Protein

MCA_02606_1

Length
256 amino acids


Gene name: UBC12

Description: NEDD8-conjugating enzyme UBC12

Browser: contigB:1803465-1804363+

RNA-seq: read pairs 2444, FPKM 117.5, percentile rank 81.4% (100% = highest expression)

Protein function

Annotation:UBC12NEDD8-conjugating enzyme UBC12
KEGG:K10579UBE2M ubiquitin-conjugating enzyme E2 M
EGGNOG:0PN5ZUBC12NEDD8-conjugating enzyme UBC12
SGD closest match:S000004297UBC12NEDD8-conjugating enzyme UBC12
CGD closest match:CAL0000180912orf19.5411NEDD8-conjugating protein

Protein alignments

%idAln lengthE-value
MIA_04424_171.60%1622e-84MIA_04424_1
UniRef50_A7EEW661.69%1544e-65Uncharacterized protein n=11 Tax=Dikarya TaxID=451864 RepID=A7EEW6_SCLS1
A0A060TAW7_BLAAD61.44%1534e-68ARAD1D27038p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D27038g PE=3 SV=1
UBC12_YARLI61.04%1544e-67NEDD8-conjugating enzyme UBC12 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=UBC12 PE=3 SV=1
A0A1E4TCP1_9ASCO60.38%1594e-67Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_45947 PE=3 SV=1
A0A0J9XJG8_GEOCN61.04%1543e-66Similar to Saccharomyces cerevisiae YLR306W UBC12 Enzyme that mediates the conjugation of Rub1p OS=Geotrichum candidum GN=BN980_GECA22s00604g PE=3 SV=1
A0A1E3PDG5_9ASCO56.41%1564e-57NEDD8-conjugating enzyme UBC12 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_53526 PE=3 SV=1
Q5A7Q5_CANAL48.12%1606e-52NEDD8-conjugating protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.5411 PE=3 SV=1
UBC12_YEAST44.44%1621e-46NEDD8-conjugating enzyme UBC12 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=UBC12 PE=1 SV=1
A0A161HN35_9ASCO39.00%1001e-23E2 ubiquitin-conjugating protein UBC4 OS=Sugiyamaella lignohabitans GN=UBC4 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1354
Predicted cleavage: 85

Protein family membership

None predicted.

Domains and repeats

1 50 100 150 200 256

Detailed signature matches

    1. SSF54495 (UBC-like)
    1. PS50127 (UBIQUITIN_...)
    2. cd00195 (UBCc)
    3. PF00179 (UQ_con)
    1. PS00183 (UBIQUITIN_...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SM00212 (ubc_7)
  2. mobidb-lite (disord...)

Residue annotation

  1. E3 interaction res...
  2. Ub thioester inter...
  3. active site cystei...

Protein sequence

>MCA_02606_1
MVQGYVSTLHILSLKKKQQQEAAAAAAANSGTTSPEPGTNATNTPLSSTSSLVSNSNAPSNTLGTSSSTAANSSTSLSST
ATRRSGNSGSSFALLRLQKDFSDLNLPSTMKLSFPEGERNLMDFDVYITPDEGIYKDGTFKFTINVPQGFPHEPPKVHCT
QKIYHPNIDLEGHVCLNILRQDWKPVLSIESALIGLQFLFLEPNPNDPLNKEAATEFVDNRTAFKNSARTAMAGGTVHGQ
RFDNVLGSKARNQYYY

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.