Protein

MCA_02590_1

Length
378 amino acids

Gene name: OYE2C

Description: NADPH dehydrogenase 2; NADH flavin oxidoreductase NADH oxidase family protein

Browser: contigB:1755887-1757024-

RNA-seq: read pairs 8967, FPKM 292.3, percentile rank 91.6% (100% = highest expression)

Protein function

Annotation:OYE2CNADPH dehydrogenase 2; NADH flavin oxidoreductase NADH oxidase family protein
KEGG:K00354E1.6.99.1 NADPH2 dehydrogenase [EC:1.6.99.1]
EGGNOG:0PGTGFG03210.1NADH flavin oxidoreductase NADH oxidase family protein
SGD closest match:S000001222OYE2NADPH dehydrogenase 2
CGD closest match:CAL0000176070OYE22Oye22p

Protein alignments

%idAln lengthE-value
MIA_00225_160.70%3744e-169MIA_00225_1
A0A0J9XH73_GEOCN49.73%3723e-121Similar to Saccharomyces cerevisiae YHR179W OYE2 Conserved NADPH oxidoreductase containing flavin mononucleotide (FMN) OS=Geotrichum candidum GN=BN980_GECA16s01099g PE=4 SV=1
A0A167DHV9_9ASCO50.00%3808e-117Oye2p OS=Sugiyamaella lignohabitans GN=OYE2 PE=4 SV=1
A0A060TFD9_BLAAD46.70%3791e-111ARAD1D22418p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D22418g PE=4 SV=1
UniRef50_A0A1E3NVC346.58%3808e-107Uncharacterized protein n=6 Tax=Saccharomycetales TaxID=4892 RepID=A0A1E3NVC3_WICAO
Q6C0L5_YARLI45.33%3751e-109YALI0F23661p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F23661g PE=4 SV=1
OYE2_YEAST47.12%3822e-103NADPH dehydrogenase 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=OYE2 PE=1 SV=3
A0A1E3PIH8_9ASCO41.79%3901e-98NADH:flavin oxidoreductase/NADH oxidase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46861 PE=4 SV=1
Q5A894_CANAL42.30%3832e-91Oye22p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=OYE22 PE=4 SV=1
A0A1E4TKU7_9ASCO42.29%3768e-77Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_22517 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.5492
Predicted cleavage: 34

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 378

Detailed signature matches

  1. Domain IPR013785
    Aldolase-type TIM barrel
    1. G3DSA:3.20.20.70
  2. Domain IPR001155
    NADH:flavin oxidoreductase/NADH oxidase, N-terminal
    1. PF00724 (Oxidored_FMN)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF51395 (FMN-linke...)
  2. cd02933 (OYE_like_FMN)

Residue annotation

  1. active site cd02933
  2. FMN binding site c...
  3. substrate binding ...
  4. catalytic residue ...

Protein sequence

>MCA_02590_1
MSKALAALFKPLKVGTIEISQRIAFSPCTRCRAEVNGLPNDRMVTYYEQRASTPGTLLVTEATFITERAGGFKYVPGIWS
KEQIAAWQKVTSAVHNKKSSIFMQLWAPGRQSSHVTLKELGHDYISSSPLRDETDAQAPLSGYQNTETPRALTIPEIKEY
VADYAQAAKNAVEAGFDGVEIHAGNGYLIEQFIRLSANNRTDEYGGSIPNRARFVLEVVDAITAAIGPERTAIRLTPFEV
YGGVVAGPETIPMYSYILHELELRAQKSKPLAYVHTVETVFNKTAADGTPFVLHPMEFVRYIWSGIWMRTQGFEKESAEE
YTNKDDKLIIGFGRHFISNPDLVRRLKEDLPLNNYDWSTFYSHVDEGYIDYPFYDETK

GO term prediction

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0003824 catalytic activity
GO:0010181 FMN binding
GO:0016491 oxidoreductase activity

Cellular Component

None predicted.