Protein

MCA_02978_1

Length
1,470 amino acids


Gene name: RPO41A

Description: DNA-directed RNA polymerase, mitochondrial

Browser: contigB:2992180-2996652-

RNA-seq: read pairs 1366, FPKM 11.5, percentile rank 28.4% (100% = highest expression)

Protein function

Annotation:RPO41ADNA-directed RNA polymerase, mitochondrial
KEGG:K10908POLRMT DNA-directed RNA polymerase, mitochondrial [EC:2.7.7.6]
EGGNOG:0PJAJRPO41DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
SGD closest match:S000001858RPO41DNA-directed RNA polymerase, mitochondrial
CGD closest match:CAL0000185076RPO41DNA-directed RNA polymerase

Protein alignments

%idAln lengthE-value
MIA_02549_160.42%13970.0MIA_02549_1
A0A0J9X9D3_GEOCN52.28%13790.0DNA-directed RNA polymerase OS=Geotrichum candidum GN=BN980_GECA05s01335g PE=3 SV=1
UniRef50_A0A0J9X9D352.28%13790.0DNA-directed RNA polymerase n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X9D3_GEOCN
A0A167E4J0_9ASCO51.73%11540.0DNA-directed RNA polymerase OS=Sugiyamaella lignohabitans GN=RPO41 PE=3 SV=1
A0A060T4A8_BLAAD45.42%13100.0DNA-directed RNA polymerase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B01804g PE=3 SV=1
A0A1E3PUP0_9ASCO46.00%12890.0DNA-directed RNA polymerase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_30998 PE=3 SV=1
RPOM_YEAST45.67%12000.0DNA-directed RNA polymerase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RPO41 PE=3 SV=2
A0A1D8PCA4_CANAL39.75%11850.0DNA-directed RNA polymerase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=RPO41 PE=3 SV=1
A0A1E4TGB0_9ASCO37.07%13730.0DNA-directed RNA polymerase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_31657 PE=3 SV=1
Q6CH64_YARLI37.99%11660.0DNA-directed RNA polymerase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_A12001g PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.5802
Predicted cleavage: 36

Protein family membership

Domains and repeats

1 200 400 600 800 1000 1200 1470

Detailed signature matches

    1. PS00489 (RNA_POL_PH...)
    2. PF00940 (RNA_pol)
    3. PS00900 (RNA_POL_PH...)
    1. SM01311 (RPOL_N_2)
    2. PF14700 (RPOL_N)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF56672 (DNA/RNA p...)
  2. mobidb-lite (disord...)

Protein sequence

>MCA_02978_1
MLSAHGLSKTKRYSLAQYKLTCNRISSIITHSGRSSATFNNEFSVLLSRKFKTDAKASQAMAAPSYNSITKEPFIASNNT
ISSSPLLGSLNSNSDSTNNTSWSSSKDVISRHHFLKDFSHLWTLLEACLDSGNMTRAENVLISFSQHSREAEIVSAVNKY
LYRLVELNEQDETVAQNWLKTISSKIPMFTPNSATKAILLRNKCLATKFSKNNIELFLQINSKKCLNHIEILGVDMLAKI
LQTCNLPLSTIDPRFHTLLKIHLNQIEQQKTESLQQESKSNAESEVVASTPKDTLSELLEKASSASISQVEAIKNPKETK
EMITGFMENFNEDDIKTLDKSGVEELSSVRSYSLKTIRHALSGFTTNNEISQSIYEKALPFLSEKSSNKNNYIDFFSIFK
DLENSKDVSEAERKELYDAFEKYNYIRQRAIEKRGLEGASLKWKNSYDQMREAGAFSLKSLEAMFWEWNDSFQVVFKREL
ERIDEVLKYSSARKAADAMSKSENQDDVQDSLGLSASDRFEYGPYLSLVKPDKLGIITILELMKLSSTGGVQMGMKTAKA
VLSVGKAVEMEYRVSKASKREENILGKSGVEQLTNVSSDVNEEIKGKGINAQISWPSHIRAKIGSLLIALLINVAKVTVK
GIDPITKAAVKGKAPAFYHTYQYQNGTRLGVLKLHNSLSKYVSGDTPSNILHPQLLPMLVKPIPWTSYKTGGYLYSTNTV
MRIKDAPEQMAYLKQASDNGHLTAVYDGLNVLGNTPWTVNTDVFNVITKVWNQNKEFLEIPRDPGELVLPPAPPKGADPQ
EIRNYRRECRRIHNEHSTSYSQRCDINYKLEIARAYLGERFYFPHNMDFRGRAYPLSPHLNHLGNDLSRSLLKFWNGRKL
GSAGLRWLKIHTANVFGYDKFSFEEREQFINDHLEEIRDSALHPLDGKGWWQEGSDPWQTLAACIELNNALSCENPEEFV
SHLPVHQDGTCNGLQHYAALGGDVEGARQVNLAPSDRPQDVYAKVLEIVQRLVNQDAEKGDPIAVLLKDQLARKVIKQTV
MTTVYGVTFIGARAQIASQLKDKEGVSKENIFSCSIYITKKVFQAVRELFEGAHLIQDWLGDSATKIAKSIRLDIDSSNK
KNGNRPDFMSSVIWTTPLGLPIVQPYRQLRKVQVTTKLQTVVLTDPYALRGVNARKQKTAFPPNYVHSLDASHMLLSASE
CGRQNLDFASVHDSYWTHAADVDKMNKILRDAFIELHQVDLVSQLKNEFEQRYGHMLEYVEIPRNSKVAQEVIEARQKLS
AQLHAQQQAELEEAAANGKKLTTKAKKLRSKKSGLTFEEEIAIERRRLELLASDVPSEVEEGRAMVTPFSIIEKLSDEEL
KSLINQSQENKVKKQKPLNIKSSEHEGSGYDAQDITSQLEIDEDAEEAIDEIDGIDEESSTSTKATTIPTLDDSKKGTNL
GVFVRLKIDPVPPKGDFDVRDLVKSKYFFC

GO term prediction

Biological Process

GO:0006351 transcription, DNA-templated

Molecular Function

GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity

Cellular Component

None predicted.