Protein
MCA_03406_1
Length
660 amino acids
Browser: contigB:4354596-4356579+
RNA-seq: read pairs 1179, FPKM 22.0, percentile rank 44.0% (100% = highest expression)
Protein function
KEGG: | K00297 | metF | methylenetetrahydrofolate reductase (NADPH) [EC:1.5.1.20] |
---|---|---|---|
EGGNOG: | 0PH5R | PGUG_01501 | Methylenetetrahydrofolate reductase |
SGD closest match: | S000005944 | MET12 | Methylenetetrahydrofolate reductase 1 |
CGD closest match: | CAL0000201618 | orf19.5321 | Methylenetetrahydrofolate reductase |
Protein alignments
%id | Aln length | E-value | ||
---|---|---|---|---|
MIA_05637_1 | 58.46% | 650 | 0.0 | MIA_05637_1 |
A0A0J9X8D8_GEOCN | 57.10% | 669 | 0.0 | Methylenetetrahydrofolate reductase OS=Geotrichum candidum GN=BN980_GECA05s02023g PE=3 SV=1 |
A0A1E3PKC7_9ASCO | 54.55% | 660 | 0.0 | Methylenetetrahydrofolate reductase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46482 PE=3 SV=1 |
Q6CEM7_YARLI | 52.59% | 656 | 0.0 | Methylenetetrahydrofolate reductase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B14465g PE=3 SV=1 |
UniRef50_Q6CEM7 | 52.59% | 656 | 0.0 | Methylenetetrahydrofolate reductase n=6 Tax=Saccharomycetales TaxID=4892 RepID=Q6CEM7_YARLI |
A0A060TB28_BLAAD | 52.28% | 658 | 0.0 | Methylenetetrahydrofolate reductase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B12232g PE=3 SV=1 |
A0A167D496_9ASCO | 55.05% | 654 | 0.0 | Methylenetetrahydrofolate reductase OS=Sugiyamaella lignohabitans GN=MET12 PE=3 SV=1 |
Q5A5S8_CANAL | 49.62% | 665 | 0.0 | Methylenetetrahydrofolate reductase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.5321 PE=3 SV=1 |
MTHR1_YEAST | 47.80% | 659 | 0.0 | Methylenetetrahydrofolate reductase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MET12 PE=1 SV=2 |
A0A1E4TKA7_9ASCO | 47.71% | 654 | 0.0 | Methylenetetrahydrofolate reductase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30430 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.1882
Protein family membership
- Methylenetetrahydrofolate reductase (IPR003171)
Domains and repeats
-
Domain
1
100
200
300
400
500
600
660
Detailed signature matches
-
-
SSF51730 (FAD-linke...)
-
-
no IPR
Unintegrated signatures
-
mobidb-lite (disord...)
Residue annotation
-
FAD binding site c...
Protein sequence
>MCA_03406_1 MTSKSQKISDLINSLDGSTPFYSFEFFPPKTKQGGENLRARIERMAKLNPLFVTVTWGAGGSTASKSLELAGFIQQQGIN TCLHLTCTNMDKELIDKALEKCKSLGIRNILALRGDPPRGEEYQQPNSSDKFAHAVDLVKYIRQNHGDYFCIGVAAYPEG HVDGSDISNQNPENDLPYLVEKVQAGADFIITQLFYDTEKFLKFEEMLLNHPSKLFENIPIIPGLMPISTYQSFARASRL SHASIPQELLESVEKVNNNDDLVKAFGVKVLCKIMETVHSKSDKRIRGFHFYTLNLERSVALIIENSSILNSNIPSSSPL DSTEESAVQEETDGTSLPSGPEPGQRRRRRSSLTMHNRVLVEQQKPTKESQLSVTYKEMAEAVVKPVSSRDILAISSGEG SLGREVNWDDFPNGRFGDSRSPAYGVIDGYGPTLHVDAGKIFTFWGYPKTKADITNLIIEHLTGELGALPWSDDALNPET GLIQEELIAMNKRGMWTVASQPACEGVYSGDKIFGWGPKGGFVFQKPFVEFFISPEDWEQLKQKLDKHISSRDSKASVSS YYACNHTLKLETNLPRNSSSAVTWGVFPNKEILQSTIIEEESFLVWAEEAFALWKEWKYAYSPNSETYKLLSDIHDSYYL VTLVYHDFKNPEGLWNLILN
GO term prediction
Biological Process
GO:0006555 methionine metabolic process
GO:0055114 oxidation-reduction process
Molecular Function
GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity
Cellular Component
None predicted.