Protein
MCA_02533_1
Length
216 amino acids
Gene name: ADE8
Description: Phosphoribosylglycinamide formyltransferase
Browser: contigB:1578388-1579039+
RNA-seq: read pairs 1318, FPKM 75.0, percentile rank 74.0% (100% = highest expression)
Protein function
Annotation: | ADE8 | Phosphoribosylglycinamide formyltransferase | |
---|---|---|---|
KEGG: | K00601 | E2.1.2.2 | phosphoribosylglycinamide formyltransferase [EC:2.1.2.2] |
EGGNOG: | 0PNSU | FG08429.1 | phosphoribosylglycinamide formyltransferase |
SGD closest match: | S000002816 | ADE8 | Phosphoribosylglycinamide formyltransferase |
CGD closest match: | CAL0000195096 | ADE8 | Phosphoribosylglycinamide formyltransferase |
Protein alignments
%id | Aln length | E-value | ||
---|---|---|---|---|
MIA_02886_1 | 75.24% | 210 | 4e-115 | MIA_02886_1 |
A0A0J9XG00_GEOCN | 73.83% | 214 | 7e-113 | Similar to Saccharomyces cerevisiae YDR408C ADE8 Phosphoribosyl-glycinamide transformylase OS=Geotrichum candidum GN=BN980_GECA14s01418g PE=3 SV=1 |
A0A060T210_BLAAD | 71.90% | 210 | 7e-108 | ARAD1A03652p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A03652g PE=4 SV=1 |
A0A167D360_9ASCO | 71.36% | 213 | 7e-106 | Phosphoribosylglycinamide formyltransferase OS=Sugiyamaella lignohabitans GN=ADE8 PE=4 SV=1 |
A0A1E3PJC0_9ASCO | 69.01% | 213 | 4e-103 | Phosphoribosyl-glycinamide transformylase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_50812 PE=4 SV=1 |
Q6CAG1_YARLI | 68.22% | 214 | 1e-97 | YALI0D03069p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D03069g PE=3 SV=1 |
A0A1D8PGS7_CANAL | 61.16% | 224 | 2e-90 | Phosphoribosylglycinamide formyltransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ADE8 PE=4 SV=1 |
UniRef50_A0A1D8PGS7 | 61.16% | 224 | 6e-87 | Phosphoribosylglycinamide formyltransferase n=24 Tax=Saccharomycetales TaxID=4892 RepID=A0A1D8PGS7_CANAL |
A0A1E4TGX7_9ASCO | 59.81% | 214 | 8e-81 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_2726 PE=3 SV=1 |
PUR3_YEAST | 56.48% | 216 | 5e-70 | Phosphoribosylglycinamide formyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ADE8 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.1687
Protein family membership
- Phosphoribosylglycinamide formyltransferase (IPR004607)
Domains and repeats
-
Domain
1
20
40
60
80
100
120
140
160
180
200
216
Detailed signature matches
no IPR
Unintegrated signatures
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NON_CYTOPLASM... (N...)
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SIGNAL_PEPTIDE (Sig...)
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SIGNAL_PEPTID... (S...)
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SIGNAL_PEPTID... (S...)
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SIGNAL_PEPTID... (S...)
Residue annotation
-
active site cd08645
-
substrate binding ...
-
cosubstrate bindin...
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catalytic site cd0...
Protein sequence
>MCA_02533_1 MTKKVLVLISGSGTNLQALIDAAAQNKLGDGQISLVISSSPDAYGLERAKKANIPTYVHSLQSDKYYGKIPKTDKEARKE ARKAFNKDLADYILLPENKPDLIVCAGWMLILSPTFLKPLEEAKIPIINLHPALPGAFAGTHAIERAWEAGQKGEITKGG VMIHKVIAQVDEGEPLVVKEIELNKDETVEQYEDRVHKIEHVAIVEGTVKALNELA
GO term prediction
Biological Process
GO:0006189 'de novo' IMP biosynthetic process
GO:0009058 biosynthetic process
Molecular Function
GO:0004644 phosphoribosylglycinamide formyltransferase activity
GO:0016742 hydroxymethyl-, formyl- and related transferase activity
Cellular Component
None predicted.