Protein

MCA_03277_1

Length
728 amino acids

Gene name: FRE7

Description: Ferric/cupric reductase transmembrane component 7

Browser: contigB:3888724-3890911-

RNA-seq: read pairs 701, FPKM 11.9, percentile rank 29.0% (100% = highest expression)

Protein function

Annotation:FRE7Ferric/cupric reductase transmembrane component 7
EGGNOG:0PQSNFerric reductase like transmembrane component
SGD closest match:S000005512FRE7Ferric/cupric reductase transmembrane component 7
CGD closest match:CAL0000191531CFL2Cfl2p

Protein alignments

%idAln lengthE-value
MIA_01615_139.09%7703e-171MIA_01615_1
A0A0J9XEK6_GEOCN37.21%6371e-119Similar to Saccharomyces cerevisiae YOL152W FRE7 Putative ferric reductase with similarity to Fre2p OS=Geotrichum candidum GN=BN980_GECA13s00879g PE=4 SV=1
UniRef50_A0A0J9XEK637.21%6372e-116Similar to Saccharomyces cerevisiae YOL152W FRE7 Putative ferric reductase with similarity to Fre2p n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XEK6_GEOCN
A0A167EX78_9ASCO32.15%7067e-100Fre1p OS=Sugiyamaella lignohabitans GN=FRE1 PE=4 SV=1
A0A060TID5_BLAAD36.74%4117e-79ARAD1D37862p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D37862g PE=4 SV=1
A0A1E3PGK8_9ASCO27.81%6765e-76Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_42856 PE=4 SV=1
Q6C644_YARLI33.05%4662e-73YALI0E12551p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E12551g PE=4 SV=2
A0A1D8PME3_CANAL29.83%2951e-20Cfl2p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CFL2 PE=4 SV=1
A0A1E4TLJ7_9ASCO27.44%2775e-20Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_14985 PE=4 SV=1
FRE7_YEAST21.57%3572e-14Ferric/cupric reductase transmembrane component 7 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FRE7 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2305
Predicted cleavage: 54

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 728

Detailed signature matches

  1. Domain IPR013130
    Ferric reductase transmembrane component-like domain
    1. PF01794 (Ferric_reduct)
  2. Domain IPR017938
    Riboflavin synthase-like beta-barrel
    1. SSF63380 (Riboflavi...)
  3. Domain IPR017927
    Ferredoxin reductase-type FAD-binding domain
    1. PS51384 (FAD_FR)
  4. Domain IPR013112
    FAD-binding 8
    1. PF08022 (FAD_binding_8)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. G3DSA:2.40.30.10
  3. G3DSA:3.40.50.80
  4. NON_CYTOPLASM... (N...)
  5. SFLDG01168 (Ferric_...)
  6. SFLDS00052 (Ferric_...)
  7. TMhelix
  8. TRANSMEMBRANE (Tran...)
  9. cd06186 (NOX_Duox_l...)
  10. mobidb-lite (disord...)

Residue annotation

  1. FAD binding pocket...
  2. FAD binding motif ...
  3. beta-alpha-beta st...
  4. NAD pyrophosphate ...
  5. NAD binding pocket...

Protein sequence

>MCA_03277_1
MTSVVAAASAGAQNFSSEQPFVPGHVAFPPGRLAEAISLLYYGRKLAMVYEGILISMVLIAASVHWYKKISSAKSSNKKS
SSASSSSALTSSSNSNNNNNSEDIIPLLQSQKHTATPYQKLPWYKKLYCQISGRLLRQSPTDPETFDSNVGTLLFIIFYY
ALSYFFCIYKTTEFPVLFAFRTGLISAINIPLLYIFGTKRSIMPWLMGWSYEQLTLFHMHIGYICCQTFVVHTIAFLYYF
RVPYLITHLWSIAGIIAGFSFLCIYITVRPFFRKYFYELFYAVHLFGLIVCLPALWFHHPVTRPFVAVAFLAVLYDRLVR
VLQDYRLVYSSVEVQPGDTVVIRIPKTKSQEDEVDDEDEYKNSFLVRLFSGRAPLSWGCGQHVFISVLGCHLFQSHPFTI
ASHCESSDTMDIIIRARSGFTRDILDQTVQQKLTKRWVLVHGPYGVPLDGLPKTSPDQNTVSEKKPSQKQQHKQTTTQES
TAVANTPTNYSSIEETHPSTLGNFFAQNANNGYKSKVILIAGGAGIAFTLPIYEKYRHAKLAKSKDQSNVLLSEESDLLK
TVSTSSVRHASSSSSSSSSSSSSTPRPSIDTNEDDSISSDPEVKMMWVVPQRNFIEWLPPKFIHDHSYLTLPLQEGVNAC
SGNYYDDNDFKLWVTAERRGRPDIKAQILSMMDSGRMEYNATGSDEKDGCWVGVCGPTPLVIQVRNAVAELRSEGHYNLR
FYAEVFGW

GO term prediction

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0016491 oxidoreductase activity

Cellular Component

None predicted.