Protein

MCA_03149_1

Length
1,604 amino acids

Description: Putative ATP-dependent RNA helicase

Browser: contigB:3494509-3499386-

RNA-seq: read pairs 780, FPKM 6.0, percentile rank 19.1% (100% = highest expression)

Protein function

Annotation:Putative ATP-dependent RNA helicase
EGGNOG:0PI46FG07142.1DEAD DEAH box helicase
SGD closest match:S000004411YLR419WPutative ATP-dependent RNA helicase YLR419W
CGD closest match:CAL0000175865orf19.6818Putative helicase

Protein alignments

%idAln lengthE-value
MIA_00868_156.90%16170.0MIA_00868_1
A0A0J9X6M7_GEOCN48.01%15600.0Similar to Saccharomyces cerevisiae YLR419W Putative helicase with limited sequence similarity to human Rb protein OS=Geotrichum candidum GN=BN980_GECA04s00659g PE=4 SV=1
UniRef50_A0A0J9X6M748.01%15600.0Similar to Saccharomyces cerevisiae YLR419W Putative helicase with limited sequence similarity to human Rb protein n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X6M7_GEOCN
A0A167D5R3_9ASCO44.36%14540.0Putative helicase OS=Sugiyamaella lignohabitans GN=AWJ20_772 PE=4 SV=1
A0A060TBK9_BLAAD41.57%15950.0ARAD1B08822p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B08822g PE=4 SV=1
Q6CDA6_YARLI35.93%15640.0YALI0C02365p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C02365g PE=4 SV=1
A0A1E3PHE5_9ASCO37.24%16110.0p-loop containing nucleoside triphosphate hydrolase protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_43129 PE=4 SV=1
A0A1E4TG79_9ASCO33.70%15610.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_110676 PE=4 SV=1
Q5ADM3_CANAL32.26%16120.0Putative helicase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.6818 PE=4 SV=1
YL419_YEAST32.66%15770.0Putative ATP-dependent RNA helicase YLR419W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YLR419W PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1139
Predicted cleavage: 52

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 200 400 600 800 1000 1200 1400 1604

Detailed signature matches

  1. Domain IPR009060
    UBA-like
    1. SSF46934 (UBA-like)
  2. Domain IPR015940
    Ubiquitin-associated domain
    1. PS50030 (UBA)
  3. Domain IPR016135
    Ubiquitin-conjugating enzyme/RWD-like
    1. SSF54495 (UBC-like)
    2. G3DSA:3.10.11...
  4. Domain IPR006575
    RWD domain
    1. PS50908 (RWD)
    2. PF05773 (RWD)
  5. Domain IPR014001
    Helicase superfamily 1/2, ATP-binding domain
    1. PS51192 (HELICASE_A...)
    2. SM00487 (ultradead3)
  6. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  7. Domain IPR011545
    DEAD/DEAH box helicase domain
    1. PF00270 (DEAD)
  8. Domain IPR001650
    Helicase, C-terminal
    1. PS51194 (HELICASE_CTER)
    2. SM00490 (helicmild6)
    3. PF00271 (Helicase_C)
  9. Domain IPR007502
    Helicase-associated domain
    1. SM00847 (ha2_5)
    2. PF04408 (HA2)
  10. SITE IPR002464
    DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site
    1. PS00690 (DEAH_ATP_H...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. G3DSA:1.10.8.10
  3. G3DSA:3.30.16...
  4. G3DSA:3.40.50...
  5. NON_CYTOPLASM... (N...)
  6. TRANSMEMBRANE (Tran...)
  7. cd00046 (DEXDc)
  8. cd00079 (HELICc)
  9. mobidb-lite (disord...)

