Protein

MCA_03121_1

Length
526 amino acids

Gene name: TRM13

Description: tRNA:m(4)X modification enzyme TRM13

Browser: contigB:3429152-3430810+

RNA-seq: read pairs 306, FPKM 7.2, percentile rank 20.9% (100% = highest expression)

Protein function

Annotation:TRM13tRNA:m(4)X modification enzyme TRM13
KEGG:K15446TRM13 tRNA:m4X modification enzyme [EC:2.1.1.225]
EGGNOG:0PIFCTRM13tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His)
SGD closest match:S000005485TRM13tRNA:m(4)X modification enzyme TRM13
CGD closest match:CAL0000175614CAALFM_CR00670CAtRNA:m4X modification enzyme

Protein alignments

%idAln lengthE-value
MIA_01334_144.44%5045e-124MIA_01334_1
A0A0J9X304_GEOCN38.89%5407e-105Similar to Saccharomyces cerevisiae YOL125W TRM13 2'-O-methyltransferase responsible for modification of tRNA at position 4 OS=Geotrichum candidum GN=BN980_GECA01s07578g PE=4 SV=1
UniRef50_A0A0J9X30438.89%5401e-101Similar to Saccharomyces cerevisiae YOL125W TRM13 2'-O-methyltransferase responsible for modification of tRNA at position 4 n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X304_GEOCN
A0A1E3PF45_9ASCO39.37%5084e-89DUF715-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_52917 PE=4 SV=1
A0A060T5S3_BLAAD39.68%4993e-85ARAD1C14762p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C14762g PE=4 SV=1
A0A167D9G4_9ASCO33.96%5337e-74Trm13p OS=Sugiyamaella lignohabitans GN=TRM13 PE=4 SV=1
TRM13_YARLI32.18%5471e-67tRNA:m(4)X modification enzyme TRM13 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=TRM13 PE=3 SV=1
TRM13_YEAST33.53%5163e-62tRNA:m(4)X modification enzyme TRM13 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TRM13 PE=1 SV=1
A0A1D8PRS2_CANAL30.65%4968e-52tRNA:m4X modification enzyme OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CAALFM_CR00670CA PE=4 SV=1
A0A1E4TED3_9ASCO30.29%4824e-41Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_12903 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0086

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 450 500 526

Detailed signature matches

  1. Domain IPR021721
    Zinc finger, CCCH-type, TRM13
    1. PF11722 (zf-TRM13_CCCH)
  2. Domain IPR022776
    TRM13/UPF0224 family, U11-48K-like CHHC zinc finger domain
    1. PF05253 (zf-U11-48K)
    2. PS51800 (ZF_CHHC_U1...)
  3. Domain IPR007871
    Methyltransferase TRM13
    1. PF05206 (TRM13)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. mobidb-lite (disord...)

Protein sequence

>MCA_03121_1
MSTSSPVTKKQKIDHNSNDAKQKTPESIIEANKPERLQCHFVLVHKGGRRCKMTRPSWSNFCSQHQDVNTTSSSGSLVSE
PSNDNNNNKNNTDNNKRVPCPLDPNHTVRESQLQRHIKKCPKAKAPPKDVWFNLDMNIVNKGAFNSVNNDNDKTFKTSPE
YYQHMEKVLEKVWETVLNKQDPELQVLSHPGLDSRLSELEKPKHAIQQSSLIGHMKNLGLLDVINNDSNNSSKSGKNPIT
IEFGCGRAELSRYVSRAHFFSCSEDDDNPTTISTNDNNNTDQSSTDITRPFLLVDRAGPRMKFDSKLEKDYNEEQEEKGK
KRIGKPVVKRVLIDIKDLDLYTALETQFGNHQEKKQEEKEERQIVAISKHLCGCATDLTLECLRNCCQVKSQENDSNNKY
SLKGLVIALCCRHICSFETYPAIDFLFENGLISKEFPQESFKAFVRMTSWVVNGRRENMKDETEENAFINSTGLSIKQRE
KMGLIARRCIDYGRVLALKRYYSSVKLVQYVQSDVSLENVALLVKL

GO term prediction

Biological Process

GO:0008033 tRNA processing

Molecular Function

GO:0008168 methyltransferase activity

Cellular Component

None predicted.