Protein

MCA_03156_1

Length
429 amino acids

Gene name: RIO2

Description: Serine/threonine protein kinase Rio2; in S. cerevisiae involved in the processing of 20S pre-rRNA

Browser: contigB:3508584-3509874-

RNA-seq: read pairs 2414, FPKM 69.4, percentile rank 72.4% (100% = highest expression)

Protein function

Annotation:RIO2Serine/threonine protein kinase Rio2; in S. cerevisiae involved in the processing of 20S pre-rRNA
KEGG:K07179RIOK2 RIO kinase 2 [EC:2.7.11.1]
EGGNOG:0PFZSPGUG_01955serine threonine-protein kinase RIO2
SGD closest match:S000005151RIO2Serine/threonine-protein kinase RIO2
CGD closest match:CAL0000193362RIO2Protein kinase

Protein alignments

%idAln lengthE-value
MIA_04383_164.29%4065e-179MIA_04383_1
A0A0J9XDP6_GEOCN67.45%3414e-160Similar to Saccharomyces cerevisiae YNL207W RIO2 Essential serine kinase involved in the processing of the 20S pre-rRNA into mature 18S rRNA OS=Geotrichum candidum GN=BN980_GECA11s00417g PE=4 SV=1
A0A060T3P2_BLAAD62.91%3376e-154ARAD1C35332p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C35332g PE=4 SV=1
Q6BZR9_YARLI64.48%3351e-152YALI0F31383p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F31383g PE=4 SV=1
UniRef50_Q6BZR964.48%3352e-149YALI0F31383p n=90 Tax=Fungi TaxID=4751 RepID=Q6BZR9_YARLI
A0A167FFW7_9ASCO64.00%3252e-148Protein kinase RIO2 OS=Sugiyamaella lignohabitans GN=RIO2 PE=4 SV=1
A0A1E4TDY9_9ASCO60.48%3343e-144Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_98252 PE=4 SV=1
A0A1E3PJL9_9ASCO58.77%3252e-139Uncharacterized protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46295 PE=4 SV=1
Q5A396_CANAL56.42%3352e-129Protein kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=RIO2 PE=4 SV=1
RIO2_YEAST47.48%4573e-129Serine/threonine-protein kinase RIO2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RIO2 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0728

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 400 429

Detailed signature matches

  1. Domain IPR011991
    Winged helix-turn-helix DNA-binding domain
    1. G3DSA:1.10.10.10
    2. SSF46785 ("Winged h...)
  2. Domain IPR015285
    RIO2 kinase winged helix domain, N-terminal
    1. PF09202 (Rio2_N)
  3. Domain IPR011009
    Protein kinase-like domain
    1. SSF56112 (Protein k...)
  4. Domain IPR000687
    RIO kinase
    1. SM00090 (rio_2)
  5. Domain IPR030484
    Serine/threonine-protein kinase Rio2
    1. cd05144 (RIO2_C)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:1.10.51...
  3. G3DSA:3.30.20...
  4. PF01163 (RIO1)
  5. mobidb-lite (disord...)

Residue annotation

  1. ATP binding site c...

Protein sequence

>MCA_03156_1
MKFDLNHMRYLTNEDFRVLTAIEMGSRNHELVPTKMISQIAGLRSGSRCEYSISQLCKARLVRKIRNAKYDGYKLSHLGY
DYLALKSFLKRDTIFSVGNQIGIGKESDIFVVANEQGDNFVLKVHRLGRTSFKTVKTNRDYLKNRHSTSWMYMSRLAAQK
EFEFMKALYDAGFQVPVPIDQSRHMVVMSLVKGFPMRQLTEHGEAGRLYLTLMNFIIKLANQGLIHCDFNEFNIMIRDDY
DPEKDDPEKEVTIIDFPQCVSINHSEAKRFFERDVNSIRSFFDKKLGYIPLDGWYPVWERDVKREGTLDALVEASGITKK
DIKEFEKVLAESREAFGIEKEGGELKDSDDEFDEDEMFEIEEDYTERGESAKSEKRNDDDDDDSEEEESSEDEEEEEDEE
DDYEKRLAKAIAEVGLENIKQDKLGNYIV

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding

Cellular Component

None predicted.