MCA_02574_1
Gene name: PDR5C
Description: plasma membrane ATP-binding cassette (ABC) transporter; involved in multidrug resistance
Browser: contigB:1691895-1696367+
RNA-seq: read pairs 48, FPKM 0.4, percentile rank 6.4% (100% = highest expression)
Protein function
Annotation: | PDR5C | plasma membrane ATP-binding cassette (ABC) transporter; involved in multidrug resistance | |
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EGGNOG: | 0PFN7 | PGUG_04203 | (ABC) transporter |
SGD closest match: | S000005679 | PDR5 | Pleiotropic ABC efflux transporter of multiple drugs |
CGD closest match: | CAL0000201396 | CDR4 | Cdr4p |
Protein alignments
%id | Aln length | E-value | ||
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MIA_01039_1 | 62.00% | 1421 | 0.0 | MIA_01039_1 |
A0A0J9XKE4_GEOCN | 58.20% | 1402 | 0.0 | Similar to Saccharomyces cerevisiae YDR011W SNQ2 Plasma membrane ATP-binding cassette (ABC) transporter OS=Geotrichum candidum GN=BN980_GECA23s00131g PE=3 SV=1 |
A0A060T4B5_BLAAD | 54.46% | 1447 | 0.0 | ARAD1C43582p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C43582g PE=3 SV=1 |
UniRef50_A0A060T4B5 | 54.46% | 1447 | 0.0 | ARAD1C43582p n=59 Tax=Dikarya TaxID=451864 RepID=A0A060T4B5_BLAAD |
Q6CET9_YARLI | 54.41% | 1417 | 0.0 | YALI0B12980p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B12980g PE=3 SV=1 |
A0A1E4TEV9_9ASCO | 52.74% | 1407 | 0.0 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_103973 PE=3 SV=1 |
A0A161HI40_9ASCO | 50.14% | 1460 | 0.0 | ATP-binding cassette multidrug transporter PDR5 OS=Sugiyamaella lignohabitans GN=PDR5 PE=3 SV=1 |
A0A1D8PE84_CANAL | 50.72% | 1398 | 0.0 | Cdr4p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CDR4 PE=3 SV=1 |
PDR5_YEAST | 47.80% | 1435 | 0.0 | Pleiotropic ABC efflux transporter of multiple drugs OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PDR5 PE=1 SV=1 |
A0A1E3PG12_9ASCO | 39.87% | 1362 | 0.0 | Plasma membrane ATP-binding cassette transporter OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83866 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0208
Protein family membership
None predicted.
Domains and repeats
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Domain
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Domain
Detailed signature matches
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CYTOPLASMIC_D... (C...)
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NON_CYTOPLASM... (N...)
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TRANSMEMBRANE (Tran...)
Protein sequence
>MCA_02574_1 MSEISQINHTDEIKSVYGEESQYKVASSNESVISFPASLNPIVNPYSVPLLDPHSPEFSLKAWTKQLLKIQKSDSEKYPT LELGVSFRNLGAYGFQGGSEYQKTVLTTLFDVKKLIPSFLRKNRTSNKTQILSGFDGLVKSGETCVVLGRPGAGCSTFLK SIACDTYGFYIDPSTQINYQGLSKKTIENHYYGEVIYNGEDEVHYPHLSVGDTLKFAAHARAPENRPEGISRDEYANHMR DAVMASMGLLHTMNTRVGNDYVRGVSGGERKRVSICEVILGGALLQCFDNSTRGLDSASALKFIQNAKVGAEISGSTVFI SLYQASQDAYDLFDKVTVLYLGRQIYFGRADKAKQFFENMGYVCVDRQTTADFLTSLTSPAERVVKPGYEDIVPRTPEEF ESYWKSSPEYAALIQEIEEWNAAHPLQDETKLELSQKYKSSLQSGHARAKSPYILSFWRQVGLCVSRGLKRQRVDYGMPL ASIFGNLIVSLIISSIFYNLPPDTSSFAHRSSAVFFAILFNALASILEIFALYVLRPVVEKHNKYGYYHPSAEAVASIIV EFPVKIITSLSFNLVLYFMVNLRRTVGGFFIFQLFSLFAVLTMSALFRTIAALTKSIPQSLAPASYLIFAIIATTGFVIP IADMHPWIRWINYINPVAYAFEALMINEYRNRFFECNQFVPSGGPYDALDNAYKTCSVVGARPGELYVNGSDFIMESYRY NPSNLWRNLGILIAFCIFFHITYIACVEVVRGKRSKGEVLVFPRSYKKLSASKENSQDKDIEKKTENGIEAQRGIFQWED VCYDIKIKGEPRRILDHVDGWVKPGTLTALMGASGAGKTTLLDALADRITMGVVTGNVLVNGRQRDTSFQRKTGYAQQQD VHLPTSTVREALEFSALLRQPDTYTKEEKLAYVDEVIKILEMEKYSDAVVGVPGEGLNVEQRKRLTIGVELAARPELLLF LDEPTSGLDSQTAWSIMMLMKKLTNNGQAILCTIHQPSAVLFQQFDRLLLLQKGGKTVYYGDLGENAKKMISYFERNGAP QCPPDANPAEWMLTITNSELAEEWHQIWKNSPEYRQTKNDLKAMASQSLIEFPESDENPDLKKNYAVSSLRQIPIVTKRA FLNFWRDPLYIWSKLLLTVGLSFFIGIAFWKAENTIQGLNNQLYAIFMIIVIFISFVEQMMVPFVEQRTIYETRERPSKT YSWGTFLTSMYAAELFWGVFTAVLSFFCFYYPVGLYRNAEPTDAVSERGALFFLFYLIFYIFSVTFSYMVIAAIPNADTG GNISNTIFNVCVAMCGIFATKDEMPGFWIFMYYLSPFTYIASGFLSTGIASSEVICSANEILHFPQLPESNMTCQQYLDP YSSATGGRILNPGATSNCEYCPMNNTDIYLDRVNAPYSHAWRNFGIVVGYTVFNLAMTYLLYWIFRVPKKFNKKSPKKE
GO term prediction
Biological Process
GO:0006810 transport
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATPase activity
GO:0042626 ATPase activity, coupled to transmembrane movement of substances
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane