Protein

MCA_03162_1

Length
900 amino acids

Gene name: KIC1A

Description: Serine/threonine protein kinase of the PAK/Ste20 family; in S. cerevisiae required for cell integrity.

Browser: contigB:3516528-3519294-

RNA-seq: read pairs 114, FPKM 1.6, percentile rank 10.7% (100% = highest expression)

Protein function

Annotation:KIC1ASerine/threonine protein kinase of the PAK/Ste20 family; in S. cerevisiae required for cell integrity.
KEGG:K08286E2.7.11.- protein-serine/threonine kinase [EC:2.7.11.-]
EGGNOG:0PF80PGUG_01022serine threonine protein kinase
SGD closest match:S000001144KIC1Serine/threonine-protein kinase KIC1
CGD closest match:CAL0000180380KIC1Putative serine/threonine protein kinase

Protein alignments

%idAln lengthE-value
MIA_06263_172.26%2926e-132MIA_06263_1
A0A0J9XKK1_GEOCN64.19%2965e-126Similar to Saccharomyces cerevisiae YHL007C STE20 Cdc42p-activated signal transducing kinase of the PAK (P21-activated kinase) family OS=Geotrichum candidum GN=BN980_GECA23s01066g PE=4 SV=1
UniRef50_A0A0J9XKK164.19%2961e-122Similar to Saccharomyces cerevisiae YHL007C STE20 Cdc42p-activated signal transducing kinase of the PAK (P21-activated kinase) family n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XKK1_GEOCN
A0A167E2N9_9ASCO63.70%2926e-119Putative serine/threonine protein kinase KIC1 OS=Sugiyamaella lignohabitans GN=KIC1 PE=4 SV=1
A0A060TA49_BLAAD63.10%2906e-119ARAD1B04752p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B04752g PE=4 SV=1
Q6C3K8_YARLI63.01%2921e-114YALI0E34001p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E34001g PE=4 SV=1
Q59LK7_CANAL60.69%2906e-112Putative serine/threonine protein kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=KIC1 PE=4 SV=1
A0A1E3PER9_9ASCO67.32%2574e-112Kinase-like protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_27474 PE=3 SV=1
KIC1_YEAST57.60%2833e-101Serine/threonine-protein kinase KIC1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=KIC1 PE=1 SV=1
A0A1E4TL05_9ASCO59.04%2713e-108Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_20474 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0706

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 800 900 900

Detailed signature matches

  1. Domain IPR011009
    Protein kinase-like domain
    1. SSF56112 (Protein k...)
  2. Domain IPR000719
    Protein kinase domain
    1. PS50011 (PROTEIN_KI...)
    2. SM00220 (serkin_6)
    3. PF00069 (Pkinase)
  3. SITE IPR017441
    Protein kinase, ATP binding site
    1. PS00107 (PROTEIN_KI...)
  4. SITE IPR008271
    Serine/threonine-protein kinase, active site
    1. PS00108 (PROTEIN_KI...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:1.10.51...
  3. G3DSA:3.30.20...
  4. mobidb-lite (disord...)

Protein sequence

>MCA_03162_1
MSLQKRYDHPTDYVKEEIIGRGSFGVVYKGKNKHTKEAVAIKILNLDKVEDDVQDVQQEINLLSKLSKSSSLNIVAYHCC
FLVDTKLWIIMELCSGGSVRTLLKAGKLEEKYCAVIIREMLIALQYIHKEGIIHRDIKAANVLINTDGHVKLCDFGVAAQ
LSSSQYKRTSMIGTPYWMAPEVIKEGSGYNQKADIWSLGITLYEMITGAPPFSDQKPERALNLISRAKPTRLEGNQYSPA
LKEFVAMCLDEQPDERLSADELLKSKLVKNYKSYPYTILKEVITRYQLWRESHRNVRDSFLIPNPNAAGGTFTSLDGDDD
DEDSGDSSSFDWDFDTTTDLPNDQNMASSTPFGATTLRTNTNFTDTNTDILSPHEPTYRPTDMGGYFASHSISGSTAVPG
ASTSQTDSSYTSYSSTTERHPLLEMFDEVPPADSNNNMVPPGNINMGLPGSLSMQNTMSTFNTPIDISANSPFGNPIALH
QQSGSSYFPGGNIQSPMLLKQQSASSASTPNLMNVASASSNMAFAKRIPSSTQNLQNGLITPKPLKQVIVPPNLSNSMPK
NTPPSQSTDYQHNSANFNSMRPPSPVRSSNSGSLGSSTELNKADGKAINKNLVSNSLATSFSTTSLPSINTNVSGETGSN
QKTSTNGSDRSGINMKESSHIKHIAQRKVSAPSSLRTVIPNADPTQDSTKTSLNTPGSTPSSTPLMKSYQTSQLPSSSSN
QYKGYSQNTNKGNSKTNNIQQYNQQLEMLQRQQMDSIVSNNAKKDFSTSSQSTTSGVSPPIASASASLPLTSSSKHGSSK
LNIAQHAEEISNNLLGKTQKLSLKQRQLSASGPYSGFQHQHGSSTRSNGVPFPPLKMVDCNILLDNVSKDVVIKEFGYQL
NSFLQALNAIEDEMKGYVIN

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0005524 ATP binding

Cellular Component

None predicted.