Protein
MCA_02627_1
Length
247 amino acids
Gene name: TIF45
Description: Eukaryotic translation initiation factor 4E
Browser: contigB:1871101-1871845-
RNA-seq: read pairs 7864, FPKM 391.8, percentile rank 93.4% (100% = highest expression)
Protein function
| Annotation: | TIF45 | Eukaryotic translation initiation factor 4E | |
|---|---|---|---|
| KEGG: | K03259 | EIF4E | translation initiation factor 4E |
| EGGNOG: | 0PHEP | TIF45 | Translation Initiation Factor |
| SGD closest match: | S000005499 | CDC33 | Eukaryotic translation initiation factor 4E |
| CGD closest match: | CAL0000195194 | TIF45 | Eukaryotic translation initiation factor 4E |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| A0A0J9X6E0_GEOCN | 59.24% | 211 | 3e-79 | Similar to Saccharomyces cerevisiae YOL139C CDC33 Cytoplasmic mRNA cap binding protein and translation initiation factor eIF4E OS=Geotrichum candidum GN=BN980_GECA03s06049g PE=3 SV=1 |
| UniRef50_A0A0J9X6E0 | 59.24% | 211 | 6e-76 | Similar to Saccharomyces cerevisiae YOL139C CDC33 Cytoplasmic mRNA cap binding protein and translation initiation factor eIF4E n=3 Tax=Saccharomycetales TaxID=4892 RepID=A0A0J9X6E0_GEOCN |
| MIA_02987_1 | 61.61% | 211 | 5e-75 | MIA_02987_1 |
| A0A167DY98_9ASCO | 46.45% | 211 | 8e-57 | Translation initiation factor eIF4E OS=Sugiyamaella lignohabitans GN=CDC33 PE=3 SV=1 |
| A0A060THD7_BLAAD | 46.57% | 204 | 1e-56 | ARAD1D30096p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D30096g PE=3 SV=1 |
| A0A1E3PRB8_9ASCO | 42.52% | 214 | 4e-49 | Eukaryotic translation initiation factor 4E OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_44664 PE=3 SV=1 |
| IF4E_CANAL | 41.21% | 199 | 4e-49 | Eukaryotic translation initiation factor 4E OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=TIF45 PE=3 SV=1 |
| Q6C7Y7_YARLI | 39.90% | 208 | 5e-48 | YALI0D24299p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D24299g PE=3 SV=1 |
| IF4E_YEAST | 39.15% | 212 | 8e-44 | Eukaryotic translation initiation factor 4E OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CDC33 PE=1 SV=1 |
| A0A1E4TFW1_9ASCO | 41.41% | 198 | 9e-39 | Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_19510 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0537
Protein family membership
- Translation Initiation factor eIF- 4e-like (IPR023398)
- Translation Initiation factor eIF- 4e (IPR001040)
Domains and repeats
None predicted.
Detailed signature matches
no IPR
Unintegrated signatures
-
mobidb-lite (disord...)
Protein sequence
>MCA_02627_1 MAAVESTTQKLDNLNLNSPAEDTPSTTATTETAGTSVNADDVSPTVLNPSVDFSVIHPLSSSWTMWYIKPPTAGKGDWSD LLTEVVTFSSIEEFWGAYNNLPKVSELPMRSDYALFKTGIRPEWEDKANSKGGKIVYPFRDNSSRGSNNNSGTSRVDEIW LNILVGLLGGTLDVTNDPEVPVSEQKINGVFVNVRKAAIRFNLWTKDVEVDALKPIANRFKGLLKISVDDELELSPHDSS SRTKHTV
GO term prediction
Biological Process
GO:0006413 translational initiation
Molecular Function
GO:0003723 RNA binding
GO:0003743 translation initiation factor activity
Cellular Component
GO:0005737 cytoplasm