Protein

MCA_02730_1

Length
888 amino acids


Gene name: SEN1B

Description: Helicase SEN1

Browser: contigB:2204101-2206896+

RNA-seq: read pairs 26, FPKM 0.4, percentile rank 6.0% (100% = highest expression)

Protein function

Annotation:SEN1BHelicase SEN1
KEGG:K10706SETX senataxin [EC:3.6.4.-]
EGGNOG:0PFUUSEN1tRNA-splicing endonuclease
SGD closest match:S000004422SEN1Helicase SEN1
CGD closest match:CAL0000183795SEN1Putative DNA/RNA helicase

Protein alignments

%idAln lengthE-value
A0A060TAU8_BLAAD31.63%8033e-96ARAD1D26598p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D26598g PE=4 SV=1
UniRef50_A0A060TAU831.63%8036e-93ARAD1D26598p n=1 Tax=Blastobotrys adeninivorans TaxID=409370 RepID=A0A060TAU8_BLAAD
MIA_03901_135.63%6231e-92MIA_03901_1
A0A1E3PFB1_9ASCO35.07%6331e-92p-loop containing nucleoside triphosphate hydrolase protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_7636 PE=4 SV=1
Q5ANG6_CANAL34.72%6257e-90Putative DNA/RNA helicase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SEN1 PE=4 SV=1
A0A0J9X8S5_GEOCN30.58%8118e-89Similar to Saccharomyces cerevisiae YLR430W SEN1 Presumed helicase required for RNA polymerase II transcription termination and processing of RNAs OS=Geotrichum candidum GN=BN980_GECA06s00615g PE=4 SV=1
SEN1_YEAST34.25%6541e-87Helicase SEN1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SEN1 PE=1 SV=2
W0TYQ4_YARLI33.83%6744e-86YALI0A19404p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_A19404g PE=4 SV=1
A0A167CSC4_9ASCO32.50%5603e-78Putative DNA/RNA helicase SEN1 OS=Sugiyamaella lignohabitans GN=SEN1 PE=4 SV=1
A0A1E4THA5_9ASCO28.94%8127e-81Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_12256 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2471

Protein family membership

None predicted.

Domains and repeats

1 100 200 300 400 500 600 700 800 888

Detailed signature matches

    1. SSF52540 (P-loop co...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. PF13086 (AAA_11)
  2. PF13087 (AAA_12)
  3. cd00046 (DEXDc)

Residue annotation

  1. ATP binding site c...

Protein sequence

>MCA_02730_1
MARDSNNLVKEITEYSQSLRLSPSQQNPCELKPDIIKEIITWDPYNRSDIPRIRNRKPKIKFENLKDIPDGSCLIDNYIE
IISNLAKIEFWKSIQNEIKYEPEIEFDITIQSTKKGYTGKISNITKFGIPFQIETIETENEDEDEDEEGIIKQDDLLLVC
ETSNLGNILETAKRNGRFTFVKKVKNNICHLSNVPFSGNCYGCKANSLTTVSRQFEALYNLKNTYPKRPLFNQVLSRMPN
DVVQSSDSNIQQVAKKFKLNSSQAETLLGTTSLKGINLIQGPPGTGKTKTIAAIIAHTLLADPKKRILVCTPSNAGVNEI
VTRLVDGIPYIDPDSNTESLMKPSVVRIGRLADINEQEISYSKLRSVYLNTVFEDHAYWSQKSQDVPEFTNRELFLIFKA
MKKYIQSQFAMTVETSLRFYNSGLSNEERSESAEFSLYSKVFLNEFGVTLKRSQNPQIQTLNSLIDYCNKQIKSLLEKKK
NTIKNIGSDERENIVFQILSKTQVVCSTLAGAGHRSVYQQEEFDLIIIDEAGQAVEVDCLIPLQYKCDTCIMVGDSKQLQ
PTVFSDLAADMGYDISLFTRMAENQSNSYMLNTQYRMHPDISKFPLKQFYNNKVINGPRTSIDTIRPWHKLGHDFGTFRF
FDISDGTHRSLEYSQSIINTEEVESIVNMYDILQKNTSIDITERVGIVTPYKAQTESLKKAFEKKYGQSEAEKMFEKLEI
STVDRFQGQEKDIIMLSCVRSGSYSRNSIGFLKDPNRLNVAVTRAKSSLWVFGNGQTLSSNAMWRKMIDIAKDMRYYINA
KNSFYFFVLSHKLQPLKNQDEKLIKKSETQNCISTAKVKRLILKTELDRLSDFCLKYNTEKEKMINNGNIGKAIKNILES
YGIDWKET

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.