Protein

MCA_03040_1

Length
247 amino acids

Gene name: YUH1

Description: Ubiquitin carboxyl-terminal hydrolase YUH1

Browser: contigB:3170473-3171217+

RNA-seq: read pairs 1149, FPKM 57.2, percentile rank 68.3% (100% = highest expression)

Protein function

Annotation:YUH1Ubiquitin carboxyl-terminal hydrolase YUH1
KEGG:K05609UCHL3 ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
EGGNOG:0PFJZYUH1ubiquitin carboxyl-terminal hydrolase
SGD closest match:S000003860YUH1Ubiquitin carboxyl-terminal hydrolase YUH1
CGD closest match:CAL0000198739orf19.6272Ubiquitin carboxyl-terminal hydrolase

Protein alignments

%idAln lengthE-value
MIA_04769_154.51%2444e-94MIA_04769_1
A0A161HME6_9ASCO54.73%2434e-91Ubiquitin carboxyl-terminal hydrolase OS=Sugiyamaella lignohabitans GN=YUH1 PE=3 SV=1
A0A060T9L3_BLAAD53.50%2435e-87Ubiquitin carboxyl-terminal hydrolase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C38720g PE=3 SV=1
A0A1E4TEW9_9ASCO50.41%2421e-77Ubiquitin carboxyl-terminal hydrolase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_2052 PE=3 SV=1
UniRef50_A0A1E4TEW950.41%2424e-74Ubiquitin carboxyl-terminal hydrolase n=1 Tax=Tortispora caseinolytica NRRL Y-17796 TaxID=767744 RepID=A0A1E4TEW9_9ASCO
A0A1E3PE81_9ASCO45.53%2465e-69Ubiquitin carboxyl-terminal hydrolase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_53182 PE=3 SV=1
Q6C1J7_YARLI46.31%2445e-67Ubiquitin carboxyl-terminal hydrolase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F15697g PE=3 SV=1
A0A0J9XCS9_GEOCN44.94%2672e-64Ubiquitin carboxyl-terminal hydrolase OS=Geotrichum candidum GN=BN980_GECA09s03739g PE=3 SV=1
A0A1D8PDR9_CANAL43.90%2056e-51Ubiquitin carboxyl-terminal hydrolase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.6272 PE=3 SV=1
UBL1_YEAST35.89%2485e-39Ubiquitin carboxyl-terminal hydrolase YUH1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YUH1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0266

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 247

Detailed signature matches

  1. Domain IPR001578
    Peptidase C12, ubiquitin carboxyl-terminal hydrolase
    1. PR00707 (UBCTHYDRLASE)
    2. PF01088 (Peptidase_C12)
    3. G3DSA:3.40.53...
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF54001 (Cysteine ...)
  2. cd09616 (Peptidase_...)

Residue annotation

  1. inhibitor binding ...
  2. peptide binding si...
  3. catalytic site cd0...

Protein sequence

>MCA_03040_1
MPPKALVPLESNPDVFNKLANSLGLSEEYSFCDVFSIDDPDLLSFVPRPVYALILVFPVSDTYEKYRKEQDSKLPTDYYN
SISGDQDKEDALWYKQTIKNACATFAILHALTNGVPSSGLKKDSYIDKFIKSTITENMEQRIKHLENDEELRKFHSSVAN
AGNTEMPDAEEDVELHYVCFTKSRKLGHLVELDGRRTGPVDLGAFDDSTDEIQDILSEKALNHVRGFIQREPNNPNFSML
ALTKSLL

GO term prediction

Biological Process

GO:0006511 ubiquitin-dependent protein catabolic process

Molecular Function

GO:0004843 thiol-dependent ubiquitin-specific protease activity

Cellular Component

GO:0005622 intracellular