Protein

MCA_03223_1

Length
337 amino acids

Gene name: RFC4

Description: Replication factor C subunit 4; DNA binding protein and ATPase

Browser: contigB:3708120-3709191+

RNA-seq: read pairs 534, FPKM 19.5, percentile rank 40.8% (100% = highest expression)

Protein function

Annotation:RFC4Replication factor C subunit 4; DNA binding protein and ATPase
KEGG:K10755RFC2_4 replication factor C subunit 2/4
EGGNOG:0PFZHRFC4replication factor C subunit
SGD closest match:S000005454RFC4Replication factor C subunit 4
CGD closest match:CAL0000187522RFC4Replication factor C subunit 4

Protein alignments

%idAln lengthE-value
MIA_01199_178.06%3190.0MIA_01199_1
A0A0J9X728_GEOCN77.18%3330.0Similar to Saccharomyces cerevisiae YOL094C RFC4 Subunit of heteropentameric Replication factor C (RF-C) OS=Geotrichum candidum GN=BN980_GECA04s02441g PE=4 SV=1
A0A1E3PHI1_9ASCO74.02%3310.0Putative subunit of heteropentameric replication factor C (RF-C) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_52645 PE=4 SV=1
A0A060T9W1_BLAAD72.37%3330.0ARAD1D17754p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D17754g PE=4 SV=1
Q6C2J6_YARLI73.19%3171e-179YALI0F07337p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F07337g PE=4 SV=1
UniRef50_A0A1V8V6A171.26%3416e-172Replication factor C subunit 4 n=1 Tax=Rachicladosporium sp. CCFEE 5018 TaxID=1974281 RepID=A0A1V8V6A1_9PEZI
A0A1D8PU93_CANAL68.65%3193e-167Replication factor C subunit 4 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=RFC4 PE=4 SV=1
RFC4_YEAST68.67%3166e-161Replication factor C subunit 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RFC4 PE=1 SV=1
A0A1E4TER3_9ASCO64.18%3351e-153Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_103062 PE=4 SV=1
A0A161HJS5_9ASCO74.09%2745e-152Replication factor C subunit 4 OS=Sugiyamaella lignohabitans GN=RFC4 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1125

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 337

Detailed signature matches

  1. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  2. Domain IPR003593
    AAA+ ATPase domain
    1. SM00382 (AAA_5)
  3. Domain IPR003959
    ATPase, AAA-type, core
    1. PF00004 (AAA)
  4. Domain IPR008921
    DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal
    1. SSF48019 (post-AAA+...)
  5. Domain IPR013748
    Replication factor C, C-terminal
    1. PF08542 (Rep_fac_C)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.10.8.60
  2. G3DSA:1.20.27...
  3. G3DSA:3.40.50...
  4. cd00009 (AAA)

Residue annotation

  1. Walker A motif cd0...
  2. ATP binding site c...
  3. Walker B motif cd0...
  4. arginine finger cd...

Protein sequence

>MCA_03223_1
MSKPESSKAGETPRVTKNTNELPWVEKYRPMVLDDIVGNEETIERFKAIARDGNMPHMIISGMPGIGKTTSVHCLARALL
GPELYHDAVLELNASDERGIDVVRGSIKTFSQKRVNLPPGRHKIVILDEADSMTAGAQQALRRTMEIYSSTTRFAFACNM
SNKIIEPLQSRCAILRFSKLTDAQVHHRLMDIIEAENVQYSDDGLSALVFSAEGDMRQAINNLQSTVSGFGFVNSENVFK
VVDQPHPIVVQKIVEACHKRDIDEALVHLKQLWDRGYSSVDIISTMFRVTKNLKNGISEEKKLMYIKEIGFTHMRILDGV
STYLQLCGCVAKLCKIK

GO term prediction

Biological Process

GO:0006260 DNA replication

Molecular Function

GO:0003677 DNA binding
GO:0005524 ATP binding

Cellular Component

None predicted.