Protein

MCA_03303_1

Length
894 amino acids

Description: protein with UNC-45/Cro1/She4 domain and Armadillo-type fold

Browser: contigB:3973837-3976522-

RNA-seq: read pairs 1463, FPKM 20.2, percentile rank 41.7% (100% = highest expression)

Protein function

Annotation:protein with UNC-45/Cro1/She4 domain and Armadillo-type fold
KEGG:K21991UNC45 protein unc-45
EGGNOG:0PIQTPGUG_05041Actin cytoskeleton organization protein
SGD closest match:S000005561SHE4SWI5-dependent HO expression protein 4

Protein alignments

%idAln lengthE-value
MIA_03743_143.78%8520.0MIA_03743_1
A0A0J9XJQ4_GEOCN41.11%8274e-154Similar to Saccharomyces cerevisiae YOR035C SHE4 Protein containing a UCS (UNC-45/CRO1/SHE4) domain, binds to myosin motor domains to regulate myosin function OS=Geotrichum candidum GN=BN980_GECA24s00901g PE=4 SV=1
UniRef50_A0A0J9XJQ441.11%8279e-151Similar to Saccharomyces cerevisiae YOR035C SHE4 Protein containing a UCS (UNC-45/CRO1/SHE4) domain, binds to myosin motor domains to regulate myosin function n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XJQ4_GEOCN
A0A167FEV7_9ASCO39.63%6411e-94She4p OS=Sugiyamaella lignohabitans GN=SHE4 PE=4 SV=1
A0A060TJQ6_BLAAD36.93%6581e-87ARAD1D48752p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D48752g PE=4 SV=1
A0A1E3PGS3_9ASCO33.96%6423e-73Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_27013 PE=4 SV=1
Q6C521_YARLI34.24%6252e-64YALI0E21758p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E21758g PE=4 SV=1
SHE4_YEAST25.38%3315e-15SWI5-dependent HO expression protein 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SHE4 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1551

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 700 800 894

Detailed signature matches

  1. Domain IPR024660
    UNC-45/Cro1/She4, central domain
    1. PF11701 (UNC45-central)
  2. Domain IPR016024
    Armadillo-type fold
    1. SSF48371 (ARM repeat)
  3. Domain IPR011989
    Armadillo-like helical
    1. G3DSA:1.25.10.10
Unintegrated signatures no IPR
Unintegrated signatures
  1. mobidb-lite (disord...)

Protein sequence

>MCA_03303_1
MSTENTEKLTDSIEKLKLSLDDDKKKEYLRQVTQQIDLDNPKSITEIFNTIILANHEFNEQAVNKPTPDNSILFQLVSFS
EKNRKAFLKYITTAFQDGKDSHYVQLSKIYSSLKSHSDHKLSALSSIYSTLDFEIQRKLVEFSLDSIKVNSKTLPLSVSA
TLLLDLQIISRYFINITSNNPGSKFHNQLSYVIDNRSKILSLIAPFSDRRITTTWISPVVLILAKLFEIDSAGTEVAVQS
LIEDYLITGDHGSQVEIDSLIISFSLNTILFHINKDVGYSVFTSEAMVSQQAEFAQQKSGSPLTASEQVVVAALDLLSAA
CVHKDARAIIKSKFLNVVNYALEFSGKKSVSVIAASILVKTEYGGDKDAVAAAQAKQKDPNEPPKEESEEDTVDLKSLSK
IFEEEIAIPFKNEDNPDDDKFIFKKNEDSISKEVYGTALEGLAFTSLIPETKMRIAGNASILNNLVTILEKYNSEIPWVY
CTLSILDNITVYPPKLTPEQEKISKLKDYAAGKTKQQIEELNSAGGKRSGPTDTDQTVAARCKKIITTTKLISALSQYTP
KFTQTCKNLTASILRNLATDKTTRSKFVQEGGLSVLLYLVLPIDNSSTNSSMNEEEDSSPNWSNYRVDPKHLVIATSGIS
RILISINPAIAFSSKISPVVVIRPLLLQLKNSGLVGGFSGLQSSSSFSSLPLLDIFEALLALTNIASIDDSCRNTIVRLG
WSKLEALLTSDNTMVQRAAVELLCNLAPSPYCAEKFLDLSKDKRGPALSRLQLVAALTDLDDLAGRKAAAGALAMISEWG
VMAGIAMIQCDRLVERLEEMLEQETNSDVLIRGLVTLQNLISSNLSDKDPQNATNRTKFLNRMKKNLPAKLKALSSKTKD
PEVKEIVSEILGIL

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0005488 binding

Cellular Component

None predicted.