Protein

MCA_02609_1

Length
786 amino acids

Gene name: ORC1

Description: Origin recognition complex subunit 1

Browser: contigB:1807895-1810256-

RNA-seq: read pairs 1102, FPKM 17.3, percentile rank 37.5% (100% = highest expression)

Protein function

Annotation:ORC1Origin recognition complex subunit 1
KEGG:K02603ORC1 origin recognition complex subunit 1
EGGNOG:0PHW5ORC1Origin recognition complex subunit
SGD closest match:S000004530ORC1Origin recognition complex subunit 1
CGD closest match:CAL0000190220ORC1Origin recognition complex subunit 1

Protein alignments

%idAln lengthE-value
A0A0J9XE66_GEOCN55.41%4719e-169Similar to Saccharomyces cerevisiae YML065W ORC1 Largest subunit of the origin recognition complex OS=Geotrichum candidum GN=BN980_GECA12s00538g PE=4 SV=1
UniRef50_A0A0J9XE6655.41%4712e-165Similar to Saccharomyces cerevisiae YML065W ORC1 Largest subunit of the origin recognition complex n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XE66_GEOCN
MIA_04427_151.59%5044e-166MIA_04427_1
A0A167C2H4_9ASCO54.61%4014e-146Origin recognition complex subunit 1 OS=Sugiyamaella lignohabitans GN=ORC1 PE=4 SV=1
A0A060TFZ7_BLAAD49.16%4781e-145ARAD1D27104p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D27104g PE=4 SV=1
Q6C9L7_YARLI50.81%4335e-145YALI0D10104p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D10104g PE=4 SV=1
A0A1E3PGG4_9ASCO50.80%4357e-139Origin recognition complex subunit 1 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_26198 PE=4 SV=1
A0A1D8PCY1_CANAL46.32%4215e-119Origin recognition complex subunit 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ORC1 PE=4 SV=1
ORC1_YEAST35.01%4974e-84Origin recognition complex subunit 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ORC1 PE=1 SV=1
A0A1E4TB41_9ASCO38.11%4122e-81Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_57953 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0044

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 700 786

Detailed signature matches

  1. Domain IPR001025
    Bromo adjacent homology (BAH) domain
    1. SM00439 (BAH_4)
    2. PS51038 (BAH)
    3. PF01426 (BAH)
  2. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  3. Domain IPR003593
    AAA+ ATPase domain
    1. SM00382 (AAA_5)
  4. Domain IPR003959
    ATPase, AAA-type, core
    1. PF00004 (AAA)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:1.10.8.60
  3. G3DSA:3.40.50...
  4. SSF82061 (BAH domain)
  5. cd00009 (AAA)
  6. mobidb-lite (disord...)

Residue annotation

  1. Walker A motif cd0...
  2. ATP binding site c...
  3. Walker B motif cd0...
  4. arginine finger cd...

Protein sequence

>MCA_02609_1
MNEERLEWEYYYEDGNHVSSTQPANRNTRSLRGAASPNPIAVVRKQDNVRFQIGDDVLLESEDPDDPFVGRIHGFDYSST
GFVEVIIQWYSRNKDIPTKYQRPDYAPNELYFTIDTDKNDIETLINHCSVLSPEKYRTSTDPVKYFVQYGFNSSTGSFTD
PIDWSELTKIPQHKLFEVLRPIMDKTIKNTSTSSKKNVSEVPAQPQDVFSRSKSPEESLKKADSPPLKRKRGRAKKDTTK
PVNAEEPKKRGRKKKEELPLDEDEDVVLVEPEDQSMNLPESSGVESAYEESENEQEEYDEEEDDFEAEEVPKSKRSPRKT
QPTSRSPKKQTSRQSTKTEPNIQSKNMKNLIMIRSRAPRRMVQKATFSVRPLPQKSDDLIEKSAQQVNDYDKIRDILHVS
SVPDALPCREKEYSRIYLCLDGAIRQGTGTCLYVNGTPGTGKTATVREVILQLQMTTQMEGKNRLPPFSCLEINGMKLIN
PAEAYEILWHHISGVRVSAANAAGLLEQEFKSPKNKNRQPIVVLMDELDQLVTKNQNVMYNFFNWPSLPESQLIVIAISN
TMDLPERILTNKISSRMGLTRITFEGYKYEQLIQIITARLNKYGHIFQPEAIELASRKVASVNGDARRALDFCRRAVELA
LEDPDNKDDGTVKFKHVKMAIDETTNSPMFIYLQELPFSSKILLSAVMARIRRSGINENPMSDIIEETQQLCKISKQSEK
IMRVLYENGTRIRMNGLTKSIAELVEGGILIQQNMKGERCPKIRLAIAQEEIKMAFRTDRDMDTLI

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003682 chromatin binding
GO:0005524 ATP binding

Cellular Component

None predicted.