Protein

MCA_02756_1

Length
504 amino acids

Gene name: UAP1

Description: UDP-N-acetylglucosamine diphosphorylase

Browser: contigB:2286078-2287593+

RNA-seq: read pairs 6243, FPKM 152.8, percentile rank 85.1% (100% = highest expression)

Protein function

Annotation:UAP1UDP-N-acetylglucosamine diphosphorylase
KEGG:K00972UAP1 UDP-N-acetylglucosamine/UDP-N-acetylgalactosamine diphosphorylase [EC:2.7.7.23 2.7.7.83]
EGGNOG:0PGEJUAP1UDP-N-acetylglucosamine pyrophosphorylase
SGD closest match:S000002261QRI1UDP-N-acetylglucosamine pyrophosphorylase
CGD closest match:CAL0000180804UAP1UDP-N-acetylglucosamine diphosphorylase

Protein alignments

%idAln lengthE-value
MIA_01828_166.87%5040.0MIA_01828_1
A0A0J9X3R8_GEOCN64.73%4990.0Similar to Saccharomyces cerevisiae YDL103C QRI1 UDP-N-acetylglucosamine pyrophosphorylase, catalyzes the formation of UDP-N-acetylglucosamine (UDP-GlcNAc) OS=Geotrichum candidum GN=BN980_GECA02s01583g PE=4 SV=1
A0A1E3PLP6_9ASCO60.63%5080.0Udp-n-acetylglucosamine pyrophosphorylase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82975 PE=4 SV=1
A0A161HKI1_9ASCO60.84%4980.0UDP-N-acetylglucosamine diphosphorylase OS=Sugiyamaella lignohabitans GN=QRI1 PE=4 SV=1
Q6C776_YARLI59.56%4970.0YALI0E03146p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E03146g PE=4 SV=1
A0A060TDR5_BLAAD59.92%4890.0ARAD1D02288p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D02288g PE=4 SV=1
UniRef50_A0A0F8D3A756.07%4940.0UDP-N-acetylglucosamine pyrophosphorylase n=307 Tax=Fungi TaxID=4751 RepID=A0A0F8D3A7_CERFI
A0A1E4TFM4_9ASCO55.96%4950.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_31478 PE=4 SV=1
A0A1D8PNG6_CANAL49.20%4981e-159UDP-N-acetylglucosamine diphosphorylase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=UAP1 PE=4 SV=1
UAP1_YEAST47.09%4997e-150UDP-N-acetylglucosamine pyrophosphorylase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=QRI1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0923

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 450 504

Detailed signature matches

  1. Family IPR002618
    UDPGP family
    1. PF01704 (UDPGP)
  2. Domain IPR029044
    Nucleotide-diphospho-sugar transferases
    1. G3DSA:3.90.55...
    2. SSF53448 (Nucleotid...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd04193 (UDPGlcNAc_...)
  2. mobidb-lite (disord...)

Residue annotation

  1. substrate binding ...
  2. dimerization inter...

Protein sequence

>MCA_02756_1
MSDIETLRKAYEEAGQGHVFQFWEKLSESEKNQLVSQLKSLDSPEELSQIAKDTITKFENEIANSSKKDEASTTKKDDVQ
PLPESATCSLLDESEQSVKNQQKWYNHGLELIGQNKVGVILLAGGQGTRLGSSAPKGCYDVQLPSHKSLFQLQAERIAKL
QQLAAKEGANDVIIPWYIMTSGPTRKPTEDFFKSNNYFGLKQENVVFFEQGVLPCLTTEGKIIMETPSKVAVAPDGNGGI
YKALVKGKILDDLKARGIEHVHTYCVDNCLVKVADPVFIGWAASFKSLDIGTKVVRKKHATESVGLIVSKNGRPAVIEYS
EIAKELTELPDDSDPSILKFRAANIVNHYYSTKYLSTIPEWPSSNLPFHVAHKKIPYADPNSGETIKPSSPNGIKLEQFV
FDVFPTLKFDGPDPQFAMMEVLRSQEFSPLKNAPGSKEDSPETSRAHLLAQSKGWLKAAGAIFPEDPEEDAQCEVEISPL
VSYAGEGLEKYKGHKFAKGQHYIH

GO term prediction

Biological Process

GO:0008152 metabolic process

Molecular Function

GO:0070569 uridylyltransferase activity

Cellular Component

None predicted.