Protein

MCA_03212_1

Length
439 amino acids

Gene name: SUP45

Description: Eukaryotic peptide chain release factor subunit 1

Browser: contigB:3681547-3683257-

RNA-seq: read pairs 7879, FPKM 221.3, percentile rank 89.2% (100% = highest expression)

Protein function

Annotation:SUP45Eukaryotic peptide chain release factor subunit 1
KEGG:K03265ETF1 peptide chain release factor subunit 1
EGGNOG:0PGF4SUP45Peptide chain release factor subunit 1
SGD closest match:S000000347SUP45Eukaryotic peptide chain release factor subunit 1
CGD closest match:CAL0000184893ERF1Translation termination factor eRF1

Protein alignments

%idAln lengthE-value
A0A0J9XAU7_GEOCN91.27%4240.0Similar to Saccharomyces cerevisiae YBR143C SUP45 Polypeptide release factor (ERF1) in translation termination OS=Geotrichum candidum GN=BN980_GECA06s02342g PE=4 SV=1
MIA_00850_192.80%4030.0MIA_00850_1
A0A161HG57_9ASCO85.85%4240.0Translation termination factor eRF1 OS=Sugiyamaella lignohabitans GN=SUP45 PE=4 SV=1
A0A1E3PLW4_9ASCO82.03%4230.0Polypeptide release factor OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_45898 PE=4 SV=1
Q59ZH8_CANAL82.49%4170.0Translation termination factor eRF1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ERF1 PE=4 SV=1
UniRef50_K2RTE781.71%4210.0Prephenate dehydratase n=7 Tax=leotiomyceta TaxID=716546 RepID=K2RTE7_MACPH
A0A1E4TCX5_9ASCO81.67%4200.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_141255 PE=4 SV=1
Q6C356_YARLI81.60%4240.0YALI0F02453p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F02453g PE=4 SV=1
ERF1_YEAST78.23%4180.0Eukaryotic peptide chain release factor subunit 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SUP45 PE=1 SV=2
A0A060T5P9_BLAAD77.64%4160.0ARAD1C14256p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C14256g PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0278

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 439

Detailed signature matches

  1. Family IPR004403
    Peptide chain release factor eRF1/aRF1
    1. TIGR03676
  2. Domain IPR005140
    eRF1 domain 1/Pelota-like
    1. SM01194 (eRF1_1_2)
    2. PF03463 (eRF1_1)
  3. Domain IPR024049
    Peptide Chain Release Factor eRF1/aRF1, N-terminal
    1. G3DSA:3.30.96...
    2. SSF55481 (N-termina...)
  4. Domain IPR005141
    eRF1 domain 2
    1. PF03464 (eRF1_2)
  5. Domain IPR029064
    50S ribosomal protein L30e-like
    1. SSF55315 (L30e-like)
    2. G3DSA:3.30.13...
  6. Domain IPR005142
    eRF1 domain 3
    1. PF03465 (eRF1_3)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.20.5.170
  2. G3DSA:3.30.42...
  3. SSF53137 (Translati...)

Protein sequence

>MCA_03212_1
MAPPPPENDAEKNIEIWKIKKLIKSLERARGNGTSMISLIIPPKGQISLIQKMLADEYGTASNIKSRVNRLSVLSAITST
QQKLKLYSRVPPNGLVIYCGEIITDEGKERKVNIDFEPFKPINTSLYLCDNKFHTEALSELLESDSKFGFIVMDGNGALF
GTLSGNTREVLHKFTVDLPKKHGRGGQSALRFARLREEKRHNYVRKVAEVAVQNFITNDKVNVTGLILAGSADFKTELST
SDMFDNRLQAKIIKVVDVSYGGENGFNQAIELSAETLANVKFIQEKKLITQYFDEISQDTGKFCYGVEDTLKALELGACD
IIIVYENLDIIRYTLKDPESETPVIVHASRNAPNKDHLLDKRTGAELEIISEQPLLEWLAENYKDFGATLEFVTDKSSEG
AQFVKGFGGIGALLRYKVNFEQLVEDSDDEYFDSDDDYI

GO term prediction

Biological Process

GO:0006415 translational termination

Molecular Function

GO:0003747 translation release factor activity

Cellular Component

GO:0005737 cytoplasm