Protein

MCA_03323_1

Length
487 amino acids

Gene name: RPN3

Description: 26S proteasome regulatory subunit RPN3

Browser: contigB:4020761-4022290-

RNA-seq: read pairs 6625, FPKM 167.7, percentile rank 86.1% (100% = highest expression)

Protein function

Annotation:RPN326S proteasome regulatory subunit RPN3
KEGG:K03033PSMD3 26S proteasome regulatory subunit N3
EGGNOG:0PFHZRPN326S proteasome non-ATPase regulatory subunit 3
SGD closest match:S000000823RPN326S proteasome regulatory subunit RPN3
CGD closest match:CAL0000191942RPN3Proteasome regulatory particle lid subunit

Protein alignments

%idAln lengthE-value
MIA_05647_173.33%4800.0MIA_05647_1
A0A0J9X8I8_GEOCN67.79%4750.0Similar to Saccharomyces cerevisiae YER021W RPN3 Essential, non-ATPase regulatory subunit of the 26S proteasome lid OS=Geotrichum candidum GN=BN980_GECA05s02276g PE=4 SV=1
A0A060TDD5_BLAAD59.83%4730.0ARAD1D47058p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D47058g PE=4 SV=1
Q6C023_YARLI59.25%4540.0YALI0F28413p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F28413g PE=4 SV=1
UniRef50_Q6C02359.25%4540.0YALI0F28413p n=90 Tax=Fungi TaxID=4751 RepID=Q6C023_YARLI
A0A161HKT4_9ASCO57.85%4840.0Proteasome regulatory particle lid subunit RPN3 OS=Sugiyamaella lignohabitans GN=RPN3 PE=4 SV=1
A0A1E3PRL9_9ASCO55.65%4691e-179Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_45658 PE=4 SV=1
A0A1D8PD15_CANAL52.82%4796e-153Proteasome regulatory particle lid subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=RPN3 PE=4 SV=1
A0A1E4THI4_9ASCO55.46%3668e-129Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_31900 PE=4 SV=1
RPN3_YEAST38.67%4816e-10326S proteasome regulatory subunit RPN3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RPN3 PE=1 SV=5

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0400

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 50 100 150 200 250 300 350 400 450 487

Detailed signature matches

  1. Domain IPR000717
    Proteasome component (PCI) domain
    1. SM00088 (PINT_4)
    2. PF01399 (PCI)
  2. Domain IPR011991
    Winged helix-turn-helix DNA-binding domain
    1. G3DSA:1.10.10.10
    2. SSF46785 ("Winged h...)
  3. Domain IPR013586
    26S proteasome regulatory subunit, C-terminal
    1. PF08375 (Rpn3_C)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SM00753 (PINT)
  2. mobidb-lite (disord...)

Protein sequence

>MCA_03323_1
MSKSKETTEFDALTVDDIKHNFAYIEKAVTNFDPKYMLQVLRELPTLRRQVSPSVLIKTIQQVYPTSDPSRDVLISAVVS
SAGQSALSSSDDAMDVDDDESNSTSSESVLPEIDIYIHLLVQTWLLKQKSIEQFSSFTDEVTKKLLTYNRRTLDYLASKV
WFYYSWSKELNGKLESIRPLLLGALRTATLRYDTETQASLITLLLRNYLSTHHVSQAENLVSKVNFPETASNALVARYFY
YLGKIKAIKLDYTAAHEHITAAIRKAPQTPLAGGFLQSAYKLNIVVELLMGIIPERSVFKMPLLEKALVPYFAVTRAVRI
GDIVQFGETIDKYNDALKKDGTFTLVLRLRQNVIKTGIRTISLSYSKISLKDICIKLQLDGEESTEHIIAKAIRDGVIDA
TIDHKHGYMQSNEVIDVYSTTQPQEAFHDRIKFCIALHNDSVKAMRYMMDESHNADLKNADQAREREKMLASELQVSDLE
DDDDFDM

GO term prediction

Biological Process

GO:0042176 regulation of protein catabolic process

Molecular Function

GO:0005515 protein binding
GO:0030234 enzyme regulator activity

Cellular Component

GO:0000502 proteasome complex