Protein
MCA_02703_1
Length
498 amino acids
Gene name: MCA1
Description: Metacaspase-1
Browser: contigB:2099496-2100993-
RNA-seq: read pairs 6037, FPKM 149.5, percentile rank 84.8% (100% = highest expression)
Protein function
| Annotation: | MCA1 | Metacaspase-1 | |
|---|---|---|---|
| EGGNOG: | 0PGJT | MCA1 | Involved in cell death (apoptosis) (By similarity) |
| SGD closest match: | S000005723 | MCA1 | Metacaspase-1 |
| CGD closest match: | CAL0000184470 | MCA1 | Metacaspase-1 |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_00359_1 | 77.88% | 339 | 0.0 | MIA_00359_1 |
| A0A0J9X509_GEOCN | 66.36% | 330 | 3e-163 | Similar to Saccharomyces cerevisiae YOR197W MCA1 Ca2+-dependent cysteine protease similar to mammalian metacaspases OS=Geotrichum candidum GN=BN980_GECA02s07237g PE=4 SV=1 |
| A0A1E3PRN3_9ASCO | 61.49% | 322 | 3e-147 | Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_44648 PE=4 SV=1 |
| UniRef50_G2RCM6 | 61.08% | 334 | 8e-144 | Caspase-like protein n=3 Tax=Fungi TaxID=4751 RepID=G2RCM6_THITE |
| MCA1_YARLI | 62.89% | 318 | 9e-144 | Metacaspase-1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=MCA1 PE=3 SV=1 |
| A0A060T8P4_BLAAD | 60.12% | 346 | 4e-142 | ARAD1D05060p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D05060g PE=4 SV=1 |
| MCA1_CANAL | 57.35% | 340 | 3e-135 | Metacaspase-1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=MCA1 PE=3 SV=1 |
| A0A167F838_9ASCO | 59.25% | 319 | 6e-132 | Ca(2+)-dependent cysteine protease MCA1 OS=Sugiyamaella lignohabitans GN=MCA1 PE=4 SV=1 |
| MCA1_YEAST | 57.89% | 342 | 3e-130 | Metacaspase-1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MCA1 PE=1 SV=2 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0004
Protein family membership
None predicted.
Domains and repeats
-
Domain
1
50
100
150
200
250
300
350
400
450
498
Detailed signature matches
-
-
SSF52129 (Caspase-like)
-
no IPR
Unintegrated signatures
-
-
PF00656 (Peptidase_C14)
-
mobidb-lite (disord...)
Protein sequence
>MCA_02703_1 MSYYPGGGGRTYGGQDPNSGGYSGGGYSGGGYSGGGYSGGGYNDQGGYSGGGYSDRGSNNNQDYSGGGYSGQGGYSGGGY SGGGYSGGGYNDGGYSGGGYSGGGYSQGGPPQGPPPGGYGGGGYNNGGYSSGGGYGGPPPGPPPDRTGWTTNSGWTGFQE GGYDNPNYGGSHDVSGTRFQAPPTQAQSFGVEGYNYQYSQCTGRRKALLIGINYFGQKGELKGCINDVHNVKRFLQETYG YRDEDTVVLTDDQKNPKSIPTKENIIRACQWLTRGAQPNDSLFFHYSGHGGQTEDLSGDEEDGYDEVIYPVDYARAGHIV DDTLHELLVKPLPAGARLTAIFDCCHSATALDLPYVYSTKGVLKEPNLLKDTGKSVFSALSSYSRGDIGGVMTSVTGAID RLTKGNKASEKTKKDRTSPADVIMFSGCKDNQTSADSFEDGSPTGAMSHAFLQVMRNNPNQSYLSLLNNTRDILASKYDQ KPQLSSSHPLDCNLKFIM
GO term prediction
Biological Process
None predicted.
Molecular Function
None predicted.
Cellular Component
None predicted.