Protein

MCA_02592_1

Length
555 amino acids

Gene name: PCK1

Description: Phosphoenolpyruvate carboxykinase (ATP)

Browser: contigB:1767024-1768692+

RNA-seq: read pairs 113418, FPKM 2520.5, percentile rank 98.1% (100% = highest expression)

Protein function

Annotation:PCK1Phosphoenolpyruvate carboxykinase (ATP)
KEGG:K01610E4.1.1.49 phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]
EGGNOG:0PI78PCK1phosphoenolpyruvate carboxykinase
SGD closest match:S000001805PCK1Phosphoenolpyruvate carboxykinase (ATP)
CGD closest match:CAL0000178446PCK1Phosphoenolpyruvate carboxykinase

Protein alignments

%idAln lengthE-value
MIA_01041_187.05%5560.0MIA_01041_1
Q6CBN4_YARLI80.98%5520.0YALI0C16995p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C16995g PE=3 SV=1
A0A060TBI2_BLAAD80.65%5530.0ARAD1D32010p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D32010g PE=3 SV=1
A0A1E4TC84_9ASCO81.51%5570.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_32618 PE=3 SV=1
A0A167D4P6_9ASCO80.07%5570.0Phosphoenolpyruvate carboxykinase PCK1 OS=Sugiyamaella lignohabitans GN=PCK1 PE=3 SV=1
A0A1E3PSB9_9ASCO77.76%5530.0ATP-utilizing phosphoenolpyruvate carboxykinase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_48970 PE=3 SV=1
UniRef50_A0A1J7IAN574.91%5500.0Phosphoenolpyruvate carboxykinase n=3 Tax=Eukaryota TaxID=2759 RepID=A0A1J7IAN5_9PEZI
A0A1D8PRM7_CANAL74.22%5160.0Phosphoenolpyruvate carboxykinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PCK1 PE=3 SV=1
PCKA_YEAST69.50%5180.0Phosphoenolpyruvate carboxykinase (ATP) OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PCK1 PE=1 SV=2
A0A0J9X912_GEOCN88.15%2112e-127Similar to Saccharomyces cerevisiae YKR097W PCK1 Phosphoenolpyruvate carboxykinase, partial (Partial) (Fragment) OS=Geotrichum candidum GN=BN980_GECA05s06318g PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0492

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 555

Detailed signature matches

  1. Family IPR001272
    Phosphoenolpyruvate carboxykinase, ATP-utilising
    1. cd00484 (PEPCK_ATP)
    2. PIRSF006294 (PEP_cr...)
    3. PF01293 (PEPCK_ATP)
    4. TIGR00224
    5. MF_00453 (PEPCK_ATP)
  2. Domain IPR008210
    Phosphoenolpyruvate carboxykinase, N-terminal
    1. G3DSA:3.40.44...
    2. SSF68923 (PEP carbo...)
  3. Domain IPR013035
    Phosphoenolpyruvate carboxykinase, C-terminal
    1. G3DSA:3.90.22...
  4. SITE IPR015994
    Phosphoenolpyruvate carboxykinase (ATP), conserved site
    1. PS00532 (PEPCK_ATP)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF53795 (PEP carbo...)

Residue annotation

  1. substrate-binding ...
  2. active site cd00484
  3. metal-binding site...
  4. ATP binding site c...

Protein sequence

>MCA_02592_1
MAPVNQTRLHPSGVDTTHSHTELEEELNEVAHIDYNKVTITHNPPAAILYEDALVYESGSAITSTGALFATSGKKTGRSP
KDKRIVDEPSSSEHVWWGPVNKKLSEQSWMINRERALDYLNTRKRIYVIDAYAGWDPKYRLKVRIVCARAYHALFMRNML
IRPTEEELANFGKPDFTIYNAGAFPANRYTTGMTSSTSVDINFKEMEMVILGTEYAGEMKKGIFTVMFYVQPVKYNNLTL
HSSANQDADKNVTLFFGLSGTGKTTLSADPNRYLIGDDEHVWTDDGVFNIEGGCYAKCVGLSAEKEPDIFNAIKFGSVLE
NVVFDSATRVVDYDDVTLTENTRCSYPIEYIPNALIPCVTENHPSNIVLLTCDARGVIPPISKLTNEQVMYHFISGYTSK
MAGTEEGVTEPEATFSACFGQPFLVLHPMKYAQMLSDKISKYNADAWLLNTGWVGGSAAKGAQRCPLKYTRAILDAIHSG
ELAKVEYEDFPVFNLKVPKTAPGVPSELLNPAKSWTGSPEEFESEVKKLGGLFVENFKTYQSGSTPEVIAAGPQL

GO term prediction

Biological Process

GO:0006094 gluconeogenesis

Molecular Function

GO:0004611 phosphoenolpyruvate carboxykinase activity
GO:0004612 phosphoenolpyruvate carboxykinase (ATP) activity
GO:0005524 ATP binding
GO:0017076 purine nucleotide binding

Cellular Component

None predicted.