Protein
MCA_02643_1
Length
832 amino acids
Gene name: PDE1
Description: 3',5'-cyclic-nucleotide phosphodiesterase 1
Browser: contigB:1932184-1934843-
RNA-seq: read pairs 1664, FPKM 24.7, percentile rank 47.4% (100% = highest expression)
Protein function
| Annotation: | PDE1 | 3',5'-cyclic-nucleotide phosphodiesterase 1 | |
|---|---|---|---|
| EGGNOG: | 0PFC9 | PDE1 | phosphodiesterase |
| SGD closest match: | S000003217 | PDE1 | 3',5'-cyclic-nucleotide phosphodiesterase 1 |
| CGD closest match: | CAL0000177603 | PDE1 | 3',5'-cyclic-nucleotide phosphodiesterase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_02866_1 | 55.38% | 186 | 1e-53 | MIA_02866_1 |
| A0A0J9XCP2_GEOCN | 51.02% | 147 | 8e-40 | Similar to Saccharomyces cerevisiae YGL248W PDE1 Low-affinity cyclic AMP phosphodiesterase OS=Geotrichum candidum GN=BN980_GECA10s02265g PE=4 SV=1 |
| UniRef50_A0A0J9XCP2 | 51.02% | 147 | 2e-36 | Similar to Saccharomyces cerevisiae YGL248W PDE1 Low-affinity cyclic AMP phosphodiesterase n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XCP2_GEOCN |
| Q6C3S3_YARLI | 57.45% | 94 | 7e-27 | YALI0E32527p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E32527g PE=4 SV=2 |
| A0A167D7T4_9ASCO | 52.87% | 87 | 5e-23 | 3',5'-cyclic-nucleotide phosphodiesterase OS=Sugiyamaella lignohabitans GN=PDE1 PE=3 SV=1 |
| A0A1E3PME6_9ASCO | 46.30% | 108 | 1e-21 | 3',5'-cyclic-nucleotide phosphodiesterase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_51267 PE=3 SV=1 |
| A0A060T0G9_BLAAD | 51.28% | 78 | 2e-21 | 3',5'-cyclic-nucleotide phosphodiesterase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C07612g PE=3 SV=1 |
| PDE1_YEAST | 56.06% | 66 | 8e-14 | 3',5'-cyclic-nucleotide phosphodiesterase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PDE1 PE=1 SV=2 |
| A0A1E4TIX1_9ASCO | 37.93% | 87 | 3e-12 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_59037 PE=4 SV=1 |
| Q5AGE4_CANAL | 42.03% | 69 | 3e-08 | 3',5'-cyclic-nucleotide phosphodiesterase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PDE1 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.1013
Protein family membership
- Cyclic-AMP phosphodiesterase, class-II (IPR000396)
Domains and repeats
-
Domain
1
100
200
300
400
500
600
700
832
Detailed signature matches
-
-
-
SSF56281 (Metallo-h...)
-
no IPR
Unintegrated signatures
-
mobidb-lite (disord...)
Protein sequence
>MCA_02643_1 MIRDSNTNSSLNNNSESEPEKKHAFQVVILGSNGGPMERNTSSLIVKSTSSPWSKNCLLAIDAGTLASGLLDILTNQFLL SLLIQTNNNNNNTQVSSTNNEQTATANATDLCSSTSSNAPSASLESPPPPDPDALAKSIPIQVLRAKYANLLSTSLPFRP SIYRKNLDKSLSQSSSSSSPHISKQLSDHFIFPKEALPYSKPIDNTWYIINCLLSTICITHPHLDHIAGLVINSSNFTFD NPKTVAGLPSTIDALASHVFNGIIWPNLSNEGVDPVGLFCLKRLSIENSLYYSHQYRKTNSQIPAFTNTSKQGSSTINKG PFSPSYSLTIETASNHSKLSKESIFSPSTKSPSNNSNNSSSSNSSSSSNNNNNINTHSNIPIVTTTTPPSAPSSSTDNKS NINNSTKVERKPPHFAAESLAHNLSVLPFPISHGTVCQSGIARRKSSVSGLFSLLAPSPSRHKSISHSNFNPLSGSSAGS KLQSGINTSPLVNPSPLSESHSLTSPDETVPPKEFPTVSSSSSSSSSATKTEPNVATSSAPSNKVRVMPPPPSSSSSSSS SSSSSLSLSSSSARGLLYPSPSTYISTAYFIEDNVTGQNILVWGDVEPDSKSRSPKNIHVWRHAAKLYSMNKLKAVFIEC SYAYSQEQLFGHFSTPFLIEELSNFSRIVSEVSSETCSNSSPSSSSSSSASNGHSSERCNLDNLEVFIMHVKDDDPLELC RPPLNLDHTEEDDLARRKKQKLNNGSQSIDIDSPIASTTTTTAAATTTTTSSATSIPSPTSPTNLEGIESLANDTQATTP SKVILAELKTLAKGAGLACNFQIAKPGSCIYL
GO term prediction
Biological Process
GO:0006198 cAMP catabolic process
Molecular Function
GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity
Cellular Component
None predicted.