Protein
MCA_03067_1
Length
713 amino acids
Gene name: RAD24
Description: Checkpoint protein Rad24; in S. cerevisiae involved in the activation of the DNA damage and meiotic pachytene checkpoints; subunit of a clamp loader that loads Rad17p-Mec3p-Ddc1p onto DNA.
Browser: contigB:3238990-3241132+
RNA-seq: read pairs 955, FPKM 16.5, percentile rank 36.3% (100% = highest expression)
Protein function
| Annotation: | RAD24 | Checkpoint protein Rad24; in S. cerevisiae involved in the activation of the DNA damage and meiotic pachytene checkpoints; subunit of a clamp loader that loads Rad17p-Mec3p-Ddc1p onto DNA. | |
|---|---|---|---|
| KEGG: | K06662 | HRAD17 | cell cycle checkpoint protein |
| EGGNOG: | 0PFQ2 | RAD17 | cell cycle checkpoint protein RAD17 |
| SGD closest match: | S000000975 | RAD24 | Checkpoint protein RAD24 |
| CGD closest match: | CAL0000199943 | orf19.2728 | Uncharacterized protein |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_02710_1 | 33.69% | 567 | 5e-75 | MIA_02710_1 |
| A0A0J9X751_GEOCN | 31.78% | 538 | 1e-68 | Similar to Saccharomyces cerevisiae YER173W RAD24 Checkpoint protein, involved in the activation of the DNA damage and meiotic pachytene checkpoints OS=Geotrichum candidum GN=BN980_GECA04s06852g PE=4 SV=1 |
| UniRef50_A0A0J9X751 | 31.78% | 538 | 2e-65 | Similar to Saccharomyces cerevisiae YER173W RAD24 Checkpoint protein, involved in the activation of the DNA damage and meiotic pachytene checkpoints n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X751_GEOCN |
| A0A060T443_BLAAD | 29.55% | 379 | 2e-35 | ARAD1C41162p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C41162g PE=4 SV=1 |
| A0A167DMB9_9ASCO | 29.87% | 395 | 1e-30 | Rad24p OS=Sugiyamaella lignohabitans GN=RAD24 PE=4 SV=1 |
| A0A1E3PJR4_9ASCO | 27.29% | 425 | 4e-27 | Rad17-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_50874 PE=4 SV=1 |
| RAD24_YEAST | 31.34% | 335 | 1e-23 | Checkpoint protein RAD24 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RAD24 PE=1 SV=1 |
| Q6CES5_YARLI | 26.43% | 401 | 3e-21 | YALI0B13376p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B13376g PE=4 SV=1 |
| A0A1E4TH96_9ASCO | 28.64% | 391 | 2e-19 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_2837 PE=4 SV=1 |
| Q5AF80_CANAL | 24.18% | 335 | 2e-18 | Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.2728 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.5273
Predicted cleavage: 13
Protein family membership
None predicted.
Domains and repeats
-
Domain
1
100
200
300
400
500
600
713
Detailed signature matches
-
-
SSF52540 (P-loop co...)
-
no IPR
Unintegrated signatures
-
-
-
-
PF03215 (Rad17)
-
mobidb-lite (disord...)
Protein sequence
>MCA_03067_1 MNFNVIPSSSRNDGLVKKHNTQRAQHKANRSDLPLQNRFIDTFKDGFAGFNSDSSDDDSSKSSDSSSSEDEEDNGPKLVT AGNLLDNMFTTSRNSVQSEIQRPLSPPLKKQRLTTSASSSSPTPNSSLFNGDATVEERQSLSWVEKYAPTSVEQVALHSM KKKEVVETLMQIASGKSPIRLLILSGPAGTSKSTIVKTAFKEVYQRIQRAKQTLPNNSSQYPIRQQAQPEISKEPKFVEW VTPELTMGKSLPMEFRNFLVGSKFQGNYSDCLVLIEDLPNVSHHATREVFNRSLLEWLDNSSSKSKYPCIVIIVTEVEVS SGNEGYSSGFMTGYTNPASVITERIFDSSILALNKTVKRIKFNKVAKSICAKSLKYIAEQEAKEQIQIIQSNRKNKRPIT KSVWQKIPPGLLKNIIDTLSQYGDIRSSINTFEYLIKSSSTSANVASSIKFGLDLMKRDNQVDLFHTAGKVLYVSMKDRS GVEISDEDQVVQAIVDDWGVSSRGDQQSLEGVLFENYIFQTTNLSTITRSMEVLELGNVISSLSNSKSFGANSINFSENS AGGMVVTEVASQLEVRGLRLAMKNKPPNSSRSSRSSAMRFPKFMKKKEAQTVELEQELKRLKFESLVDRRNPTDIESLTT FEKYYMEIIPTLHETKRIDNKDDNNTVMAAKNNTEQVSIIEAPLKETKEESKMSLDDMLDDDDFFESIELSLL
GO term prediction
Biological Process
None predicted.
Molecular Function
None predicted.
Cellular Component
None predicted.