215Y, 1,275N, 1,276N, 1,316K, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D
CDD
cd05579 (STKc_MAST_like)

1,321P

activation loop (A-loop)
1,087T, 1,088D, 1,089F, 1,095G, 1,096L, 1,135S, 1,136S, 1,137L, 1,138G, 1,139S, 1,215Y, 1,275N, 1,276N, 1,316K, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D
CDD
cd05579 (STKc_MAST_like)

1,322D

activation loop (A-loop)
1,087T, 1,088D, 1,089F, 1,095G, 1,096L, 1,135S, 1,136S, 1,137L, 1,138G, 1,139S, 1,215Y, 1,275N, 1,276N, 1,316K, 1,317F, 1,318V, 1,319G, 1,320T, 1,321P, 1,322D
CDD
cd05579 (STKc_MAST_like)
active site cd00156

1,801D

active site
1,801D, 1,802E, 1,846E, 1,854G, 1,877T, 1,896I, 1,899K, 1,900P
CDD
cd00156 (REC)

1,802E

active site
1,801D, 1,802E, 1,846E, 1,854G, 1,877T, 1,896I, 1,899K, 1,900P
CDD
cd00156 (REC)

1,846E

active site
1,801D, 1,802E, 1,846E, 1,854G, 1,877T, 1,896I, 1,899K, 1,900P
CDD
cd00156 (REC)

1,854G

active site
1,801D, 1,802E, 1,846E, 1,854G, 1,877T, 1,896I, 1,899K, 1,900P
CDD
cd00156 (REC)

1,877T

active site
1,801D, 1,802E, 1,846E, 1,854G, 1,877T, 1,896I, 1,899K, 1,900P
CDD
cd00156 (REC)

1,896I

active site
1,801D, 1,802E, 1,846E, 1,854G, 1,877T, 1,896I, 1,899K, 1,900P
CDD
cd00156 (REC)

1,899K

active site
1,801D, 1,802E, 1,846E, 1,854G, 1,877T, 1,896I, 1,899K, 1,900P
CDD
cd00156 (REC)

1,900P

active site
1,801D, 1,802E, 1,846E, 1,854G, 1,877T, 1,896I, 1,899K, 1,900P
CDD
cd00156 (REC)
phosphorylation si...

1,846E

phosphorylation site
1,846E
CDD
cd00156 (REC)
intermolecular rec...

1,849F

intermolecular recognition site
1,849F, 1,850E, 1,852T, 1,853T, 1,854G
CDD
cd00156 (REC)

1,850E

intermolecular recognition site
1,849F, 1,850E, 1,852T, 1,853T, 1,854G
CDD
cd00156 (REC)

1,852T

intermolecular recognition site
1,849F, 1,850E, 1,852T, 1,853T, 1,854G
CDD
cd00156 (REC)

1,853T

intermolecular recognition site
1,849F, 1,850E, 1,852T, 1,853T, 1,854G
CDD
cd00156 (REC)

1,854G

intermolecular recognition site
1,849F, 1,850E, 1,852T, 1,853T, 1,854G
CDD
cd00156 (REC)
dimerization inter...

1,899K

dimerization interface
1,899K, 1,900P, 1,901P
CDD
cd00156 (REC)

1,900P

dimerization interface
1,899K, 1,900P, 1,901P
CDD
cd00156 (REC)

1,901P

dimerization interface
1,899K, 1,900P, 1,901P
CDD
cd00156 (REC)

