Protein

MCA_03346_1

Length
457 amino acids

Browser: contigB:4112934-4114371+

RNA-seq: read pairs 522, FPKM 14.1, percentile rank 32.6% (100% = highest expression)

Protein function

KEGG:K03857PIGA phosphatidylinositol glycan, class A [EC:2.4.1.198]
EGGNOG:0PG2VFG00960.1phosphatidylinositol N-acetylglucosaminyltransferase GPI3 subunit
SGD closest match:S000006096SPT14Phosphatidylinositol N-acetylglucosaminyltransferase GPI3 subunit
CGD closest match:CAL0000182058SPT14Phosphatidylinositol N-acetylglucosaminyltransferase

Protein alignments

%idAln lengthE-value
MIA_01601_186.02%4220.0MIA_01601_1
A0A1E3PIQ4_9ASCO79.91%4330.0UDP-Glycosyltransferase/glycogen phosphorylase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_74649 PE=4 SV=1
Q6CGC4_YARLI77.39%4290.0YALI0A20482p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_A20482g PE=4 SV=1
A0A0J9XIQ7_GEOCN80.05%4310.0Similar to Saccharomyces cerevisiae YPL175W SPT14 UDP-GlcNAc-binding and catalytic subunit of the enzyme that mediates the first step in glycosylphosphatidylinositol (GPI) biosynthesis OS=Geotrichum candidum GN=BN980_GECA20s00780g PE=4 SV=1
UniRef50_G8YCF169.91%4320.0Piso0_002366 protein n=5 Tax=Fungi TaxID=4751 RepID=G8YCF1_PICSO
A0A060T0E9_BLAAD73.95%4300.0ARAD1C06930p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C06930g PE=4 SV=1
A0A1E4TFQ7_9ASCO66.74%4510.0Glycosyltransferase family 4 protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_57066 PE=4 SV=1
Q5A6R7_CANAL67.75%4310.0Phosphatidylinositol N-acetylglucosaminyltransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SPT14 PE=4 SV=1
GPI3_YEAST58.48%4480.0Phosphatidylinositol N-acetylglucosaminyltransferase GPI3 subunit OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SPT14 PE=1 SV=4
A0A167E040_9ASCO70.26%1952e-93Spt14p OS=Sugiyamaella lignohabitans GN=SPT14 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0093

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 457

Detailed signature matches

  1. Domain IPR013234
    PIGA, GPI anchor biosynthesis
    1. PF08288 (PIGA)
  2. Domain IPR001296
    Glycosyl transferase, family 1
    1. PF00534 (Glycos_tra...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. G3DSA:3.40.50...
  3. NON_CYTOPLASM... (N...)
  4. SSF53756 (UDP-Glyco...)
  5. TRANSMEMBRANE (Tran...)
  6. cd03796 (GT1_PIG-A_...)

Residue annotation

  1. putative ADP-bindi...

Protein sequence

>MCA_03346_1
MPYNIAMVSDFFYPQPGGVELHVYHLSQRLIDRGHSVIIITHAYGSRTGVRVLTNGLKVYYVPFLVLHRESTFPSVFSFF
PILRQILIREEIDIVHGHGSLSSLCHEGIVHGRAMGLKTVFTDHSLFGFADTASILGNKLLKFTLSDVSHVICVSHTCKE
NTVLRASLDPLNVSVIPNAVVSENFRPDASKASKDHISIVVISRLFQNKGIDLLIAVIPRICALHPTVTFTIAGSGPKGI
DLEQMREKHRLQERVELIGSIKHEEVRDVMVTGHIYLHASLTEAFGTVIVEAASCGLLVVTTNVGGIPEVLPSHMTVFAT
PDEDSLVASTSRAIKLIEEKKVQPSKFHEEIKGMYCWENVAERTEYVYDQIDSESLNEPLIDRLARFYHGGAWAGKLFVV
CIIVDVMLYHVLEWLWPRDSIDRAVKWPKKPISTPSSEDSISNQENIEDIFGTDVNY

GO term prediction

Biological Process

GO:0006506 GPI anchor biosynthetic process

Molecular Function

None predicted.

Cellular Component

None predicted.