Protein
MCA_02550_1
Length
1,459 amino acids
Gene name: PDR5B
Description: plasma membrane ATP-binding cassette (ABC) transporter; involved in multidrug resistance
Browser: contigB:1620767-1625354+
RNA-seq: read pairs 3788, FPKM 32.1, percentile rank 54.6% (100% = highest expression)
Protein function
| Annotation: | PDR5B | plasma membrane ATP-binding cassette (ABC) transporter; involved in multidrug resistance | |
|---|---|---|---|
| EGGNOG: | 0PFN7 | PGUG_04203 | (ABC) transporter |
| SGD closest match: | S000005679 | PDR5 | Pleiotropic ABC efflux transporter of multiple drugs |
| CGD closest match: | CAL0000201396 | CDR4 | Cdr4p |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_01039_1 | 64.26% | 1441 | 0.0 | MIA_01039_1 |
| A0A0J9XKE4_GEOCN | 60.34% | 1417 | 0.0 | Similar to Saccharomyces cerevisiae YDR011W SNQ2 Plasma membrane ATP-binding cassette (ABC) transporter OS=Geotrichum candidum GN=BN980_GECA23s00131g PE=3 SV=1 |
| A0A060T914_BLAAD | 53.70% | 1471 | 0.0 | ARAD1D07634p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D07634g PE=3 SV=1 |
| UniRef50_A0A060T914 | 53.70% | 1471 | 0.0 | ARAD1D07634p n=220 Tax=Dikarya TaxID=451864 RepID=A0A060T914_BLAAD |
| A0A1E4TEV9_9ASCO | 52.85% | 1421 | 0.0 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_103973 PE=3 SV=1 |
| Q6CET9_YARLI | 53.24% | 1452 | 0.0 | YALI0B12980p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B12980g PE=3 SV=1 |
| A0A161HI40_9ASCO | 50.66% | 1441 | 0.0 | ATP-binding cassette multidrug transporter PDR5 OS=Sugiyamaella lignohabitans GN=PDR5 PE=3 SV=1 |
| A0A1D8PE84_CANAL | 49.93% | 1412 | 0.0 | Cdr4p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CDR4 PE=3 SV=1 |
| PDR5_YEAST | 47.95% | 1462 | 0.0 | Pleiotropic ABC efflux transporter of multiple drugs OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PDR5 PE=1 SV=1 |
| A0A1E3PG12_9ASCO | 40.32% | 1384 | 0.0 | Plasma membrane ATP-binding cassette transporter OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83866 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0139
Protein family membership
None predicted.
Domains and repeats
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Domain
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Domain
1
200
400
600
800
1000
1200
1459
Detailed signature matches
no IPR
Unintegrated signatures
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CYTOPLASMIC_D... (C...)
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NON_CYTOPLASM... (N...)
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TRANSMEMBRANE (Tran...)
Protein sequence
>MCA_02550_1 MSDSNDVSDIERYHGEFTYSTEKDDNKYSDVASTISFPASLNPIINPDRASALDPSNPEFSFKNWAKHILKLQKSDPEKF PLLEMGVSFKGLTAYGYEGGSNYQKTVLNILFDITKIPMLVFKNNKRKEKNKTELLHDFNGLVRSGETCVVLGRPGAGCS TFLKSIACDTYGFHIDESSVINFQGLSQKDIRNHYRGEVVYNAENEVHYPHLTVGDTLKFAALARTPEIRFGDVTRDEYA CHMRDVVMASFGLLHTMNTQVGNDYVRGVSGGERRRVSICEVTLGGALVQCFDNSTRGLDSSSALTFIQNAKVGAEISGA TVFISLYQASQDAYDLFDKVTVLYLGKQIYFGSAKNAKKFFEDMGYVCIDRQTTGDFLTSLTSPAERVIKPGFEDKVPRT PDEFEAYWKASPEFAELMKEIEEFNTTYPIRSEEQLQISQTYKNAKQSKHARKKSPYFLSYWRQIQICIFRGFQRLKIDY VMTLTSVIGNTIAALLVSSIFYNLPKDTGSFYHRSAALFFAVLFNALSSLLEVFALYAMRPIVEKHNKYAFYHPSADAIS SLIVDMPGKIVTSLAFNMVLYFMVNLRREPGPFFIFFLFAMMCVLTMSAMFRTIASVTKSVPQSLAPASFIIMMIITTMG FVIPVVNMHPWIRWINYINPIAYAFEAMMINEYRNREFRCTSIIPSGGAYDSLPYDQRSCSVVGAKPGQTYVNGSDYIIE SYEYMPSHLWRNFGIIIAFCVFFHFTYFFFVEHIKGQRSKGEVLIFPRGHEAISNSSGKSQNVEAHYNEMDKKAESSGSE EGKLSSQRGVFQWHDVCYDITIKGEPRRLLDHVDGWVKPGTLTALMGASGAGKTTLLDTLADRVTMGVVTGSMLVNGHQR DASFQRKTGYAQQQDIHMATSTVREALEFSALLRQPDTYTKEEKLAYVDEVIKILEMEKYSDAVVGVPGEGLNIEQRKRL TIGVELAARPELLLFLDEPTSGLDSQTAWSVMMLMKKLTNSGQAILCTIHQPSAVLFQQFDRLLLLKSGGQTVYYGDLGD RATKMISYFERNGAHPCPPDANPAEWMLEVIGAAPGSQSEQDWFDIWRSSPEYAQTQEELAQLAHQSAIDFPQTEKEHHL QKSYALPIFRQIPIVAKRAFLDTWRDPMYIWSKLTLTMGLSLFLGIEFLNAENTIQGLQNQLYAIFMVTVIFISMVEQLM VPFVEHRTLYETRERPSKTYSWVTFMTSMFLAEAPWLIFSGTLSFVFFYYPVGFYRNARFTDSVSEKGALFFLLYVMFYL FGLSFGYMIIAAIPDADTGGNINNVLFNICLAMSGVFATKDEMPGFWIFMYYLSPFRYIISALLSTGISGAPVECAQREL TLFPTTPEPGMTCGEFLGPYSNATQGRILNPEALTNCEYCTMSTTDTYLDRINCKFEDAWRNFGIIILYTVFNVGMSYFF YWLGRVPKPWSKKKVEKLE
GO term prediction
Biological Process
GO:0006810 transport
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATPase activity
GO:0042626 ATPase activity, coupled to transmembrane movement of substances
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane