Protein
MCA_03010_1
Length
683 amino acids
Gene name: MDV1
Description: Mitochondrial division protein 1; Saccharomyces cerevisiae homologue is a peripheral protein of cytosolic face of mitochondrial outer membrane; required for mitochondrial fission; interacts with Fis1p and with the self-assembled oligomeric form of the dynamin-related GTPase Dnm1p; contains WD repeats; MDV1 has a paralog, CAF4, that arose from the whole genome duplication and seems to be missing from M. capitatus genome
Browser: contigB:3073613-3075665+
RNA-seq: read pairs 1447, FPKM 26.1, percentile rank 48.8% (100% = highest expression)
Protein function
| Annotation: | MDV1 | Mitochondrial division protein 1; Saccharomyces cerevisiae homologue is a peripheral protein of cytosolic face of mitochondrial outer membrane; required for mitochondrial fission; interacts with Fis1p and with the self-assembled oligomeric form of the dynamin-related GTPase Dnm1p; contains WD repeats; MDV1 has a paralog, CAF4, that arose from the whole genome duplication and seems to be missing from M. capitatus genome | |
|---|---|---|---|
| KEGG: | K17970 | MDV1 | mitochondrial division protein 1 |
| EGGNOG: | 0QE49 | MDV1 | Involved in mitochondrial fission. Acts as an adapter protein required to form mitochondrial fission complexes. Formation of these complexes is required to promote constriction and fission of the mitochondrial compartment at a late step in mitochondrial division (By similarity) |
| SGD closest match: | S000003648 | MDV1 | Mitochondrial division protein 1 |
| CGD closest match: | CAL0000173973 | CAALFM_CR04450CA | Chromatin modification protein |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| A0A0J9X6R0_GEOCN | 62.85% | 646 | 0.0 | Similar to Saccharomyces cerevisiae YJL112W MDV1 Peripheral protein of the cytosolic face of the mitochondrial outer membrane OS=Geotrichum candidum GN=BN980_GECA04s00142g PE=4 SV=1 |
| UniRef50_A0A0J9X6R0 | 62.85% | 646 | 0.0 | Similar to Saccharomyces cerevisiae YJL112W MDV1 Peripheral protein of the cytosolic face of the mitochondrial outer membrane n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X6R0_GEOCN |
| MIA_03062_1 | 63.10% | 645 | 0.0 | MIA_03062_1 |
| A0A167CAW9_9ASCO | 50.15% | 666 | 0.0 | Mdv1p OS=Sugiyamaella lignohabitans GN=MDV1 PE=4 SV=1 |
| A0A060TIB7_BLAAD | 47.61% | 586 | 2e-176 | ARAD1D37532p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D37532g PE=4 SV=1 |
| A0A1E3PLK3_9ASCO | 44.29% | 630 | 9e-174 | WD40 repeat-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_32710 PE=4 SV=1 |
| A0A1E4TGS3_9ASCO | 46.15% | 598 | 3e-159 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_113961 PE=4 SV=1 |
| MDV1_YARLI | 57.93% | 347 | 3e-132 | Mitochondrial division protein 1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=MDV1 PE=3 SV=1 |
| MDV1_YEAST | 34.42% | 520 | 2e-86 | Mitochondrial division protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MDV1 PE=1 SV=1 |
| A0A1D8PSS1_CANAL | 25.70% | 249 | 3e-20 | Chromatin modification protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CAALFM_CR04450CA PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0183
Protein family membership
None predicted.
Domains and repeats
-
Domain
-
Repeat
-
Repeat
1
100
200
300
400
500
600
683
Detailed signature matches
no IPR
Unintegrated signatures
-
-
-
-
cd00200 (WD40)
-
mobidb-lite (disord...)
Residue annotation
-
structural tetrad ...
Protein sequence
>MCA_03010_1 MSKLPDSAEIAAVKDFDVLGSASNTRISGGLNPSTATSDAFAAMAAANSNLTKFGRTVTTTASTLVSSQYPDLSGTLYHD TMKDIIHKPAFKKRFFSFSRRAPSEVMRSTLSSKEDIKYRAITAIPEELFSQIPRINNQFSLFQGFQATTATLGLDQTDL DNLRTKTLTDGTTLGKPSRKKLLKEKDVIEHTLDLLEIRKDLAANEINEIDTKILYLQSNREIVFERVASLEQEEFQLEN KMRHINMQLELISDDEDDEDDAQNENDDSNLDVKNNSAGSKSAVPSSDGKKAKGKIQQQNDSELDLSNTDQDEPLLSKSI FGKLSQSKQQNENSSNSKTKFRRQSTSHRKTQPTLQQYYHPGDSIRTIKAHDDAITALQFDIPFGTMVSASVDDTCKVWD LGRGICLGQLKGHNAYVTCAHMDNNLLVTGSMDAAAKLWDLSSLDFDESEDYCVQTFESHLREITALHFHNDTLITGSAD KTLRQWDLRSGRCLQTLDVLWAAAQSSSMPFSDNSSWKGQSSNYTTSNTSSAPFVGAVQCFDAALATGTADGIVRLWDLR SGQVQRSLIGHTGPVSCLQFDDMYLTTGSLDRSIRMWDLRMGSIVDAYSYDSPITSLQFDARKIVSTNNENTIKIYDRET GQHWTCGPGVKDPESKESIQFAMFKEGYIVEGRSNGTIGAWAC
GO term prediction
Biological Process
None predicted.
Molecular Function
GO:0005515 protein binding
Cellular Component
None predicted.