Protein

MCA_03063_1

Length
455 amino acids

Gene name: RPD3

Description: Histone deacetylase RPD3

Browser: contigB:3232208-3233861+

RNA-seq: read pairs 2899, FPKM 78.6, percentile rank 74.9% (100% = highest expression)

Protein function

Annotation:RPD3Histone deacetylase RPD3
KEGG:K06067HDAC1_2 histone deacetylase 1/2 [EC:3.5.1.98]
EGGNOG:0PHUXRPD3histone deacetylase
SGD closest match:S000005274RPD3Histone deacetylase RPD3
CGD closest match:CAL0000185568RPD31Histone deacetylase

Protein alignments

%idAln lengthE-value
MIA_03023_192.26%4520.0MIA_03023_1
A0A0J9X7I6_GEOCN90.02%4510.0Histone deacetylase OS=Geotrichum candidum GN=BN980_GECA03s07281g PE=3 SV=1
Q6C4X6_YARLI83.81%4510.0Histone deacetylase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E22935g PE=3 SV=1
A0A060T7D6_BLAAD82.21%4440.0Histone deacetylase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C27500g PE=3 SV=1
UniRef50_Q6BMV178.73%4420.0Histone deacetylase n=23 Tax=Dikarya TaxID=451864 RepID=Q6BMV1_DEBHA
Q5ADP0_CANAL76.30%4430.0Histone deacetylase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=RPD31 PE=1 SV=1
A0A1E3PE45_9ASCO78.00%4410.0Histone deacetylase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_53224 PE=3 SV=1
RPD3_YEAST79.21%4330.0Histone deacetylase RPD3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RPD3 PE=1 SV=1
A0A167EGF8_9ASCO82.09%4300.0Histone deacetylase OS=Sugiyamaella lignohabitans GN=RPD3 PE=3 SV=1
A0A1E4T9Z7_9ASCO74.16%4490.0Histone deacetylase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_33060 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0092

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 455

Detailed signature matches

  1. Family IPR000286
    Histone deacetylase superfamily
    1. PR01270 (HDASUPER)
  2. Family IPR003084
    Histone deacetylase
    1. PR01271 (HISDACETLASE)
    2. PIRSF037913 (HDAC_I...)
  3. Domain IPR023801
    Histone deacetylase domain
    1. G3DSA:3.40.80...
    2. PF00850 (Hist_deacetyl)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF52768 (Arginase/...)
  2. mobidb-lite (disord...)

Protein sequence

>MCA_03063_1
MVLEAAPLDPVTIKPNEKRRVAYFYDSDVGNYAYGTGHPMKPHRIRMAHSLIMNYGLYKHMEIYRAKPATKQEMCQFHTD
EYIDFLSRVTPENADMFSKEQVKFNVGDDCPVFDGLFEFCGISGGGSMEGAARLNREKCDIAINWAGGLHHAKKSEASGF
CYLNDIVLGIIELLRYHARVLYIDIDVHHGDGVEEAFYSTDRVMTCSFHKYGEFFPGTGELRDIGVGKGKYYAVNFPFRD
GIDDTNYKSIFEPVITAIMEWYQPSAVVLQCGGDSLSGDRLGCFNLSMYGHSNCVKFVKSFGLPTLVVGGGGYTMRNVSR
AWTYETGILNNKIVGPEIPYNDYYEYYGPDYRLEVRPSNMQNANSREYLNKILTQVLQNLSRTKFAPSVQMQDVPRDAED
LGDEEEDEEESKETRGGSLQRRDEEVEATGEFFDDEDKSGGKKQEINYKDAVPAI

GO term prediction

Biological Process

GO:0016575 histone deacetylation

Molecular Function

GO:0004407 histone deacetylase activity

Cellular Component

None predicted.