Protein

MCA_02760_1

Length
704 amino acids

Gene name: MTO1

Description: Mitochondrial translation optimization protein 1

Browser: contigB:2303470-2305585-

RNA-seq: read pairs 736, FPKM 12.9, percentile rank 30.7% (100% = highest expression)

Protein function

Annotation:MTO1Mitochondrial translation optimization protein 1
KEGG:K03495gidA tRNA uridine 5-carboxymethylaminomethyl modification enzyme
EGGNOG:0PF8SMTO1Mitochondrial translation optimization protein
SGD closest match:S000003205MTO1Mitochondrial translation optimization protein 1
CGD closest match:CAL0000190865MTO1tRNA modification protein

Protein alignments

%idAln lengthE-value
MIA_00906_174.24%6910.0MIA_00906_1
A0A0J9X8T7_GEOCN70.59%6800.0Similar to Saccharomyces cerevisiae YGL236C MTO1 Mitochondrial protein, forms a heterodimer complex with Mss1p OS=Geotrichum candidum GN=BN980_GECA05s04806g PE=3 SV=1
A0A167F534_9ASCO61.15%6950.0Mto1p OS=Sugiyamaella lignohabitans GN=MTO1 PE=3 SV=1
A0A1E3PP65_9ASCO61.20%6520.0Glucose-inhibited division protein A subfamily OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_73860 PE=3 SV=1
A0A060TDN9_BLAAD60.62%6170.0ARAD1D08778p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D08778g PE=3 SV=1
UniRef50_A0A0D2ITB254.65%6660.0Rhinocladiella mackenziei CBS 650.93 unplaced genomic scaffold supercont1.3, whole genome shotgun sequence n=3 Tax=Eurotiomycetes TaxID=147545 RepID=A0A0D2ITB2_9EURO
Q5A7B1_CANAL51.73%6920.0tRNA modification protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=MTO1 PE=4 SV=1
Q6C6R3_YARLI52.38%6720.0YALI0E06941p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E06941g PE=3 SV=1
A0A1E4TIB1_9ASCO55.33%6470.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_39 PE=3 SV=1
MTO1_YEAST50.83%6590.0Mitochondrial translation optimization protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MTO1 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9930
Predicted cleavage: 12

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 704

Detailed signature matches

  1. Family IPR002218
    tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related
    1. PF01134 (GIDA)
  2. Family IPR004416
    tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG
    1. MF_00129 (MnmG_GidA)
    2. TIGR00136
  3. Domain IPR023753
    FAD/NAD(P)-binding domain
    1. G3DSA:3.50.50.60
    2. SSF51905 (FAD/NAD(P...)
  4. Domain IPR026904
    GidA associated domain 3
    1. PF13932 (GIDA_assoc)
  5. SITE IPR020595
    MnmG-related, conserved site
    1. PS01280 (GIDA_1)
    2. PS01281 (GIDA_2)
Unintegrated signatures no IPR
Unintegrated signatures
  1. PR00411 (PNDRDTASEI)
  2. SM01228 (GIDA_assoc...)

Protein sequence

>MCA_02760_1
MISAFSRKVRHRSFQQLVSSSLIYQQTKSYASISQDSRQILQSAPHHDVVVIGGGHAGSEASAAAARVGAKTLLVTPKLS
NLGVCSCNPSLGGIGKGILLKEVDALDGVAGRITDKAGIHFQVLNRSRGPAVWGPRAQIDRKIYQREMQQELTNYPNLEI
KEDAVQDIIIDHSDSTQSPHGSVKGVVLESGQVISTNNVVITTGTFLSGELHIGLEVFPGGRTGEKATFGLSETLKNAGF
TMGRLKTGTPPRLASESIDYTGLMVQYPDNPATPFSYMNDQIHLIDQQVNCHMTRTNMESHKIVMDNFDKSVHIRETVKG
PRYCPSIESKIKRFNHKDSHQIWLEPEGLDTNIVYPNGISISMPADIQFQFLRTIKGLENVNMLQPGYGVEYDYVDPREL
YHSLETKRVKGLFLAGQINGTTGYEEAASQGIIAGINAGRNSLGLDPFLIKRSQGYIGVLIDDLVTKGVEEPYRMFTSRS
EFRFILRSDNADLRLTEIGRQLGAVGDKRWQRYQRDLDEYNTLLNVLKNTKHSSREWSNQLAGAFSSINAQQKDPNAQSP
LRISSTDVQRKSAFDILRIKDVHPEHLASVIPALSRSQVSNPRILEKLDIEAKYSPYIKRESNLIKAFESDENLSIPEDF
NYDLLQSLSNESKTLLQQIKPRTLGQARRIQGVTPTACIDLFRYVKSMNTPGSVPNDSRKSSGK

GO term prediction

Biological Process

GO:0002098 tRNA wobble uridine modification
GO:0008033 tRNA processing
GO:0055114 oxidation-reduction process

Molecular Function

GO:0016491 oxidoreductase activity
GO:0050660 flavin adenine dinucleotide binding

Cellular Component

None predicted.