Protein

MCA_02608_1

Length
253 amino acids

Gene name: TEM1

Description: Protein TEM1

Browser: contigB:1806982-1807744+

RNA-seq: read pairs 1235, FPKM 60.1, percentile rank 69.3% (100% = highest expression)

Protein function

Annotation:TEM1Protein TEM1
KEGG:K06682TEM1 Gtp-binding protein of the ras superfamily involved in termination of M-phase
EGGNOG:0PG6J(GTP)-binding protein
SGD closest match:S000004529TEM1Protein TEM1
CGD closest match:CAL0000197426TEM1Ras family GTPase

Protein alignments

%idAln lengthE-value
A0A0J9XKA3_GEOCN85.64%1955e-125Similar to Saccharomyces cerevisiae YML064C TEM1 GTP-binding protein of the ras superfamily involved in termination of M-phase OS=Geotrichum candidum GN=BN980_GECA22s00571g PE=4 SV=1
MIA_04426_195.34%1932e-122MIA_04426_1
A0A060TAH6_BLAAD85.49%1931e-123ARAD1D27082p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D27082g PE=4 SV=1
A0A161HIY7_9ASCO78.38%2225e-119Ras family GTPase TEM1 OS=Sugiyamaella lignohabitans GN=TEM1 PE=4 SV=1
Q6CAF7_YARLI85.20%1962e-116YALI0D03157p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D03157g PE=4 SV=1
A0A1E3PHT8_9ASCO83.70%1843e-116Septum-promoting GTP-binding protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83491 PE=4 SV=1
UniRef50_U9T6Q478.01%1918e-112Uncharacterized protein n=41 Tax=Eukaryota TaxID=2759 RepID=U9T6Q4_RHIID
A0A1D8PCX9_CANAL77.66%1972e-113Ras family GTPase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=TEM1 PE=4 SV=1
A0A1E4TBH0_9ASCO69.11%1918e-103Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_58124 PE=4 SV=1
TEM1_YEAST59.49%1954e-87Protein TEM1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TEM1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0640

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 253

Detailed signature matches

  1. Family IPR001806
    Small GTPase superfamily
    1. PF00071 (Ras)
  2. Family IPR035432
    Small GTPase, Tem1/Spg1
    1. cd04128 (Spg1)
    2. PIRSF037527 (GTPase...)
  3. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  4. Domain IPR005225
    Small GTP-binding protein domain
    1. TIGR00231
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.30.70...
  2. G3DSA:3.40.50...
  3. PR00449 (RASTRNSFRMNG)
  4. PS51419 (RAB)
  5. SM00173 (ras_sub_4)
  6. SM00174 (rho_sub_3)
  7. SM00175 (rab_sub_5)
  8. mobidb-lite (disord...)

Residue annotation

  1. Rab subfamily moti...
  2. G1 box cd04128
  3. GTP/Mg2+ binding s...
  4. Rab subfamily moti...
  5. Switch I region cd...
  6. putative GEF inter...
  7. G2 box cd04128
  8. Rab family motif 1...
  9. putative GDI inter...
  10. putative effector ...
  11. Rab family motif 2...
  12. G3 box cd04128
  13. Switch II region c...
  14. Rab family motif 3...
  15. Rab family motif 4...
  16. Rab family motif 5...
  17. Rab subfamily moti...
  18. G4 box cd04128
  19. G5 box cd04128
  20. Rab subfamily moti...

Protein sequence

>MCA_02608_1
MSSSPSPSRQHRHSNHSHHPSTSSIGSNNHETTTEPSASTTNLSQPPPELKPSVDLTPPQKQSVSLKIGLIGDAQIGKTS
LMVKYVEGDYDEDYIQTLGVNFMERKVTIRNTEITFSIWDLGGQREFVNMLPLVSNEAVAILFMFDLTRKSTLNSVKEWY
RQARGFNKTAIPFLVGTKFDLFAELPTEEQDEITRQAKKFAKAMKASLVFCSTSHSINVQKIFKIVLSKAFDLKLTLPEL
TEAGEPILIYQQW

GO term prediction

Biological Process

GO:0007049 cell cycle

Molecular Function

GO:0003924 GTPase activity
GO:0005525 GTP binding

Cellular Component

GO:0005816 spindle pole body