Protein

MCA_03417_1

Length
190 amino acids

Gene name: FRQ1

Description: frequenting homolog; protein with calcium-binding domain

Browser: contigB:4378374-4378947-

RNA-seq: read pairs 1901, FPKM 123.0, percentile rank 82.2% (100% = highest expression)

Protein function

Annotation:FRQ1frequenting homolog; protein with calcium-binding domain
KEGG:K19932NCS1 neuronal calcium sensor 1
EGGNOG:0PH1HFG09591.1Calcium sensor
SGD closest match:S000002781FRQ1Calcium-binding protein NCS-1
CGD closest match:CAL0000194595orf19.4726Frequenin

Protein alignments

%idAln lengthE-value
MIA_03874_185.79%1904e-120MIA_03874_1
A0A060T4W9_BLAAD77.89%1903e-109ARAD1C45078p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C45078g PE=4 SV=1
Q6C5U1_YARLI75.79%1902e-107YALI0E15180p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E15180g PE=4 SV=1
A0A0J9XBT3_GEOCN76.32%1904e-104Similar to Saccharomyces cerevisiae YDR373W FRQ1 N-myristoylated calcium-binding protein that may have a role in intracellular signaling through its regulation of the phosphatidylinositol 4-kinase Pi OS=Geotrichum candidum GN=BN980_GECA08s02463g PE=4 SV=1
UniRef50_Q0971172.63%1904e-98Calcium-binding protein NCS-1 n=217 Tax=Eukaryota TaxID=2759 RepID=NCS1_SCHPO
A0A167DFX2_9ASCO71.58%1909e-98Frq1p OS=Sugiyamaella lignohabitans GN=FRQ1 PE=4 SV=1
A0A1E4TJC9_9ASCO67.37%1909e-94Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_55635 PE=4 SV=1
A0A1E3PMD7_9ASCO66.32%1901e-93EF-hand protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_24405 PE=4 SV=1
NCS1_YEAST64.21%1903e-91Calcium-binding protein NCS-1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FRQ1 PE=1 SV=2
A0A1D8PEF8_CANAL56.25%1926e-74Frequenin OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.4726 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0284

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 20 40 60 80 100 120 140 160 180 190

Detailed signature matches

  1. Domain IPR011992
    EF-hand domain pair
    1. SSF47473 (EF-hand)
  2. Domain IPR002048
    EF-hand domain
    1. PF00036 (EF-hand_1)
    2. PF13499 (EF-hand_7)
    3. cd00051 (EFh)
    4. PS50222 (EF_HAND_2)
    5. SM00054 (efh_1)
  3. SITE IPR018247
    EF-Hand 1, calcium-binding site
    1. PS00018 (EF_HAND_1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.10.23...
  2. G3DSA:1.10.23...
  3. PR00450 (RECOVERIN)

Residue annotation

  1. Ca2+ binding site ...
  2. Ca2+ binding site ...

Protein sequence

>MCA_03417_1
MGKGQSKLSKDELQELKKMTRFDRKELQQWYKGFLKDCPSGRLNQEDFQKIYKRFFPFGDPSLFSSYVFKVFDKDQNGMI
DFSEFICALSITSRGTFEEKLKWAFTLYDIDDDGYISYEEMLAIVSAIYKMVGSMVNLPEDESTPDKRVQKLFAMMDKNN
DGKISFEEFKEGSAVDPTIMSALQLYDGLV

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0005509 calcium ion binding

Cellular Component

None predicted.