Protein

MCA_02621_1

Length
851 amino acids


Gene name: HSP78

Description: Heat shock protein 78, mitochondrial

Browser: contigB:1848795-1851351-

RNA-seq: read pairs 3818, FPKM 55.4, percentile rank 67.5% (100% = highest expression)

Protein function

Annotation:HSP78Heat shock protein 78, mitochondrial
KEGG:K03695clpB ATP-dependent Clp protease ATP-binding subunit ClpB
EGGNOG:0PH92HSP78Heat shock protein
SGD closest match:S000002666HSP78Heat shock protein 78, mitochondrial
CGD closest match:CAL0000189244HSP78Heat shock protein 78, mitochondrial

Protein alignments

%idAln lengthE-value
MIA_04967_184.89%7610.0MIA_04967_1
A0A0J9X456_GEOCN82.65%7320.0Similar to Saccharomyces cerevisiae YDR258C HSP78 Oligomeric mitochondrial matrix chaperone that cooperates with Ssc1p in mitochondrial thermotolerance after heat shock OS=Geotrichum candidum GN=BN980_GECA01s07633g PE=3 SV=1
A0A161HFG7_9ASCO77.00%7260.0Chaperone ATPase HSP78 OS=Sugiyamaella lignohabitans GN=HSP78 PE=3 SV=1
A0A060T1G2_BLAAD78.81%7080.0ARAD1C16236p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C16236g PE=3 SV=1
A0A1E3PEW5_9ASCO77.22%7200.0Heat shock protein 78, mitochondrial HSP78 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_47880 PE=3 SV=1
A0A1E4THQ7_9ASCO74.93%7220.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_26676 PE=3 SV=1
HSP78_YEAST72.30%7220.0Heat shock protein 78, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HSP78 PE=1 SV=2
UniRef50_P3341672.30%7220.0Heat shock protein 78, mitochondrial n=839 Tax=cellular organisms TaxID=131567 RepID=HSP78_YEAST
HSP78_CANAL69.79%7250.0Heat shock protein 78, mitochondrial OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=HSP78 PE=3 SV=2
Q6C1Y2_YARLI70.78%7220.0YALI0F12463p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F12463g PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9976
Predicted cleavage: 97

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 700 800 851

Detailed signature matches

    1. PR00300 (CLPPROTEASEA)
    1. SSF52540 (P-loop co...)
    1. SM00382 (AAA_5)
    1. PF00004 (AAA)
    2. PF07724 (AAA_2)
    1. PF10431 (ClpB_D2-small)
    2. SM01086 (ClpB_D2_sm...)
    1. PS00870 (CLPAB_1)
    1. PS00871 (CLPAB_2)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd00009 (AAA)
  2. mobidb-lite (disord...)

Residue annotation

  1. Walker A motif cd0...
  2. ATP binding site c...
  3. Walker B motif cd0...
  4. arginine finger cd...
  5. Walker A motif cd0...
  6. ATP binding site c...
  7. Walker B motif cd0...
  8. arginine finger cd...

Protein sequence

>MCA_02621_1
MNRIASSKSALRQLSSVTSRQLASRRVNTNILNPDIPVLLLQQQQSRNLSTTQSSTLTRNSNRQSLLRLHRPAITAKRYY
ASNNNNNNNGGFNFRMNPNQQGAEPEKSALEQYGVDLTKMAQEGKLDAVIGRDEEIRRTIQILSRRTKNNPALIGNAGTG
KTAIMEGLAQRIVRGEVPESMKDKKVIALDLGSLISGAKFRGDFEERLKNVLKEVDEANGKIILFIDELHILLGLGKAEG
AVDASNLLKPALARGQLQCCGATTIEEYRKYIEKDAALARRFQPVMVAEPTVPDTISILRGLKERYEVHHGVRITDAALV
TAAVYSNRYITDRFLPDKAIDLVDEACSALRLQHESKPDVIQQLDRQIMTIQIELESLKKETDPISVERREALQDQLKAK
QAEVERLTQVWEKERKEIEEVKNAKANLEQARLNLEIAQRNGDFAKASELQYSIIPSLIAKLPKESKNNQEGDTLLHDSV
TSEDIAAVVSRMTGIPTQSLMKGEKDKLLYMEESLKGRVVGQDEAIHAIADAVRLQRAGLTNEKRPVGSFMFLGPTGTGK
TELTKALAQFLFDDESAVVRFDMSEFQERHTVSRLIGSPPGYVGYEESGELTEAVRRKPYAVVLFDEFEKAHPDVSKLLL
QVLDEGKLTDSKGTKVDFRNTIIVMTSNIGQDILIADEEVNRDESGKVPEEAKNKVIDVMKQYYPPEFINRLDDIVVFNR
LSKQSLRKIVDIRLGEVAERLVSRRIALDVSPEAKDWLAEHGYEPRFGARPLNRLIQKQLLNPLAMHLIKGLVRSNETVK
VVVEDGKLKVLPNHESGPEEGESETIDHDEVHGRIEEDDGDIIDIPDNSQK

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0005524 ATP binding

Cellular Component

None predicted.