Protein

MCA_02549_1

Length
430 amino acids

Gene name: NPT1

Description: Nicotinate phosphoribosyltransferase

Browser: contigB:1617938-1619357-

RNA-seq: read pairs 1114, FPKM 31.9, percentile rank 54.5% (100% = highest expression)

Protein function

Annotation:NPT1Nicotinate phosphoribosyltransferase
KEGG:K00763pncB nicotinate phosphoribosyltransferase [EC:6.3.4.21]
EGGNOG:0PG8TNPT1Nicotinate phosphoribosyltransferase
SGD closest match:S000005735NPT1Nicotinate phosphoribosyltransferase
CGD closest match:CAL0000174810NPT1Nicotinate phosphoribosyltransferase

Protein alignments

%idAln lengthE-value
MIA_02918_164.69%4390.0MIA_02918_1
A0A0J9X9T3_GEOCN62.62%4280.0Nicotinate phosphoribosyltransferase OS=Geotrichum candidum GN=BN980_GECA06s02419g PE=3 SV=1
A0A1E3PPP3_9ASCO61.54%4290.0Nicotinate phosphoribosyltransferase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_49834 PE=3 SV=1
A0A060T1N1_BLAAD60.52%4230.0Nicotinate phosphoribosyltransferase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C17842g PE=3 SV=1
Q6CG74_YARLI59.95%4172e-176Nicotinate phosphoribosyltransferase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B00220g PE=3 SV=1
UniRef50_G8YDD759.43%4199e-173Nicotinate phosphoribosyltransferase n=5 Tax=Saccharomycetales TaxID=4892 RepID=G8YDD7_PICSO
NPT1_YEAST56.88%4295e-176Nicotinate phosphoribosyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NPT1 PE=1 SV=3
A0A1D8PRI0_CANAL58.16%4235e-172Nicotinate phosphoribosyltransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=NPT1 PE=3 SV=1
A0A1E4TFR2_9ASCO55.12%4302e-168Nicotinate phosphoribosyltransferase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_108275 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2137

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 430

Detailed signature matches

  1. Family IPR007229
    Nicotinate phosphoribosyltransferase family
    1. PF04095 (NAPRTase)
    2. PIRSF000484 (NAPRT)
  2. Family IPR006406
    Nicotinate phosphoribosyltransferase
    1. TIGR01514
    2. MF_00570 (NAPRTase)
  3. Domain IPR002638
    Quinolinate phosphoribosyl transferase, C-terminal
    1. SSF51690 (Nicotinat...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.20.14...
  2. SSF54675 (Nicotinat...)

Protein sequence

>MCA_02549_1
MTLENPVITSLLDTDLYKLTMQAGVFADFSDAQVEYTYTNRTPDKKYTSEAFEWLKNQINSLGNLKFTSDEIEFLKKEAP
YLPSSYFEYLKTFKLDPSSQVSLKFIEETSNLDITIKGLWVETILYEIPILALVSEGYFKFVETDWDYEGQLDLAKHKGS
SLLKHECKFSEFGTRRRRSFKSQEIVIQGLIESAKLPNSDKLNPLFLGTSNVFFAKKYNLKPIGTVAHEWMMGIASYTQD
YVNANKMSMDKWIDTMGKDAAGFALTDTFGTEDFLKHFKPPYTDAYKGVRQDSGDPLEYTKKIGEHYRALGYPDKSKGII
YSDSLDIEKCILYKKAAEDNGLVPFFGVGTFFTNDFKEKSNPSKKSVPLNIVIKISKVNGYPAIKISDNINKNTGDKDTV
LKVKKELGYIEKDWSQGDESHRWDESKDID

GO term prediction

Biological Process

GO:0009435 NAD biosynthetic process
GO:0019357 nicotinate nucleotide biosynthetic process

Molecular Function

GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity
GO:0004516 nicotinate phosphoribosyltransferase activity

Cellular Component

None predicted.