Protein sequence

>MCA_03430_1
MEFSSRSHDSKPETSDLKLEQHHLQSSTDPKSKDKSAASSPQENESKIVLEFPQSLNASTSSQQEELEEKLNDSDLENQD
LQFATIQNTNVVMELALDGTILYLSDTWKEITGFEPSDLINKNISSIIIGNEDDCDIFLKASEAMKDDESSYRVRFLTYK
VQNYVTLISEKTNNNIDSSNNSFDNSVSNSPKVTDSVDNESKDNKSNTFLDNNISSTPKTSRSPSFDFKTPKVEFNNEIV
QYNEDDNFNTSTVDASCLSSYTPNQDDKNLNEIIEIEGQGVLIFNKISGEPSHTMWVLRPYSSPKPLSVDLPWKLTQTLG
FGVDLLVDYLEEISDSVINDKETLPTPPTALCRICEHYFPTWWFERHSELCLVGHKAQSDIETAHENLLDQRHTISQLLN
LMGQKFMVLASSTSNSSPSTSGSASEMSAALNASSSNGTPPSSFSSSSSMASINSASSSTSQKKIEYRGHQLPISAEIFA
VSSTSSPPPSPRIPNSTRARAIGKPLNKLNRQPVKLLELLIGLCDLAIQINYPEIKTYPASGDNSSSKKPKSNPTSTLGK
LQNNNDCHQEEEQEEGEEEEEAVGSNIRLHSPHSESNISSILKWTSPNVQDPGLALLCQDTEKYAKEKVDAVLRLGNTLK
YSDTVRREVEAMVFEVVEDTIAKAHQTKLDCSQEDSDQQIENTNEDENKYYDVEDDDTDLDSSSFFSENYLNTDAIPLST
SSPTISRRSNLVMNLNTEMDSKLPQDALDEGVHPKSTASEEVLITPKSILSNSGYSQVPAGERKLKTGLSLKISRRSTLD
LPLDSSLEELDLSNPIQIPQNKLHPRKSVSSLSMNSPSSYSSSYSSMHRNRITTNNSIDINTNLNSPSTPLSSPLLFPHE
HGSESQLSTTSTNQSTASASNSITGSNVLLRRQSSIIPELSRPPVSPLLSTTVPLVKPSQPSIKDYEIINPISRGAFGNV
FLARKKLTGDYYAIKVLKKADMIAKNQVMNVRAERAIMMSQSESPFVAKLYYTFQSKNYLYLVMEYLNGGDCAALIKALG
GLTEQWAQRYCAEVVVGVQDLHEKGIVHRDLKPDNLLIDKNGHLKLTDFGLSRMGLVRRHTRQSFSYPEAGNSNDMPPPS
SASAVSVPPPSMTTSSLGSGFSRLESKPLMKANTTPEPTTHRQSSSSSSTSNSTSNSVIENLLQDSNISLVPGYFNINSS
NTTGSSTASSSSLKYRPSLTRSESNNSTTGEALFIGSMLFGGGDRFPLDEDRESAASSSGSSENGSPRTTTITHNNSSIN
NPLYNQASFSRNNSTSSSSNSPKPLALFDPASSAVKFVGTPDYLAPETIKGVGQDEMSDWWSLGCILFEFLYGYPPFHAE
TPELVFQNILNHNIQWPSPEDEAECEIQISDNAKDLINKLLNPDPNSRIGAQSGAEEIKLHPFFDGINWETLWEENPSFV
PSVDDPESTDYFDPRGAETQDVPEDMIESDDDDQEDDENSGQLSKDDLAGNNENYQSTISDNSSSGRSSRADSFETGTFP
FPLRDLNRPKPYPSPIPAHIRDNRSRRLSEPTNDDFGSFAFKNLPVLDKANKEYLDKIKTESLEHRNSDTGRRTRGLSIS
AVPPKRPISPSINTAIPTGSGSRLPSPVRQLSSSSSNSVQYSTTLNSPLSSSSNFSPSSPSSSTTSQSGLNSCFSPRKSI
STKQRSSIAVPSSSPINCTPMSPKQSSYIPISADLSTSKGSVFIPNNRESSPELSTQPQRKHSIVRYAQTFDPSPSSSDN
EDSLRNTALFRVQKRRQISQRSQSRNTQIPSYRPLDVLLCDENPVVRYTSSKLLRELGCRVVAVSCTPEAIRCATGSVKF
DVIFTEYRFEKTTGADLARMIRNTNSLNTNCPIVVVTSHLKEAEASSQSKQHFSAILEKPPTSASFCKALEQCCFWRPKS
ASVTLAMSPLSTNSPGFLGNKASSSSSVLPKESSSPGSLSKNPLDNYSNEQASRPLPRQRLNSNNEDPKPTNISSENQS

GO term prediction

Biological Process

GO:0000160 phosphorelay signal transduction system
GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding

Cellular Component