Protein

MCA_02673_1

Length
436 amino acids

Gene name: AAT1

Description: aspartate aminotransferase, mitochondrial

Browser: contigB:2016016-2017327-

RNA-seq: read pairs 45683, FPKM 1291.7, percentile rank 97.1% (100% = highest expression)

Protein function

Annotation:AAT1aspartate aminotransferase, mitochondrial
KEGG:K14455GOT2 aspartate aminotransferase, mitochondrial [EC:2.6.1.1]
EGGNOG:0PGXMAAT1aspartate Aminotransferase
SGD closest match:S000004017AAT2Aspartate aminotransferase, cytoplasmic
CGD closest match:CAL0000198574AAT1Aspartate transaminase

Protein alignments

%idAln lengthE-value
MIA_02036_179.61%4070.0MIA_02036_1
A0A0J9X6F2_GEOCN75.12%4060.0Aspartate aminotransferase OS=Geotrichum candidum GN=BN980_GECA03s00780g PE=4 SV=1
A0A060TI98_BLAAD73.40%4060.0Aspartate aminotransferase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D37202g PE=4 SV=1
Q6CFZ7_YARLI72.35%4050.0Aspartate aminotransferase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B02178g PE=4 SV=1
A0A167EQL1_9ASCO72.48%4070.0Aspartate aminotransferase OS=Sugiyamaella lignohabitans GN=AAT2 PE=4 SV=1
A0A1E3PGD7_9ASCO70.12%4050.0Aspartate aminotransferase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_52914 PE=4 SV=1
UniRef50_A0A093XT5266.92%4020.0Aspartate aminotransferase n=1 Tax=Talaromyces marneffei PM1 TaxID=1077442 RepID=A0A093XT52_TALMA
A0A1E4TE53_9ASCO67.74%4030.0Aspartate aminotransferase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_99031 PE=4 SV=1
A0A1D8PHC9_CANAL46.00%4134e-128Aspartate transaminase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=AAT1 PE=4 SV=1
AATC_YEAST45.02%4023e-128Aspartate aminotransferase, cytoplasmic OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=AAT2 PE=1 SV=3

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9989
Predicted cleavage: 20

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 400 436

Detailed signature matches

  1. Family IPR000796
    Aspartate/other aminotransferase
    1. PR00799 (TRANSAMINASE)
  2. Domain IPR015424
    Pyridoxal phosphate-dependent transferase
    1. SSF53383 (PLP-depen...)
  3. Domain IPR015422
    Pyridoxal phosphate-dependent transferase, subdomain 2
    1. G3DSA:3.90.11...
  4. Domain IPR004839
    Aminotransferase, class I/classII
    1. PF00155 (Aminotran_1_2)
  5. Domain IPR015421
    Pyridoxal phosphate-dependent transferase, major region, subdomain 1
    1. G3DSA:3.40.64...
  6. SITE IPR004838
    Aminotransferases, class-I, pyridoxal-phosphate-binding site
    1. PS00105 (AA_TRANSFE...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd00609 (AAT_like)

Residue annotation

  1. pyridoxal 5'-phosp...
  2. homodimer interfac...
  3. catalytic residue ...

Protein sequence

>MCA_02673_1
MLRIASPSSRLLARSAFRSAARPLFVVPQAALKSTWAGVKAGPPDAILGITEAFKRDTFAQKINVGVGAYRDDEGKPFVL
PSVREADKRVLEKNLNKEYAPITGIPEFTSAAAQLAYGDASPVILEDRLAVTQTISGTGALRVGAEFFSRFFPFPSGKKQ
VFLPNPSWANHKNVFRDAGITPVSYRYYDSKNIALDYDGLVEDLRQAENGSLVLLHACAHNPTGVDPTPEQWRSIAEVIK
EKGHFPFFDMAYQGFASGDIAKDAYALRYFVDQGFQVALCQSFAKNMGLYGERVGAFSMVAETKEERSILDSQLKVVIRP
IYSNPPIHGARIASEILNDPKLKAQWLQEVKDMASRMIKMRSLLKENLEALGSQRDWSHVTSQIGMFCYTGLTPEQVDAL
AKDYSIYGTRDGRVSIAGITSSNVKRLAEAIHNVTK

GO term prediction

Biological Process

GO:0006520 cellular amino acid metabolic process
GO:0009058 biosynthetic process

Molecular Function

GO:0003824 catalytic activity
GO:0008483 transaminase activity
GO:0030170 pyridoxal phosphate binding

Cellular Component

None predicted.