Protein

MCA_02535_1

Length
482 amino acids

Browser: contigB:1581199-1582648+

RNA-seq: read pairs 2454, FPKM 62.8, percentile rank 70.2% (100% = highest expression)

Protein function

KEGG:K00814GPT alanine transaminase [EC:2.6.1.2]
EGGNOG:0PGK7PGUG_02164alanine aminotransferase
SGD closest match:S000004079ALT1Probable alanine aminotransferase, mitochondrial
CGD closest match:CAL0000189002ALT1Alanine transaminase

Protein alignments

%idAln lengthE-value
MIA_02884_177.07%4840.0MIA_02884_1
A0A0J9XER6_GEOCN70.71%4780.0Similar to Saccharomyces cerevisiae YLR089C ALT1 Alanine transaminase (Glutamic pyruvic transaminase) OS=Geotrichum candidum GN=BN980_GECA13s01825g PE=4 SV=1
A0A161HG92_9ASCO65.28%4810.0Alanine transaminase ALT1 OS=Sugiyamaella lignohabitans GN=ALT1 PE=4 SV=1
UniRef50_A0A161HG9265.28%4810.0Alanine transaminase ALT1 n=177 Tax=Opisthokonta TaxID=33154 RepID=A0A161HG92_9ASCO
A0A1E3PEB3_9ASCO66.81%4760.0Putative alanine aminotransferase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_53376 PE=4 SV=1
A0A060SWX3_BLAAD66.39%4760.0ARAD1A03696p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A03696g PE=4 SV=1
Q6CA32_YARLI59.58%4750.0YALI0D06325p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D06325g PE=4 SV=1
ALAM_YEAST57.68%4820.0Probable alanine aminotransferase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ALT1 PE=1 SV=1
A0A1E4TJA7_9ASCO54.38%4910.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_23530 PE=4 SV=1
A0A1D8PJP4_CANAL52.88%4860.0Alanine transaminase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ALT1 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1608

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 400 450 482

Detailed signature matches

  1. Domain IPR015424
    Pyridoxal phosphate-dependent transferase
    1. SSF53383 (PLP-depen...)
  2. Domain IPR004839
    Aminotransferase, class I/classII
    1. PF00155 (Aminotran_1_2)
  3. Domain IPR015421
    Pyridoxal phosphate-dependent transferase, major region, subdomain 1
    1. G3DSA:3.40.64...
  4. Domain IPR015422
    Pyridoxal phosphate-dependent transferase, subdomain 2
    1. G3DSA:3.90.11...
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd00609 (AAT_like)

Residue annotation

  1. pyridoxal 5'-phosp...
  2. homodimer interfac...
  3. catalytic residue ...

Protein sequence

>MCA_02535_1
MPKLPSPLTIDKLNANVVNAKYAVRGRLAIRAEQLKNLIKENPEKYPFKQVINANIGNPQQLDQKPITFYRQVLSLIEYP
QLLDKKETSLLFKADAIARARKLVENIGSVGAYSNAQGVEIVRKSVAKFISERDGYPASPEHIYLTTGASSAVTMLLNAQ
ATGKDAGFLIPIPQYPLYSASLTLMGATAVQYHLDESKGWATNVEEIRDIVAEARDEGIDLKTIVVINPGNPTGSILTEE
NISGIIDIAAENGLVIIADEVYQANVYIGEFISFKKVLRKLQETDPKKYEHVQLASLHSTSKGMIGECGHRGGYMELVGF
KPEVEEVIYKLGAIQLCPVVMGQCVVELMVNPPKKGDESYEEFTKEYNGIYETLKHRANVLYNAFQEMEGVSCQKPEGAM
YLFPKITLPKKALEEAKRLNEVPDELYCLELLEQTGICVIPGSGFGQQEGTFHFRTTFLAPVEDYADLLTSFHKRFMDKY
RD

GO term prediction

Biological Process

GO:0009058 biosynthetic process

Molecular Function

GO:0003824 catalytic activity
GO:0030170 pyridoxal phosphate binding

Cellular Component

None predicted.