Residue annotation

  1. ATP binding site c...
  2. putative Mg++ bind...
  3. nucleotide binding...
  4. ATP-binding site c...

Protein sequence

>MCA_03149_1
MKQKNSNSSKPSNGGNGSKGKQSNDNQNAGSAGPNKSARGKRPPMNPEARKTVTKSSSWTGKLPATLLYEYCQKQKWEKV
QFDMRSNDKGFTATAVLSWRNPKTGQTEVIRMSPPPDVLSPQKTALEARHVTATYALHRVASHRNMKPMLPPDHRTIWSK
LDDLKKQHLAAASSLDKDKNNKKPDPKAKSTNNATDKIHIGKFFEDKSYLYAEDPFLVERERKATKEKIMSMQNSEEHKK
KMEMRKVMNSVQSVLSTEKNMSSLSLEDKQQSKDSSRSPTPNSNYDTAAQEQPRKRRPAFKKWLFMSKESRLMAESLIKK
YHGFSYQTRDVKSEHWTEVSKSIKTALLSMGFPQNQADEALEYTSSLSDALEWLLIHVPEDDLPDMFASTPETKDSRLTA
TIMSSDLKFEYAIRDIRAQTGFSEDLIREYLKAVKGNKRLAIVALTHILSSKSSDDNDDESEIKEIPFEDNEQSIEYWNE
EMESLEAIYNEDEFISFKEEGYCTFIFEITTKTKGNSKPISSKKQQSNKTTFKIKMSLWKSFDYPHSIPGIMLDISKHSS
DSGDKGTILARYHMLDLIKRTGRYANEALLDEFMVLSIVEWFKDNFEDVLNNPSRLTDLSSGVSGQKKTTSLSPESSSLS
LSKAKITSSKSNTNSRAQKRENKFDAKQLQQLYSEKLQNSPKLKDMIKFRETLPAWQKREEILKLIASNQVVLVTGETGS
GKSTQVAQFILDAAIKSNTKGPLNIICSQPRRISAMGLAQRVSDERDEPVGTQVGYIIRGESKTSKSTLLSFVTTGVLLR
MIQQQQQSNSPSFLDSISHIMVDEVHERSLDSDFLLILLKRIISQRKDLKVILMSATVDKSLFINYFGGDSKVGYTHIEG
RTFPVQDYYLDDAVNFTNYVPPIMPKSTFKIKLSDQDDNNFDDDNDNDNDDYEEGSNIKKYYSQGSKEDIMERKLYAISQ
LGIAYDLISQLVSYIDSKLGSADGSILIFMPGTAEIDRCISTIQSSSKGFMYHTLPLHASLAPAEQRKVFNNPPKGKRKI
VVSTNVAETSITIPDIVAVIDTGRVKETKYDPTSNVTRLVNGWTSKAAATQRRGRAGRVREGLCFKLFTKSTEKKQMPTR
QLPELLRVPLEQLYLSVKAMGIKSTMRFLSEALDPPHVSAIDRARYTLKQLGALEHNVSNGLNDDSNEALTPLGMHMSMI
PTDLRCAKLLVLSAMFGCINTGLIIASIMSLKSPFVAPSAKREEMKKHMIQNFAESGCSIKEGGVGDLLIQAKAYYEWEK
RQPQKQGVSSFEKKNHSMSTSQLRKWCRDNFLSYQTLQDIQSTKLQFISSLQEIGYLPSGSHQDIPEKYTVNDDLETLKK
TGLVRAVIGASMGSTNVGNVVLPEKVFKNVGGVGAVEVANTDAKAIKIFGPNVQDDLQQQQASTGGTNKASGGNGDASQN
ANRIVERLFIHPGSSLFETTKFLDDTLHNPDRSLVGYGDGGFLTFARKVHTSRLFIDGLTPLNTYGLVFFSDNLKVDTLG
NGVVISTGMPATSDTNSLKLQADSGDWLGLKCWPRIGILVKLLRHLFNNLITQKFDNPELDLSENEVISFIQNLIETNGA
VNQG

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003676 nucleic acid binding
GO:0004386 helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding

Cellular Component

None predicted.