Protein

MCA_03364_1

Length
213 amino acids

Gene name: OPI3

Description: Phosphatidyl-N-methylethanolamine N-methyltransferase

Browser: contigB:4192248-4192890+

RNA-seq: read pairs 9484, FPKM 547.6, percentile rank 94.6% (100% = highest expression)

Protein function

Annotation:OPI3Phosphatidyl-N-methylethanolamine N-methyltransferase
KEGG:K00550OPI3 methylene-fatty-acyl-phospholipid synthase [EC:2.1.1.16]
EGGNOG:0PNCFOPI3methylene-fatty-acyl-phospholipid synthase
SGD closest match:S000003834OPI3Phosphatidyl-N-methylethanolamine N-methyltransferase
CGD closest match:CAL0000189933OPI3Phosphatidyl-N-methylethanolamine N-methyltransferase

Protein alignments

%idAln lengthE-value
MIA_01617_174.53%2126e-114MIA_01617_1
A0A0J9X6R3_GEOCN73.68%2095e-111Phosphatidyl-N-methylethanolamine N-methyltransferase OS=Geotrichum candidum GN=BN980_GECA04s04267g PE=3 SV=1
Q6C649_YARLI70.92%1967e-94Phosphatidyl-N-methylethanolamine N-methyltransferase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E12441g PE=3 SV=2
A0A060TBW0_BLAAD68.53%1973e-88Phosphatidyl-N-methylethanolamine N-methyltransferase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D37818g PE=3 SV=1
A0A1E4TEA3_9ASCO67.53%1943e-86Phosphatidyl-N-methylethanolamine N-methyltransferase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_99825 PE=3 SV=1
UniRef50_H0EX7365.05%2069e-81Phosphatidyl-N-methylethanolamine N-methyltransferase n=7 Tax=Fungi TaxID=4751 RepID=H0EX73_GLAL7
PLMT_YEAST59.71%2062e-81Phosphatidyl-N-methylethanolamine N-methyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=OPI3 PE=1 SV=1
A0A1D8PKM5_CANAL65.05%1863e-80Phosphatidyl-N-methylethanolamine N-methyltransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=OPI3 PE=3 SV=1
A0A1E3PGJ4_9ASCO54.73%2011e-72Phosphatidyl-N-methylethanolamine N-methyltransferase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83510 PE=3 SV=1
A0A167EX67_9ASCO79.12%912e-47Bifunctional phosphatidyl-N-methylethanolamine N-methyltransferase/phosphatidyl-N-dimethylethanolamine N-methyltransferase OS=Sugiyamaella lignohabitans GN=OPI3 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1855

Protein family membership

Domains and repeats

None predicted.

Detailed signature matches

  1. Family IPR007318
    Phospholipid methyltransferase
    1. PF04191 (PEMT)
  2. Family IPR024960
    Phosphatidyl-N-methylethanolamine/N-methyltransferase
    1. PS51599 (SAM_PEMT_PEM2)
    2. PIRSF005444 (PEMT_MPLS)
    3. MF_03216 (PLMT)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. NON_CYTOPLASM... (N...)
  3. TMhelix
  4. TRANSMEMBRANE (Tran...)

Protein sequence

>MCA_03364_1
MSEQFLEYFNDFVDHVDFSKKSLLISMASIAFNPIFWNIAARLEYSKKVLTKMAGGNSLYGCYGLAVTIFSLGILRDYLY
EQALREQPTWGLFIKNQDIVKPLAIAFFAAGNVLVLSSMYALGVTGTYLGDYFGILMDDIVTGFPFNICANPMYVGSTLS
FLGTALWFGKPAGVVITAFVYVMYWIALKFEEPFTAEIYAKRERERAAKLSKD

GO term prediction

Biological Process

GO:0006644 phospholipid metabolic process

Molecular Function

GO:0008170 N-methyltransferase activity

Cellular Component

None predicted.