Protein

MCA_03159_1

Length
468 amino acids

Gene name: MRM1

Description: rRNA methyltransferase 1, mitochondrial

Browser: contigB:3512968-3514375-

RNA-seq: read pairs 888, FPKM 23.4, percentile rank 45.7% (100% = highest expression)

Protein function

Annotation:MRM1rRNA methyltransferase 1, mitochondrial
KEGG:K15507MRM1 21S rRNA (GM2251-2'-O)-methyltransferase [EC:2.1.1.-]
EGGNOG:0PP14PGUG_01024RNA methyltransferase
SGD closest match:S000005727MRM1rRNA methyltransferase 1, mitochondrial
CGD closest match:CAL0000190347orf19.182Uncharacterized protein

Protein alignments

%idAln lengthE-value
MIA_06261_143.01%4793e-114MIA_06261_1
UniRef50_W1QKE232.67%4531e-55rRNA methylase, putative, group 3 n=2 Tax=Ogataea TaxID=461281 RepID=W1QKE2_OGAPD
A0A060T5L7_BLAAD31.85%4497e-55ARAD1B05280p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B05280g PE=4 SV=1
A0A0J9XJS2_GEOCN47.78%2033e-50Similar to Saccharomyces cerevisiae YOR201C MRM1 Ribose methyltransferase that modifies a functionally critical, conserved nucleotide in mitochondrial 21S rRNA OS=Geotrichum candidum GN=BN980_GECA23s01088g PE=4 SV=1
A0A1E3PEQ8_9ASCO30.90%3982e-45RNA methyltransferase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83984 PE=4 SV=1
A0A167E2M7_9ASCO33.95%3773e-44Mrm1p OS=Sugiyamaella lignohabitans GN=MRM1 PE=4 SV=1
MRM1_YEAST28.94%4631e-43rRNA methyltransferase 1, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MRM1 PE=1 SV=2
A0A1D8PHA0_CANAL31.43%2103e-27Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.182 PE=4 SV=1
Q6C040_YARLI33.00%2004e-23YALI0F27995p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F27995g PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.4821
Predicted cleavage: 41

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 468

Detailed signature matches

  1. Domain IPR029064
    50S ribosomal protein L30e-like
    1. SSF55315 (L30e-like)
    2. G3DSA:3.30.13...
  2. Domain IPR013123
    RNA 2-O ribose methyltransferase, substrate binding
    1. PF08032 (SpoU_sub_bind)
    2. SM00967 (SpoU_sub_b...)
  3. Domain IPR029028
    Alpha/beta knot methyltransferases
    1. SSF75217 (alpha/bet...)
  4. Domain IPR029026
    tRNA (guanine-N1-)-methyltransferase, N-terminal
    1. G3DSA:3.40.12...
  5. Domain IPR001537
    tRNA/rRNA methyltransferase, SpoU type
    1. PF00588 (SpoU_methy...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. mobidb-lite (disord...)

Protein sequence

>MCA_03159_1
MKFTQFLMQVRPALKKKYLPQNTQGVSNFDRNFPSAKAQKAWGDKNKDEFFRKKYAHVHAYQKKRNELKSPKKEEDSKPE
RPSRSREAKRTKVIPFHDFIHGRTSVLAALYSTKRSGISMLYTSKEESDMDKEMLKMAELRNIPIQFVTQQKLDQITSKQ
TNNGYALRTRPLEPPNVDYLVFNNLEKAPGLVSDSDNAPPAPKPFSFQYDEESNTNITNPEPDLDSTASQESTNGTPFDF
GIVEHIEGGVSIETVLKTPKRIHSHAVGLYIDEVTDPHNMGAILRSAQFLGIDFGVVSSLNSSKLSPTVSKVSAGALELF
DLYSCESPLKFFEKSRLEGWNIIAAVPSTLKTSNIIPPKKSLEQSPVGSKHELQRVQLNQLKDLSLQGPCLLVVGSEGQG
LRKSLLQRCTHIVSIENKAAGYAAEEPDVDNGNKNLANLIDSPKKMAQLLDSLNVSVATAILLSKLTE

GO term prediction

Biological Process

GO:0006396 RNA processing

Molecular Function

GO:0003723 RNA binding
GO:0008168 methyltransferase activity
GO:0008173 RNA methyltransferase activity

Cellular Component

None predicted.