Protein

MCA_02541_1

Length
371 amino acids

Browser: contigB:1597261-1598377+

RNA-seq: read pairs 1018, FPKM 33.8, percentile rank 56.0% (100% = highest expression)

Protein function

KEGG:K00002AKR1A1 alcohol dehydrogenase (NADP+) [EC:1.1.1.2]
EGGNOG:0PG90alcohol dehydrogenase
SGD closest match:S000004937ADH6NADP-dependent alcohol dehydrogenase 6
CGD closest match:CAL0000187810orf19.5517NADP-dependent alcohol dehydrogenase

Protein alignments

%idAln lengthE-value
MIA_03123_160.77%3624e-158MIA_03123_1
A0A1E4TMD6_9ASCO57.73%3624e-147Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_95529 PE=3 SV=1
UniRef50_W1Q6P653.09%3561e-115NADP-dependent alcohol dehydrogenase 7 n=19 Tax=Saccharomycetales TaxID=4892 RepID=W1Q6P6_OGAPD
A0A1E3PTC8_9ASCO43.53%3635e-95GroES-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_49175 PE=3 SV=1
ADH6_YEAST44.75%3629e-90NADP-dependent alcohol dehydrogenase 6 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ADH6 PE=1 SV=1
A0A167CUK7_9ASCO39.56%3645e-75Adh6p OS=Sugiyamaella lignohabitans GN=ADH6 PE=3 SV=1
Q5AC33_CANAL37.64%3641e-69NADP-dependent alcohol dehydrogenase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.5517 PE=3 SV=1
Q6C6P0_YARLI28.19%2983e-20YALI0E07766p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E07766g PE=3 SV=2
A0A060TEC7_BLAAD26.63%3535e-20ARAD1D06028p OS=Blastobotrys adeninivorans GN=AADH2 PE=3 SV=1
A0A0J9X8H3_GEOCN27.30%3594e-18Similar to Saccharomyces cerevisiae YMR083W ADH3 Mitochondrial alcohol dehydrogenase isozyme III OS=Geotrichum candidum GN=BN980_GECA05s06181g PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0175

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 50 100 150 200 250 300 371

Detailed signature matches

  1. Domain IPR011032
    GroES-like
    1. SSF50129 (GroES-like)
  2. Domain IPR020843
    Polyketide synthase, enoylreductase domain
    1. SM00829 (PKS_ER_nam...)
  3. Domain IPR013154
    Alcohol dehydrogenase, N-terminal
    1. PF08240 (ADH_N)
  4. Domain IPR016040
    NAD(P)-binding domain
    1. SSF51735 (NAD(P)-bi...)
  5. Domain IPR013149
    Alcohol dehydrogenase, C-terminal
    1. PF00107 (ADH_zinc_N)
  6. SITE IPR002328
    Alcohol dehydrogenase, zinc-type, conserved site
    1. PS00059 (ADH_ZINC)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50.20
  2. G3DSA:3.90.18...
  3. cd05283 (CAD1)

Residue annotation

  1. catalytic Zn bindi...
  2. putative substrate...
  3. putative NAD(P) bi...
  4. structural Zn bind...
  5. dimer interface cd...

Protein sequence

>MCA_02541_1
MVYPETFQALGLTEWEDYPHPKRFEYKPQEFRPYDVDIEIECCGVCGSDIHAAAGNWGHPYLPLAVGHEIIGRAIKVGPE
ATSKYGIKVGDRVGVGAQCDCDDTCYSCQVKLENLCQNNKGTYFGQYENGYNTVGGNASHVRTNGKFVFKIPDAISSEHA
APLLCGGVTGFSPLLQAGVTKGTKVGVVGLGGIGSMTVQFAVALGAEVTVISRSHAKEEDARKMGASHFIASSIPEEIKA
NGDTLDLIVNTTSSFSDSALTSFLTILRPRGKLIFITFPPNGEMVVLPPAQLLFRGISVQGSALGTPEEIKYMLNFAAEH
GIKPWVETVDINEKNLGECWEKTQAAKAHYRFVMTGYNKFFDQGSSNSPKM

GO term prediction

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0008270 zinc ion binding
GO:0016491 oxidoreductase activity

Cellular Component

None predicted.